Q05097 protein in UniLectin3D

Reference of
7Z62 structure
2023
PubMed

Bruneau A, Gillon E, Furiga A, Brachet E, Alami M, Roques C, Varrot A, Imberty A, Messaoudi S.
Discovery of potent 1,1-diarylthiogalactoside glycomimetic inhibitors of Pseudomonas aeruginosa LecA with antibiofilm properties. European journal of medicinal chemistry 2023

Reference of
7Z63 structure
2023
PubMed

Bruneau A, Gillon E, Furiga A, Brachet E, Alami M, Roques C, Varrot A, Imberty A, Messaoudi S.
Discovery of potent 1,1-diarylthiogalactoside glycomimetic inhibitors of Pseudomonas aeruginosa LecA with antibiofilm properties. European journal of medicinal chemistry 2023

Reference of
7FIO structure
2022
PubMed

Siebs E, Shanina E, Kuhaudomlarp S, da Silva Figueiredo Celestino Gomes P, Fortin C, Seeberger P, Rognan D, Rademacher C, Imberty A, Titz A.
Targeting the Central Pocket of the Pseudomonas aeruginosa Lectin LecA. Chembiochem : a European journal of chemical biology 2022

Reference of
7FJH structure
2022
PubMed

Elena Shanina, Sakonwan Kuhaudomlarp, Eike Siebs, Felix F. Fuchsberger, Maxime Denis, Priscila da Silva Figueiredo Celestino Gomes Mads H. Clausen, Peter H. Seeberger, Didier Rognan, Alexander Titz, Anne Imberty; Christoph Rademache
Targeting undruggable carbohydrate recognition sites through focused fragment library design Communications Chemistry 2022

Reference of
6YO3 structure
2021
PubMed

Kuhaudomlarp S, Siebs E, Shanina E, Topin J, Joachim I, da Silva Figueiredo Celestino Gomes P, Varrot A, Rognan D, Rademacher C, Imberty A, Titz A.
Non-Carbohydrate Glycomimetics as Inhibitors of Calcium(II)-Binding Lectins. Angewandte Chemie (International ed. in English) 2021

Reference of
6YOH structure
2021
PubMed

Kuhaudomlarp S, Siebs E, Shanina E, Topin J, Joachim I, da Silva Figueiredo Celestino Gomes P, Varrot A, Rognan D, Rademacher C, Imberty A, Titz A.
Non-Carbohydrate Glycomimetics as Inhibitors of Calcium(II)-Binding Lectins. Angewandte Chemie (International ed. in English) 2021

Reference of
5MIH structure
2017
PubMed

Wagner S, Hauck D, Hoffmann M, Sommer R, Joachim I, Müller R, Imberty A, Varrot A, Titz A.
Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging. Angewandte Chemie (International ed. in English) 2017

Reference of
5D21 structure
2016
PubMed

Bergmann, M., Michaud, G., Visini, R., Jin, X., Gillon, E., Stocker, A., Imberty, A., Darbre, T., Reymond, J.L.
Multivalency effects on Pseudomonas aeruginosa biofilm inhibition and dispersal by glycopeptide dendrimers targeting lectin LecA. 2016

Reference of
4YW6 structure
2015
PubMed

Visini R, Jin X, Bergmann M, Michaud G, Pertici F, Fu O, Pukin A, Branson TR, Thies-Weesie DM, Kemmink J, Gillon E, Imberty A, Stocker A, Darbre T, Pieters RJ, Reymond JL.
Structural Insight into Multivalent Galactoside Binding to Pseudomonas aeruginosa Lectin LecA. ACS Chem. Biol. 2015

Reference of
4YW7 structure
2015
PubMed

Visini R, Jin X, Bergmann M, Michaud G, Pertici F, Fu O, Pukin A, Branson TR, Thies-Weesie DM, Kemmink J, Gillon E, Imberty A, Stocker A, Darbre T, Pieters RJ, Reymond JL.
Structural Insight into Multivalent Galactoside Binding to Pseudomonas aeruginosa Lectin LecA. ACS Chem. Biol. 2015

Reference of
4YWA structure
2015
PubMed

Visini R, Jin X, Bergmann M, Michaud G, Pertici F, Fu O, Pukin A, Branson TR, Thies-Weesie DM, Kemmink J, Gillon E, Imberty A, Stocker A, Darbre T, Pieters RJ, Reymond JL.
Structural Insight into Multivalent Galactoside Binding to Pseudomonas aeruginosa Lectin LecA. ACS Chem. Biol. 2015

Reference of
4AL9 structure
2014
PubMed

Blanchard, B., Imberty, A., Varrot, A.
Secondary sugar binding site identified for LecA lectin from Pseudomonas aeruginosa. Proteins 2014

Reference of
4CPB structure
2014
PubMed

Novoa A, Eierhoff T, Topin J, Varrot A, Barluenga S, Imberty A, Römer W, Winssinger N.
A LecA ligand identified from a galactoside-conjugate array inhibits host cell invasion by Pseudomonas aeruginosa. Angewandte Chemie (International ed. in English) 2014

Reference of
4CP9 structure
2014
PubMed

Novoa A, Eierhoff T, Topin J, Varrot A, Barluenga S, Imberty A, Römer W, Winssinger N.
A LecA ligand identified from a galactoside-conjugate array inhibits host cell invasion by Pseudomonas aeruginosa. Angewandte Chemie (International ed. in English) 2014

Reference of
4A6S structure
2013
PubMed

Rodrigue J, Ganne G, Blanchard B, Saucier C, Giguère D, Shiao T, Varrot A, Imberty A, Roy R.
Aromatic thioglycoside inhibitors against the virulence factor LecA from Pseudomonas aeruginosa. Organic & biomolecular chemistry 2013

Reference of
4LJH structure
2013
PubMed

Kadam R, Garg D, Schwartz J, Visini R, Sattler M, Stocker A, Darbre T, Reymond J.
CH-pi T-shape interaction with histidine explains binding of aromatic galactosides to Pseudomonas aeruginosa lectin LecA. ACS chemical biology 2013

Reference of
4LK6 structure
2013
PubMed

Kadam R, Garg D, Schwartz J, Visini R, Sattler M, Stocker A, Darbre T, Reymond J.
CH-pi T-shape interaction with histidine explains binding of aromatic galactosides to Pseudomonas aeruginosa lectin LecA. ACS chemical biology 2013

Reference of
4LK7 structure
2013
PubMed

Kadam R, Garg D, Schwartz J, Visini R, Sattler M, Stocker A, Darbre T, Reymond J.
CH-pi T-shape interaction with histidine explains binding of aromatic galactosides to Pseudomonas aeruginosa lectin LecA. ACS chemical biology 2013

Reference of
3ZYB structure
2011
PubMed

Kadam R, Bergmann M, Hurley M, Garg D, Cacciarini M, Swiderska M, Nativi C, Sattler M, Smyth A, Williams P, Cámara M, Stocker A, Darbre T, Reymond J.
A glycopeptide dendrimer inhibitor of the galactose-specific lectin LecA and of Pseudomonas aeruginosa biofilms. Angewandte Chemie (International ed. in English) 2011

Reference of
3ZYF structure
2011
PubMed

Kadam R, Bergmann M, Hurley M, Garg D, Cacciarini M, Swiderska M, Nativi C, Sattler M, Smyth A, Williams P, Cámara M, Stocker A, Darbre T, Reymond J.
A glycopeptide dendrimer inhibitor of the galactose-specific lectin LecA and of Pseudomonas aeruginosa biofilms. Angewandte Chemie (International ed. in English) 2011

Reference of
3ZYH structure
2011
PubMed

Kadam R, Bergmann M, Hurley M, Garg D, Cacciarini M, Swiderska M, Nativi C, Sattler M, Smyth A, Williams P, Cámara M, Stocker A, Darbre T, Reymond J.
A glycopeptide dendrimer inhibitor of the galactose-specific lectin LecA and of Pseudomonas aeruginosa biofilms. Angewandte Chemie (International ed. in English) 2011

Reference of
2WYF structure
2010
PubMed

Nurisso A, Blanchard B, Audfray A, Rydner L, Oscarson S, Varrot A, Imberty A.
Role of water molecules in structure and energetics of Pseudomonas aeruginosa lectin I interacting with disaccharides. J. Biol. Chem. 2010

Reference of
2VXJ structure
2008
PubMed

Blanchard B, Nurisso A, Hollville E, Tétaud C, Wiels J, Pokorná M, Wimmerová M, Varrot A, Imberty A.
Structural basis of the preferential binding for globo-series glycosphingolipids displayed by Pseudomonas aeruginosa lectin I. Journal of molecular biology 2008

Reference of
1L7L structure
2003
PubMed

Karaveg K, Liu Z, Tempel W, Doyle R, Rose J, Wang B.
Crystallization and preliminary X-ray diffraction analysis of lectin-1 from Pseudomonas aeruginosa. Acta crystallographica. Section D, Biological crystallography 2003

Reference of
1OKO structure
2003
PubMed

Cioci G, Mitchell EP, Gautier C, Wimmerova M, Sudakevitz D, Perez S, Gilboa-Garber N, Imberty A
Structural basis of calcium and galactose recognition by the lectin PA-IL of Pseudomonas aeruginosa FEBS Lett. 2003

Reference of
1UOJ structure
2003
PubMed

Cioci G, Mitchell EP, Gautier C, Wimmerova M, Sudakevitz D, Perez S, Gilboa-Garber N, Imberty A
Structural basis of calcium and galactose recognition by the lectin PA-IL of Pseudomonas aeruginosa FEBS Lett. 2003

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