HumanLectome - A database of all human lectins

HumanLectome - A database of all the human lectins HumanLectome
A database of all the human lectins

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UniLectin class

Known lectin group

Lectin confidence

Name (prot, mRNA, gene), ID, ...

UniProt AC

NCBI AC

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LectomeXplore UniLectin3D

1 identified lectin class(es)

I-type lectin

Lectin Status Distribution

Curated

Low evidence

Very low evidence

NCBI: NP_003821

UniLectin3D LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-5

Synonym(s)

Sialic acid-binding Ig-like lectin 5 (Siglec-5) (CD33 antigen-like 2) (Obesity-binding protein 2) (OB-BP2) (OB-binding protein 2) (CD antigen CD170)

HGNC gene name

SIGLEC5

HGNC name

sialic acid binding Ig like lectin 5

Protein_CD_name

CD170

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - CD33-related Siglecs

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-6)GalNAc

NCBI: NP_055257

UniLectin3D LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-8

Synonym(s)

Sialic acid-binding Ig-like lectin 8 (Siglec-8) (Sialoadhesin family member 2) (SAF-2)

HGNC gene name

SIGLEC8

HGNC name

sialic acid binding Ig like lectin 8

Protein_CD_name

CD329

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - CD33-related Siglecs

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-6)(6S)Gal(b1-4)GlcNAc

NCBI: NP_055200

UniLectin3D LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-7

Synonym(s)

Sialic acid-binding Ig-like lectin 7 (Siglec-7) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (CDw328) (D-siglec) (QA79 membrane protein) (p75) (CD antigen CD328)

HGNC gene name

SIGLEC7

HGNC name

sialic acid binding Ig like lectin 7

Protein_CD_name

CD328

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - CD33-related Siglecs

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-8)Neu5Ac(a2-3)Gal

NCBI: NP_001762

UniLectin3D LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-2

Synonym(s)

B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22)

HGNC gene name

CD22

HGNC name

CD22 molecule

Protein_CD_name

CD22

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - Siglecs common to mammals

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-6)Gal(b1-4)(6S)GlcNAc

NCBI: NP_001763

UniLectin3D LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-3

Synonym(s)

Myeloid cell surface antigen CD33 (Sialic acid-binding Ig-like lectin 3) (Siglec-3) (gp67) (CD antigen CD33)

HGNC gene name

CD33

HGNC name

CD33 molecule

Protein_CD_name

CD33

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - CD33-related Siglecs

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-6)Gal(b1-4)GlcNAc

NCBI: NP_038467

UniLectin3D LectomeXplore HumanLectome Entry HL Entry

Protein name

Paired immunoglobulin-like type 2 receptor alpha

Synonym(s)

Paired immunoglobulin-like type 2 receptor alpha (Cell surface receptor FDF03) (Inhibitory receptor PILR-alpha)

HGNC gene name

PILRA

HGNC name

paired immunoglobin like type 2 receptor alpha

Protein_CD_name

Undefined

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

Undefined

Lectin fold

b-sandwich / Ig-like

Glycan specificity

Sialylated O-glycans

NCBI: NP_998767

UniLectin3D LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-15

Synonym(s)

Sialic acid-binding Ig-like lectin 15 (Siglec-15) (CD33 antigen-like 3)

HGNC gene name

SIGLEC15

HGNC name

sialic acid binding Ig like lectin 15

Protein_CD_name

Undefined

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - Siglecs common to mammals

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-6)GalNAc

NCBI: NP_004224

UniLectin3D HumanLectome Entry HL Entry

Protein name

CD83

Synonym(s)

CD83 antigen (hCD83) (B-cell activation protein) (Cell surface protein HB15) (CD antigen CD83)

HGNC gene name

CD83

HGNC name

CD83 molecule

Protein_CD_name

CD83

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc

NCBI: NP_002352

LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-4

Synonym(s)

Myelin-associated glycoprotein (Siglec-4a)

HGNC gene name

MAG

HGNC name

myelin associated glycoprotein

Protein_CD_name

Undefined

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - Siglecs common to mammals

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-3)Gal(b1-3)GalNAc

NCBI: NP_001092082

LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-14

Synonym(s)

Sialic acid-binding Ig-like lectin 14 (Siglec-14)

HGNC gene name

SIGLEC14

HGNC name

sialic acid binding Ig like lectin 14

Protein_CD_name

Undefined

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - CD33-related Siglecs

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-6)GalNAc

NCBI: NP_055256

LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-9

Synonym(s)

Sialic acid-binding Ig-like lectin 9 (Siglec-9) (CDw329) (Protein FOAP-9) (CD antigen CD329)

HGNC gene name

SIGLEC9

HGNC name

sialic acid binding Ig like lectin 9

Protein_CD_name

Undefined

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - CD33-related Siglecs

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-6)Gal(b1-4)[Fuc(a1-3)](6S)GlcNAc

NCBI: NP_149121

LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-10

Synonym(s)

Sialic acid-binding Ig-like lectin 10 (Siglec-10) (Siglec-like protein 2)

HGNC gene name

SIGLEC10

HGNC name

sialic acid binding Ig like lectin 10

Protein_CD_name

Undefined

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - CD33-related Siglecs

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-6)Gal(b1-4)GlcNAc

NCBI: NP_443116

LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-11

Synonym(s)

Sialic acid-binding Ig-like lectin 11 (Sialic acid-binding lectin 11) (Siglec-11)

HGNC gene name

SIGLEC11

HGNC name

sialic acid binding Ig like lectin 11

Protein_CD_name

Undefined

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - CD33-related Siglecs

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-8)Neu5Ac(a2-3)Gal

NCBI: NP_001335293

LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-16

Synonym(s)

Sialic acid-binding Ig-like lectin 16 (Siglec-16) (Siglec-P16)

HGNC gene name

SIGLEC16

HGNC name

sialic acid binding Ig like lectin 16

Protein_CD_name

Undefined

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - CD33-related Siglecs

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-8)Neu5Ac(a2-3)Gal

NCBI: NP_001236

LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-6

Synonym(s)

Sialic acid-binding Ig-like lectin 6 (Siglec-6) (CD33 antigen-like 1) (CDw327) (Obesity-binding protein 1) (OB-BP1) (CD antigen CD327)

HGNC gene name

SIGLEC6

HGNC name

sialic acid binding Ig like lectin 6

Protein_CD_name

CD327

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - CD33-related Siglecs

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-6)GalNAc

NCBI: NP_075556

LectomeXplore HumanLectome Entry HL Entry

Protein name

SIGLEC-1

Synonym(s)

Sialoadhesin (Sialic acid-binding Ig-like lectin 1) (Siglec-1) (CD antigen CD169)

HGNC gene name

SIGLEC1

HGNC name

sialic acid binding Ig like lectin 1

Protein_CD_name

CD169

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins - Siglecs common to mammals

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc / Neu5Ac(a2-3)Gal(b1-4)GlcNAc

NCBI: NP_000416

LectomeXplore HumanLectome Entry HL Entry

Protein name

L1 cell adhesion molecule

Synonym(s)

Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171)

HGNC gene name

L1CAM

HGNC name

L1 cell adhesion molecule

Protein_CD_name

CD171

Lectin confidence

Curated

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins

Lectin fold

b-sandwich / Ig-like

Glycan specificity

NeuAc

NCBI: NP_851996

UniLectin3D LectomeXplore HumanLectome Entry HL Entry

Protein name

Neural cell adhesion molecule 1

Synonym(s)

Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56)

HGNC gene name

NCAM1

HGNC name

neural cell adhesion molecule 1

Protein_CD_name

CD56

Lectin confidence

Low evidence

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins

Lectin fold

b-sandwich / Ig-like

Glycan specificity

Oligomannose

NCBI: NP_000192

UniLectin3D HumanLectome Entry HL Entry

Protein name

Intercellular adhesion molecule 1

Synonym(s)

Intercellular adhesion molecule 1 (ICAM-1) (Major group rhinovirus receptor) (CD antigen CD54)

HGNC gene name

ICAM1

HGNC name

intercellular adhesion molecule 1

Protein_CD_name

CD54

Lectin confidence

Low evidence

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins

Lectin fold

b-sandwich / Ig-like

Glycan specificity

Hyaluronan

NCBI: NP_001315538

UniLectin3D HumanLectome Entry HL Entry

Protein name

CD2

Synonym(s)

T-cell surface antigen CD2 (Erythrocyte receptor) (LFA-2) (LFA-3 receptor) (Rosette receptor) (T-cell surface antigen T11/Leu-5) (CD antigen CD2)

HGNC gene name

CD2

HGNC name

CD2 molecule

Protein_CD_name

CD2

Lectin confidence

Low evidence

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins

Lectin fold

b-sandwich / Ig-like

Glycan specificity

Sulfated

NCBI: NP_004531

LectomeXplore HumanLectome Entry HL Entry

Protein name

Neural cell adhesion molecule 2

Synonym(s)

Neural cell adhesion molecule 2 (N-CAM-2) (NCAM-2)

HGNC gene name

NCAM2

HGNC name

neural cell adhesion molecule 2

Protein_CD_name

Undefined

Lectin confidence

Very low evidence

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins

Lectin fold

b-sandwich / Ig-like

Glycan specificity

Unknown

NCBI: NP_000521

HumanLectome Entry HL Entry

Protein name

Myelin protein zero

Synonym(s)

Myelin protein P0 (Myelin peripheral protein) (MPP) (Myelin protein zero)

HGNC gene name

MPZ

HGNC name

myelin protein zero

Protein_CD_name

Undefined

Lectin confidence

Very low evidence

UniLectin class

I-type lectin

Known lectin group

I-Type Lectins

Lectin fold

b-sandwich / Ig-like

Glycan specificity

Uncharacterised

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