NCBI Summary
The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein and may function in selective fasciculation and zone-to-zone projection of the primary olfactory axons. [provided by RefSeq, Jul 2008].
Protein
Protein (NP_004531)
Neural cell adhesion molecule 2
Neural cell adhesion molecule 2 (N-CAM-2) (NCAM-2)
NCAM2
neural cell adhesion molecule 2
Undefined
Very low evidence
I-type lectin
I-Type Lectins
b-sandwich / Ig-like
MSLLLSFYLLGLLVSSGQALLQVTISLSKVELSVGESKFFTCTAIGEPESIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIGTRFQEYILALADVPSSPYGVKIIELSQTTAKVSFNKPDSHGGVPIHHYQVDVKEVASEIWKIVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGKGQGDYSKIEIFQTLPVREPSPPSIHGQPSSGKSFKLSITKQDDGGAPILEYIVKYRSKDKEDQWLEKKVQGNKDHIILEHLQWTMGYEVQITAANRLGYSEPTVYEFSMPPKPNIIKDTLFNGLGLGAVIGLGVAALLLILVVTDVSCFFIRQCGLLMCITRRMCGKKSGSSGKSKELEEGKAAYLKDGSKEPIVEMRTEDERVTNHEDGSPVNEPNETTPLTEPEKLPLKEEDGKEALNPETIEIKVSNDIIQSKEDDSKA
Mol* PDB structure viewer
Structural models
SWISS-MODEL structural models
The location of the lectin domain structural model is: 167-302
We infer [1.63, 2.13] Å as the interval of error of this structural model.
Template 1: 5LFR chain: A, P20917, NP_001333015.1, sequence identity: 22.8%, coverage: 94.1%, location in sequence: 19-331, (19-331 in PDB).
Template 2: 2N7B chain: A, Q9NYZ4, NP_055257.2, sequence identity: 18.4%, coverage: 72.8%, location in sequence: 26-152, (10-136 in PDB).
Template 3: 2ZG1 chain: A, O15389, NP_003821.1, sequence identity: 17.6%, coverage: 71.3%, location in sequence: 20-141, (25-146 in PDB).
Show the alignment used for the construction of the structural model, Download.
Show the plot of DOPE energy score, Download.
We infer [1.63, 2.13] Å as the interval of error of this structural model.
Template 1: 5LFR chain: A, P20917, NP_001333015.1, sequence identity: 22.8%, coverage: 94.1%, location in sequence: 19-331, (19-331 in PDB).
Template 2: 2N7B chain: A, Q9NYZ4, NP_055257.2, sequence identity: 18.4%, coverage: 72.8%, location in sequence: 26-152, (10-136 in PDB).
Template 3: 2ZG1 chain: A, O15389, NP_003821.1, sequence identity: 17.6%, coverage: 71.3%, location in sequence: 20-141, (25-146 in PDB).
Show the alignment used for the construction of the structural model, Download.
Show the plot of DOPE energy score, Download.
Ligand
Glycan ligands from structural data
No crystal structures of complexes with glycan ligand.
References
NCBI References (10 PubMed Identifiers)
- Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo. [33548223]
- NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor. [29895898]
- NCAM2 deletion in a boy with macrocephaly and autism: Cause, association or predisposition? [27596683]
- Abeta-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease. [26611261]
- NCAM2/OCAM/RNCAM: cell adhesion molecule with a role in neuronal compartmentalization. [22155300]
- Crystal structure of the Ig1 domain of the neural cell adhesion molecule NCAM2 displays domain swapping. [18706912]
- Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues. [15146195]
- Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. [12754519]
- Differential function of RNCAM isoforms in precise target selection of olfactory sensory neurons. [12538518]
- Cloning of a novel human neural cell adhesion molecule gene (NCAM2) that maps to chromosome region 21q21 and is potentially involved in Down syndrome. [9226371]
UniProt Main References (3 PubMed Identifiers)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. [14702039]
- The DNA sequence of human chromosome 21. [10830953]
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). [15489334]
All isoforms of this gene containing a lectin domain
RNA
RNA (Transcript ID: NM_004540.5)
neural cell adhesion molecule 2, transcript variant 2
m7G-5')ppp(5'-ACUUUGCGAGGAGGAGCGCGCGGGCUGCGGGCGGCUGGGGCACCGCGGGAGCGGCGGCGGCGGCUCUAGCAGAGGCGGCCGGGGCAGCGAAAGGUUCUCUCUCCAGGGCUGGACUUAAUAACUUUGAAACUGUCCACCGGUGUCACGUCCUGAACAUGAGCCUCCUCCUCUCCUUCUACCUGCUGGGGUUGCUUGUCAGUAGCGGGCAAGCUCUUCUUCAAGUGACAAUUUCACUUAGCAAAGUAGAGCUUAGUGUUGGAGAAUCUAAAUUCUUCACAUGUACAGCGAUUGGUGAACCUGAAAGUAUAGAUUGGUAUAAUCCUCAAGGAGAGAAGAUAAUUUCAACACAGAGGGUAGUAGUGCAAAAGGAAGGUGUUAGGUCACGGUUAACCAUCUACAAUGCAAAUAUAGAAGAUGCAGGGAUAUAUCGUUGUCAAGCAACAGAUGCCAAAGGACAAACACAAGAAGCUACAGUAGUUUUGGAAAUUUACCAAAAACUCACUUUCAGAGAAGUGGUAUCUCCACAAGAAUUCAAACAAGGAGAAGAUGCAGAAGUGGUUUGCCGAGUUAGCAGUUCACCUGCACCUGCUGUCAGCUGGUUGUAUCAUAAUGAGGAAGUCACCACUAUUUCCGACAAUCGGUUCGCUAUGUUAGCAAACAAUAACCUGCAGAUUCUCAACAUCAAUAAAAGUGAUGAAGGUAUAUACAGAUGUGAAGGAAGAGUGGAGGCCAGGGGAGAAAUUGACUUCCGUGAUAUCAUUGUUAUUGUUAAUGUGCCGCCAGCAAUCUCAAUGCCUCAGAAAUCUUUUAAUGCCACAGCAGAGAGAGGAGAAGAAAUGACAUUUUCCUGCAGGGCCUCAGGCUCUCCAGAACCCGCCAUCUCCUGGUUCAGGAAUGGCAAGCUCAUUGAAGAAAAUGAGAAGUACAUAUUGAAAGGGAGCAAUACAGAACUCACUGUCAGGAACAUAAUCAAUAGUGAUGGUGGUCCUUAUGUCUGCAGGGCCACAAAUAAGGCAGGAGAAGAUGAAAAGCAAGCUUUCCUCCAAGUCUUUGUACAGCCUCACAUAAUACAGCUUAAAAAUGAAACUACAUAUGAGAAUGGUCAAGUCACACUCGUAUGUGAUGCGGAAGGGGAGCCUAUUCCAGAAAUCACUUGGAAAAGAGCUGUGGAUGGCUUCACGUUCACUGAAGGCGAUAAGAGCCUGGACGGCCGUAUCGAAGUCAAAGGGCAGCAUGGAAGCUCAUCACUGCAUAUUAAAGAUGUGAAGUUGUCAGAUUCAGGGAGAUAUGACUGUGAAGCUGCAAGCAGAAUUGGAGGGCAUCAAAAGAGCAUGUACCUUGAUAUUGAAUAUGCCCCCAAGUUUAUAUCAAACCAAACAAUUUAUUACUCUUGGGAAGGAAAUCCUAUCAAUAUAAGUUGUGAUGUGAAAUCGAAUCCACCAGCAUCAAUUCACUGGAGAAGAGAUAAAUUAGUCUUACCUGCUAAAAACACGACCAAUUUAAAGACUUAUAGUACAGGAAGAAAGAUGAUAUUAGAGAUUGCACCUACAUCUGACAAUGACUUUGGACGCUAUAAUUGCACAGCCACUAAUCAUAUAGGAACAAGAUUUCAAGAAUAUAUUCUUGCUUUGGCUGACGUGCCAUCCAGUCCCUAUGGAGUGAAGAUCAUAGAGCUGUCGCAGACCACGGCCAAGGUUUCCUUCAACAAACCGGACUCCCAUGGAGGUGUACCUAUUCAUCACUAUCAGGUGGAUGUCAAAGAAGUAGCGUCAGAAAUCUGGAAAAUUGUACGCUCCCAUGGAGUUCAAACAAUGGUUGUUUUGAACAACCUGGAACCAAAUACAACUUAUGAAAUCAGGGUUGCAGCUGUAAAUGGAAAGGGACAAGGAGACUACAGUAAAAUAGAAAUCUUCCAAACAUUACCAGUUCGUGAACCAAGUCCUCCAUCCAUACAUGGACAGCCAAGCAGUGGAAAGAGCUUUAAACUCAGCAUCACCAAACAGGACGAUGGAGGGGCCCCUAUUUUGGAAUACAUUGUGAAAUAUAGAAGUAAAGAUAAGGAAGACCAAUGGCUAGAGAAAAAAGUGCAAGGAAAUAAAGACCACAUCAUUUUGGAGCAUCUCCAGUGGACCAUGGGGUAUGAAGUUCAGAUUACAGCUGCCAAUAGAUUGGGAUAUUCUGAACCGACAGUUUAUGAAUUCAGCAUGCCACCAAAGCCCAACAUUAUUAAAGACACGCUGUUUAAUGGUCUUGGGCUUGGAGCAGUAAUUGGCCUGGGAGUUGCUGCACUGCUGCUAAUUCUUGUGGUAACAGACGUCAGCUGCUUCUUUAUUCGGCAAUGUGGGUUGCUGAUGUGCAUCACUAGGAGAAUGUGUGGAAAGAAAAGUGGCUCCAGUGGCAAAAGUAAAGAACUCGAAGAAGGAAAAGCUGCAUACCUGAAAGAUGGAUCAAAAGAACCAAUAGUGGAGAUGAGAACAGAGGAUGAAAGAGUUACUAAUCACGAAGAUGGGAGCCCAGUAAAUGAGCCAAAUGAAACCACACCACUGACAGAACCUGAAAAAUUGCCUUUAAAGGAAGAAGAUGGGAAAGAAGCUCUAAAUCCAGAAACUAUAGAAAUUAAAGUUUCUAACGACAUCAUUCAAUCAAAAGAAGACGACAGCAAAGCAUAACAACAAUAUUACAGGGGCUUGAACAACACUACGAAGAGUAUUUGGAUUGCGUGACCCUAUGACCAAAACUAUUCCAUUGACCUUAAUUUCUUGGGAAACUUCUAGCUUGGAAUAGCUUGUACACAUAUACAUAUGAUCAAAUACUCCUGCCCAUGAUCCAUUCCCUUUUGUUAUUGUUGUUGUUGUUGCUGUUGUUGUUAAUUUUGUUAAGAAUUUCAAUAUCAAGACUGACUGGCACCAACACUUUGGUAUUCAAUUUGAUUCUAUGACUGAAGUACUGGAAUUUAUUAUGUGGCUAAAGUGCUCUAUUUAUUAAGAACUAUAUUUAAUACCACCAACAAAUAUAGGGGUUAAGGAAAAAAAACGUGAGCUACAUGUGUAAGAAGGCCCUGCAUGUGUAUGAGUCCUAUUCUGGGCAAAUAGAUUCUUAAAGUGGCUUUCAACUUCAAGAUGAAGGAGCUUAAUAAUGGUUACUCAUUUUAUCAGGGGAAUUUCAGGGAACGUAGGCGUCAAAGAGCCAGUUAUCUUUAGCAGAUAUUAAAAAUUGAAAACUUUGGAGAACUCAUUUCAAGUUAUGAUUCAGUGCAUUUUCAACAUUGAUUUUUGAUAGACUGAAGUGCCAGAUCAAAAUUGUUACCCAUUUGAAAGAAUAUUAGUUGUAUAUAAAAUUAGAUUAGAAAGACUUUCUAAAUCUCUAUCUCUUUAUAUAUGUCCUAUUCAUUCACAAUGGAUUAUACAAAAAAAAGUGUAUUGCAAGUGAAAUAAUAUUGAUUUCUGCCCUCAGCUUCAAAUAAAGUAAAUUGAAAUGGGAACAAUAUCAAUAUGGUGUCUUGAUAUAUUUAUAAAUAUGUGAUUAUCAUUUAUUUUUAAAAUAAUUUAUCAAAAAACAAGUCUUUAGUGUUCAAAUACUUCAAAUCAUAUCCUCAGAUAUAUUUUUAGCCCAUGGUUUUAUAUAAUCUUUAAGAACUAAUUUUACCACUGUUAUAGGUUCACCAUUAAAUAUAAUUGGCUAAUAAAAAUUUUAAGGUUGACUAAAUUAAGAAGAAAUUAUUUAACAUUUUAAUGUGCCAUAAAAGAGUAAAUGAUAAAUAAUUAAAUGCCACUAUGUGUUCUAUUCCGGAUGUUCUAGCUAGAAGUCAUUUUAAGAUUUUGAUAAACAACUUUGGUUGAAGAAAUUCCUUAAGUAUUCAACACAAACUUUCUAAUAUCUUUUGUUAGGGUUAUACCAGAAUAAAAUGCUUCUUUACUUCCAAGCUAUGCAAGCUCCCAGAGGUAAUAGAGUGACACAUGAUUUAACUUAUAUGUAAGGUUUAAAAAAGUAUUUAUCAUUAUAAACAUACAUACCAUUUGGGAGCAGGUUUAUUAACCUUGAGAGCCAAAGGUUUCCUUAGGCCCUGUAACAUUCAGAACCUUUGGUGUUUCAGGUGGUAUUAUAGCUCAAAUAGUGACAGGACAGGGAAUGCGUUCCAAAGGAAUAUUGGAGCAAUUUUAACAUUGCAGAAACCUGCUCUGGGUGUGUCUCUCUGUAGAGAUAACCUGAUGAUUAUUAAAUGUAAAAUUAAGGCAACUCAUGAAUAUUUUUAUUUACAAAGUGCUUGAAACUCAGCCAAGGAGAGAAAACUAAGUACUUUUAUAUAAUUCAUCACUUUUCUGGCUACAGCAGGACAGAAUAUGACCAUCUUCGUUUGAAGGCACCAAAUCGUCGCAGUGUCUUUGCCAUAAGUUGCAGGGUUAAAUGCGGGAAUCUCUCCUUGCGUUCCUGUCUGGCGUAUUCUGAAGAAAAGAACAGAAUUCUUGUGCCUACCUAAGAAUUUGAGUAGUGUCUAAACAAACAAAGCAGUUAGGUCAUUUUAACUGACUUGAUUAUCCAACUGGUCUUUGACAGAUUUGACUGUUCAUAUUUAGUUUAUGUUUGUCUGAUCAUCCAGUUUGCUUUAUUUUGCUGUGUUUUAUUUUGUUGUUUGUUUUGUUUUGUACCAGUGUACUAAAACUAGUCAAAAUACUUGAAUUAGUUUGUUUGUGCAAAGUGUACAAGCUUAGUAAAGUGUCCAUGAAGCAAUAGCCAUGAAUGCUAAUUAUUUCUAAAUAGGGCCACAUGGUUUUAAACUAAUGAUGGUGAAAGAAAUACGAUGACUGAGAAAGUCAUUUCGCAUGUUUACUAUUGUUAUAUUCGUGCUUUACUUCAAGAGUGCAGAAAUCAUAAUAAAUAACAAACUAUUUUUGUGUUUUCUCAAUGUGACAUUUCUGUUUCUCUCAUUUAUUCGGAUUUUCCUUGUAAAGAAAUUGACAUAUAUUUCAUAUAUAUAUACACAUAUAUAUAUAUACACAUAUAUAUACAUAUAUAUAUAUGAUGUUAAAUUUCCUGCCACUCAUGUGGAGUAAUGAUCUGAAAUUAACAGAUAAUCUGAAGCUAAUUAUAUUCAGACUAUUUCAAGUGCACUGUUUCAGUUGCCCGGGUGGUCCUUACCUCUUGUCCUUGAAAUCCAUGCCAUGCUGAAGCAAGGCAAUACUGUGAUAAAGUAUUUUUUUUAAUAUUUCAAUGGAAUGCUCCAAAUGAUUUAUAAAAAUUUCAAAAUAAAAGAUGGCUUGUAGUAAAUUGUAAAAUAUGAGUAGAACUGAAAUAACCUGUUUCAUUCUUAUUCUAGAUUAAACAAACAUAUACAUAUAACCAUAUAAAUGUUAUUUUUAUUGUCUGAGAGUACUCUUAAAUAUUAGUAUAAAGUGUCAAAAGAAUUGACUGAAUAUAAGUACUGUUAAAAUAAUUUGAACCCUAUGAUAUUUUAAACCAAGAGGCAAAGAUAUCACCUAAAACUUGGUAUUUCUUGAUAGGUUAGGUGCAAUUAGGCAGUGACAAUCUGUAUUCAACAACAUAUAAGAGGAAAGAGUAAUAUCAGAAUUUUGACACAAAUUAAUGUGUCAACAUAUUUUACAAUGAUUGUCAAAGGAAUUUAAGAAUUGUAUUUUUAAAGAUUUAUUUAUUAUUUUUGUGGGCUAAGACAUUGCCAUUCUAUUGAUACUAAUGUCUAACAUUAAUGUUUCUUGUUUUCUUUUAUUUUUAAUAUUAAUAACUAUAAAAGCAUUUUUCAAAGGCUAUUUGAUCCAGCACACUUCAUAUGGAUCUUAGUCUUUGAAUUAAAUAUUUAUAUAAAUAGAUUUUAUUAAUCAAAUUAUUUAUUUGUGUGCCAACAAUUAAUUGUAACUUUAUGAUCAUAUCUUUGUUUAUGCUUCUUAUUUUAAAUAAUUAAGAUGUAUCUGUGCCUUUUAAUUAGCAUGACAGUCUGCUUUAUUAAAAGAAAAAAACUACAAUUAACAUCAUUACUAGUAUAUUUUGCUUAGAUUUGAGAUACUCAAAUGAUGCUGUCUUAUUUACAGUCAGUAAUUAAGUUCAAUUCAAACUAUUUUACCUUGAAUAUAAAAUCUAAAUAUAAUAAACUAUACUGUAUAAUUUACUUUAAUUCAUGUCAAAACAAUUCUUUUUAUACACACACAUGAAAUAUUCUUAAUCUGUUCUGUAUUGUUUUUCUAAACAAUAAAUACAUUCUAGAUAUUGUUGAAAUUAAAUUUUGCCAGUUGUAAGACAAAGACAACAGAUAACUUUUGAAAAUCAAGCAAAUUACUAUGGUGUUUCUUGGGUCUUCAUUAUUCCAUUUAUAUAUAUUUUUUAUUUCGAAUAAUAAAUCAACCUUUAUUUUUGGCAAUAAGAUUAUCACUGACGAAAAUAUGUACAGUUCAAGAAGUAGAAAUAAUAUUUUCCAUUAGUUAAUUUAGGAAAUAUUGGAAUAGCAUAUUAUAAUUAUUUAUGAGGUUCCCAAUGUUGUUUUUCACAGAAAAUAAGGUAAACAUUCAACUUAAAUCCCCCAUGAAGUUUUUUCAUGCUCAUACUCAUAAUCAUUAUCACAUAAUGUGCUUAUUCAACAAACUUUGUAUCUGGAUAUAUUUUUAACAAUAAGUUUGUUAGCAUUAUUUAUUUAUCUUUAGAGAGAAAAUAUUUGCAUCUGUUUAUUUACCCUUUGAAGCAUUAAUACUUAGUCACUCACAUUGAAAUUGCAUAUGGAUGUAUCAACAUAGGCUAAAAUUAAAUUAUGGAUGUCGCAGAAAUGAAAUACUUCAUCUUAGAAGGUAAAAUUUUCAAGAAAGUAUUUUAUUCAUGGACUUAAUAAUGUCUUAAGAUGAAACAAUUUUAUGUCCAAAUGAGAAAUUUAUAAAAAGACCCACAUAUAGUAGUUGCUGAACAAACAUAAUUUUCUUCCAGCUCCCAUCCUUCCUUUUUGAAAAAUUGAAUUUACCCAUGUAGAUGCAGCUAUUUACAAUUAUACAAGAAUGCGAAUAGAUUAAUUAUAUCUUCUCAUAUAAAGGCAAAGAAUUUUAUAUUAUAUAUAAUGCUAAAUAUUUAUUUGAUAACACAAUAUUCUUAGAAAAAUAGUUUAUUACUUUAGGAUUUUAUCUAUAACAUAAAUAUAUUAUUUGUUAUUACCUCUUUAAAUUUUCAUUUUAUACAAUUUUUGAGAUUCUGGCCACACAACAUUCAGAAUUAUUGCUCAUGUAAAUUUAAAUAUUGCUACUUAUUUUUUUUCUUUUCUGAAAUGAAAACAUGAAUCUUUUGGCAUCUGUUUUUAGCCUCCCAUGGAAGACAGUAAGCAAAACCAUCACUGUUGGAGAAUUUCAAAUCACAACCCGACAUAGGAGAGUAGAGAAACAAAGAAAUGAGUGGAUCUAGAAAGGCAAACUGAAUUGCUAUAUUUGGAAUAGCUAAGAAGGACCUGACUUUGAGAAGUGCUAGACCAGGGACUAGGAACGUUGCUUAGAUAAAAAUUAUGGCCGAUUACACUGAUGCGAAGGAGAAAACAGUGUAACACAGAGGAGAAAGUUAACAGAGAUAGAAUCUAUGAUUUAAUUUUGCAAAUAGUUUUUUUAGAGAACAACAUGCAUACUAUAAAAGAAAUGAUACUAUUAAGAACAAACCUACUUGUUCCAACUCUUAAAGAAAUAUUCAUGGUUUAGCAUUUGCCUCUAAACCCUGUUAGAAAUAUGUGAAGUUAGAAAUAAAGGUUUUUUUAAAAAAAAAGCUUUUUUGGUAUGUGAACUGUAUGCUGUGCUCAGUAUGUACUGAAACAUACUAUCUUUUAUUUUCUUUAAUUUAUAUAUUCCAUUCAAAUUCUAUAUUCUUAAGUUAGCUACCACAACGUUUUCUUAUUGUUUCAAUAUGGUAUGUCCCAAUGAAAUGCUGUAUAUAUAUGUCUAAACUGUAAAAAUUAUACUGCAAAUGUUGAAGUUUUGUAUUUAUGAGAGACAUUGAAAGUAUGGCUUACAGUAUAUCAAACUUGUCACACUUCACCAUUUGUAUAUUAAUAGUAAAGAUACUUUUACUUUAA-3'- Poly-A tail
- Coding region
DNA
DNA (Gene ID: 4685)
neural cell adhesion molecule 2
strand +
NCAM21, MGC51008
NCBI CDS gene sequence (2514 bp)
5'-ATGAGCCTCCTCCTCTCCTTCTACCTGCTGGGGTTGCTTGTCAGTAGCGGGCAAGCTCTTCTTCAAGTGACAATTTCACTTAGCAAAGTAGAGCTTAGTGTTGGAGAATCTAAATTCTTCACATGTACAGCGATTGGTGAACCTGAAAGTATAGATTGGTATAATCCTCAAGGAGAGAAGATAATTTCAACACAGAGGGTAGTAGTGCAAAAGGAAGGTGTTAGGTCACGGTTAACCATCTACAATGCAAATATAGAAGATGCAGGGATATATCGTTGTCAAGCAACAGATGCCAAAGGACAAACACAAGAAGCTACAGTAGTTTTGGAAATTTACCAAAAACTCACTTTCAGAGAAGTGGTATCTCCACAAGAATTCAAACAAGGAGAAGATGCAGAAGTGGTTTGCCGAGTTAGCAGTTCACCTGCACCTGCTGTCAGCTGGTTGTATCATAATGAGGAAGTCACCACTATTTCCGACAATCGGTTCGCTATGTTAGCAAACAATAACCTGCAGATTCTCAACATCAATAAAAGTGATGAAGGTATATACAGATGTGAAGGAAGAGTGGAGGCCAGGGGAGAAATTGACTTCCGTGATATCATTGTTATTGTTAATGTGCCGCCAGCAATCTCAATGCCTCAGAAATCTTTTAATGCCACAGCAGAGAGAGGAGAAGAAATGACATTTTCCTGCAGGGCCTCAGGCTCTCCAGAACCCGCCATCTCCTGGTTCAGGAATGGCAAGCTCATTGAAGAAAATGAGAAGTACATATTGAAAGGGAGCAATACAGAACTCACTGTCAGGAACATAATCAATAGTGATGGTGGTCCTTATGTCTGCAGGGCCACAAATAAGGCAGGAGAAGATGAAAAGCAAGCTTTCCTCCAAGTCTTTGTACAGCCTCACATAATACAGCTTAAAAATGAAACTACATATGAGAATGGTCAAGTCACACTCGTATGTGATGCGGAAGGGGAGCCTATTCCAGAAATCACTTGGAAAAGAGCTGTGGATGGCTTCACGTTCACTGAAGGCGATAAGAGCCTGGACGGCCGTATCGAAGTCAAAGGGCAGCATGGAAGCTCATCACTGCATATTAAAGATGTGAAGTTGTCAGATTCAGGGAGATATGACTGTGAAGCTGCAAGCAGAATTGGAGGGCATCAAAAGAGCATGTACCTTGATATTGAATATGCCCCCAAGTTTATATCAAACCAAACAATTTATTACTCTTGGGAAGGAAATCCTATCAATATAAGTTGTGATGTGAAATCGAATCCACCAGCATCAATTCACTGGAGAAGAGATAAATTAGTCTTACCTGCTAAAAACACGACCAATTTAAAGACTTATAGTACAGGAAGAAAGATGATATTAGAGATTGCACCTACATCTGACAATGACTTTGGACGCTATAATTGCACAGCCACTAATCATATAGGAACAAGATTTCAAGAATATATTCTTGCTTTGGCTGACGTGCCATCCAGTCCCTATGGAGTGAAGATCATAGAGCTGTCGCAGACCACGGCCAAGGTTTCCTTCAACAAACCGGACTCCCATGGAGGTGTACCTATTCATCACTATCAGGTGGATGTCAAAGAAGTAGCGTCAGAAATCTGGAAAATTGTACGCTCCCATGGAGTTCAAACAATGGTTGTTTTGAACAACCTGGAACCAAATACAACTTATGAAATCAGGGTTGCAGCTGTAAATGGAAAGGGACAAGGAGACTACAGTAAAATAGAAATCTTCCAAACATTACCAGTTCGTGAACCAAGTCCTCCATCCATACATGGACAGCCAAGCAGTGGAAAGAGCTTTAAACTCAGCATCACCAAACAGGACGATGGAGGGGCCCCTATTTTGGAATACATTGTGAAATATAGAAGTAAAGATAAGGAAGACCAATGGCTAGAGAAAAAAGTGCAAGGAAATAAAGACCACATCATTTTGGAGCATCTCCAGTGGACCATGGGGTATGAAGTTCAGATTACAGCTGCCAATAGATTGGGATATTCTGAACCGACAGTTTATGAATTCAGCATGCCACCAAAGCCCAACATTATTAAAGACACGCTGTTTAATGGTCTTGGGCTTGGAGCAGTAATTGGCCTGGGAGTTGCTGCACTGCTGCTAATTCTTGTGGTAACAGACGTCAGCTGCTTCTTTATTCGGCAATGTGGGTTGCTGATGTGCATCACTAGGAGAATGTGTGGAAAGAAAAGTGGCTCCAGTGGCAAAAGTAAAGAACTCGAAGAAGGAAAAGCTGCATACCTGAAAGATGGATCAAAAGAACCAATAGTGGAGATGAGAACAGAGGATGAAAGAGTTACTAATCACGAAGATGGGAGCCCAGTAAATGAGCCAAATGAAACCACACCACTGACAGAACCTGAAAAATTGCCTTTAAAGGAAGAAGATGGGAAAGAAGCTCTAAATCCAGAAACTATAGAAATTAAAGTTTCTAACGACATCATTCAATCAAAAGAAGACGACAGCAAAGCATAA-3'
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