P01556 protein in UniLectin3D

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Class

Family

Origin

Species

Available structures

1CHP : no ligand 1CHQ : no ligand 1CT1 : bGal13bGalNAc14(aNeuAc23)bGal1 1FGB : no ligand 1G8Z : Gal 1XTC : no ligand 2CHB : bGal13bGalNAc14(aNeuAc23)bGal1 3CHB : bGal13bGalNAc14(aNeuAc23)bGal1 3EFX : A Lewis Y analog 5ELC : (aFuc 12) bGal 14 (aFuc 13) Gl 5ELE : aGalNAc 13 (aFuc 12) bGal 14 (5ELF : aGalNAc 13 (aFuc 12) bGal 14 (5LZG : Inhibitor PC262 5LZJ : Inhibitor Laura237 6HJD : bGal 14 (aFuc 13) GlcNAc 6HMW : Fuc 6HMY : Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)

Related proteins
> 50% identity

ProtVista PDB viewer

Reference of
6HMW structure
2019
PubMed

Heim J, Hodnik V, Heggelund J, Anderluh G, Krengel U.
Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site. Scientific reports 2019

Reference of
6HJD structure
2019
PubMed

Heim J, Hodnik V, Heggelund J, Anderluh G, Krengel U.
Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site. Scientific reports 2019

Reference of
6HMY structure
2019
PubMed

Heim J, Hodnik V, Heggelund J, Anderluh G, Krengel U.
Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site. Scientific reports 2019

Reference of
5LZG structure
2017
PubMed

Heggelund J, Mackenzie A, Martinsen T, Heim J, Cheshev P, Bernardi A, Krengel U.
Towards new cholera prophylactics and treatment: Crystal structures of bacterial enterotoxins in complex with GM1 mimics. Scientific reports 2017

Reference of
5LZJ structure
2017
PubMed

Reference of
5ELC structure
2016
PubMed

Heggelund J, Burschowsky D, Bjørnestad V, Hodnik V, Anderluh G, Krengel U.
High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence. PLoS pathogens 2016

Reference of
5ELE structure
2016
PubMed

Heggelund J, Burschowsky D, Bjørnestad V, Hodnik V, Anderluh G, Krengel U.
High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence. PLoS pathogens 2016

Reference of
5ELF structure
2016
PubMed

Heggelund J, Burschowsky D, Bjørnestad V, Hodnik V, Anderluh G, Krengel U.
High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence. PLoS pathogens 2016

Reference of
3EFX structure
2004
PubMed

Holmner A, Lebens M, Teneberg S, Angstrom J, Okvist M, Krengel U.
Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin: 1.9 A crystal structure reveals the details Structure 2004

Reference of
1G8Z structure
2001
PubMed

Aman, A.T., Fraser, S., Merritt, E.A., Rodigherio, C., Kenny, M., Ahn, M., Hol, W.G., Williams, N.A., Lencer, W.I., Hirst, T.R.
A mutant cholera toxin B subunit that binds GM1- ganglioside but lacks immunomodulatory or toxic activity Proc. Nat. Acad. Sci. USA 2001

Reference of
3CHB structure
1998
PubMed

Merritt, E.A., Kuhn, P., Sarfaty, S., Erbe, J.L., Holmes, R.K., Hol, W.G.
The 1.25 A resolution refinement of the cholera toxin B-pentamer: evidence of peptide backbone strain at the receptor-binding site J. Mol. Biol. 1998

Reference of
1CT1 structure
1997
PubMed

Merritt, E.A., Sarfaty, S., Jobling, M.G., Chang, T., Holmes, R.K., Hirst, T.R., Hol, W.G.
Structural studies of receptor binding by cholera toxin mutants Protein Sci. 1997

Reference of
2CHB structure
1997
PubMed

Merritt, E.A., Sarfaty, S., Jobling, M.G., Chang, T., Holmes, R.K., Hirst, T.R., Hol, W.G.
Structural studies of receptor binding by cholera toxin mutants Protein Sci. 1997

Reference of
1CHP structure
1995
PubMed

Merritt E, Sarfaty S, Chang T, Palmer L, Jobling M, Holmes R, Hol W.
Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants. Structure (London, England : 1993) 1995

Reference of
1CHQ structure
1995
PubMed

Reference of
1FGB structure
1995
PubMed

Zhang, R.G., Westbrook, M.L.,Westbrook, E.M., Scott, D.L., Otwinowski, Z., Maulik, P.R., Reed, R.A., Shipley, G.G.
The 2.4 A crystal structure of cholera toxin B subunit pentamer: choleragenoid J. Mol. Biol. 1995

Reference of
1XTC structure
1995
PubMed

Zhang, R.G., Scott, D.L., Westbrook, M.L., Nance, S., Spangler, B.D., Shipley, G.G., Westbrook, E.M.
The three-dimensional crystal structure of cholera toxin J. Mol. Biol. 1995

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