P02866Uniprot
Fold
Class
Family
Origin
Species
Available structures
1APN : no ligand1BXH : aMan12aManOMe1C57 : no ligand1CES : no ligand1CJP : aDGlc derivative1CN1 : no ligand1CON : no ligand1CVN : aMan13(aMan16)Man1DQ0 : no ligand1DQ1 : no ligand1DQ2 : no ligand1DQ4 : no ligand1DQ5 : no ligand1DQ6 : no ligand1ENQ : no ligand1ENR : no ligand1ENS : no ligand1GIC : aGlcOMe1GKB : no ligand1HQW : Tripeptide YPY1I3H : aMan12Man1JBC : no ligand1JN2 : meso-tetra(4-sulfonatophenyl)p1JOJ : Met-Tyr-Trp-Tyr-Pro-Tyr1JUI : MYWYPYASGS1JW6 : Met-Tyr-Trp-Tyr-Pro-Tyr1JYC : RVWYPYGSYLTASGS1JYI : DVFYPYPYASGS1NLS : no ligand1NXD : no ligand1ONA : aMan13(aMan16)Man1QGL : Divalent mannoside1QNY : no ligand1SCR : no ligand1SCS : no ligand1TEI : bGlcNAc12aMan13(bGlcNAc12aMan11VAL : aGlc-nitrophenyl1VAM : aMan-nitrophenyl1XQN : no ligand2CNA : no ligand2CTV : no ligand2ENR : no ligand2UU8 : no ligand3CNA : no ligand3D4K : synthetic analog of trimannosi3ENR : no ligand4PF5 : no ligand5CNA : aManOMe5WEY : aMan 12 Man
Related proteins
> 50% identity
> 50% identity
PubMed
Gerlits O, Coates L, Woods R, Kovalevsky A.
Mannobiose Binding Induces Changes in Hydrogen Bonding and Protonation States of Acidic Residues in Concanavalin A As Revealed by Neutron Crystallography. Biochemistry 2017
Mannobiose Binding Induces Changes in Hydrogen Bonding and Protonation States of Acidic Residues in Concanavalin A As Revealed by Neutron Crystallography. Biochemistry 2017
PubMed
François-Heude M, Méndez-Ardoy A, Cendret V, Lafite P, Daniellou R, Ortiz Mellet C, García Fernández J, Moreau V, Djedaïni-Pilard F.
Synthesis of high-mannose oligosaccharide analogues through click chemistry: true functional mimics of their natural counterparts against lectins Chemistry (Weinheim an der Bergstrasse, Germany) 2015
Synthesis of high-mannose oligosaccharide analogues through click chemistry: true functional mimics of their natural counterparts against lectins Chemistry (Weinheim an der Bergstrasse, Germany) 2015
PubMed
Kadirvelraj, R., Foley, B.L., Dyekjaer, J.D., Woods, R.J.
Involvement of water in carbohydrate-protein binding: concanavalin A revisited J. Am. Chem. Soc. 2008
Involvement of water in carbohydrate-protein binding: concanavalin A revisited J. Am. Chem. Soc. 2008
PubMed
Ahmed H, Blakeley M, Cianci M, Cruickshank D, Hubbard J, Helliwell J.
The determination of protonation states in proteins. Acta crystallographica. Section D, Biological crystallography 2007
The determination of protonation states in proteins. Acta crystallographica. Section D, Biological crystallography 2007
PubMed
Lopez-Jaramillo FJ, Gonzalez-Ramirez LA, Albert A, Santoyo-Gonzalez F, Vargas-Berenguel A, Otalora F
Structure of concanavalin A at pH 8: bound solvent and crystal contacts Acta Crystallogr. D 2004
Structure of concanavalin A at pH 8: bound solvent and crystal contacts Acta Crystallogr. D 2004
PubMed
Blakeley MP, Kalb AJ, Helliwell JR, Myles DA.
The 15-K neutron structure of saccharide-free concanavalin A Proc. Nat. Acad. Sci. USA 2004
The 15-K neutron structure of saccharide-free concanavalin A Proc. Nat. Acad. Sci. USA 2004
PubMed
Kantardjieff, K., Hochtl, P., Segelke, B.W., Tao, F.M., Rupp, B.
Concanavalin A in a dimeric crystal form: revisiting structural accuracy and molecular flexibility Acta Crystallogr. 2002
Concanavalin A in a dimeric crystal form: revisiting structural accuracy and molecular flexibility Acta Crystallogr. 2002
PubMed
Zhang Z, Qian M, Huang Q, Jia Y, Tang Y, Wang K, Cui D, Li M
Crystal structure of the complex of concanavalin A and tripeptide J. Protein Chem. 2001
Crystal structure of the complex of concanavalin A and tripeptide J. Protein Chem. 2001
PubMed
Sanders, D.A., Moothoo, D.N., Raftery, J., Howard, A.J., Helliwell, J.R., Naismith, J.H.
The 1.2 A resolution structure of the Con A-dimannose complex J. Mol. Biol. 2001
The 1.2 A resolution structure of the Con A-dimannose complex J. Mol. Biol. 2001
PubMed
Goel M, Jain D, Kaur KJ, Kenoth R, Maiya BG, Swamy MJ, Salunke DM
Functional equality in the absence of structural similarity: an added dimension to molecular mimicry J. Biol. Chem. 2001
Functional equality in the absence of structural similarity: an added dimension to molecular mimicry J. Biol. Chem. 2001
PubMed
Jain, D., Kaur, K.J., Salunke, D.M.
Enhanced binding of a rationally designed peptide ligand of concanavalin a arises from improved geometrical complementarity Biochemistry 2001
Enhanced binding of a rationally designed peptide ligand of concanavalin a arises from improved geometrical complementarity Biochemistry 2001
PubMed
Jain D, Kaur KJ, Salunke DM
Plasticity in protein-peptide recognition: crystal structures of two different peptides bound to concanavalin A Biophys. J. 2001
Plasticity in protein-peptide recognition: crystal structures of two different peptides bound to concanavalin A Biophys. J. 2001
PubMed
Zhang, Z., Qian, M., Huang, Q., Jia, Y., Tang, Y.
Crystal structure of the complex of concanacalin A and hexapeptide J. Protein Chem. 2001
Crystal structure of the complex of concanacalin A and hexapeptide J. Protein Chem. 2001
PubMed
Jain D, Kaur KJ, Salunke DM
Plasticity in protein-peptide recognition: crystal structures of two different peptides bound to concanavalin A Biophys. J. 2001
Plasticity in protein-peptide recognition: crystal structures of two different peptides bound to concanavalin A Biophys. J. 2001
PubMed
Habash J, Raftery J, Nuttall R, Price H, Wilkinson C, Kalb A, Helliwell J.
Direct determination of the positions of the deuterium atoms of the bound water in -concanavalin A by neutron Laue crystallography. Acta crystallographica. Section D, Biological crystallography 2000
Direct determination of the positions of the deuterium atoms of the bound water in -concanavalin A by neutron Laue crystallography. Acta crystallographica. Section D, Biological crystallography 2000
PubMed
Bouckaert J, Dewallef Y, Poortmans F, Wyns L, Loris R.
The structural features of concanavalin A governing non-proline peptide isomerization. The Journal of biological chemistry 2000
The structural features of concanavalin A governing non-proline peptide isomerization. The Journal of biological chemistry 2000
PubMed
Bouckaert J, Dewallef Y, Poortmans F, Wyns L, Loris R.
The structural features of concanavalin A governing non-proline peptide isomerization. The Journal of biological chemistry 2000
The structural features of concanavalin A governing non-proline peptide isomerization. The Journal of biological chemistry 2000
PubMed
Bouckaert J, Dewallef Y, Poortmans F, Wyns L, Loris R.
The structural features of concanavalin A governing non-proline peptide isomerization. The Journal of biological chemistry 2000
The structural features of concanavalin A governing non-proline peptide isomerization. The Journal of biological chemistry 2000
PubMed
Bouckaert J, Dewallef Y, Poortmans F, Wyns L, Loris R.
The structural features of concanavalin A governing non-proline peptide isomerization. The Journal of biological chemistry 2000
The structural features of concanavalin A governing non-proline peptide isomerization. The Journal of biological chemistry 2000
PubMed
Bouckaert J, Dewallef Y, Poortmans F, Wyns L, Loris R.
The structural features of concanavalin A governing non-proline peptide isomerization. The Journal of biological chemistry 2000
The structural features of concanavalin A governing non-proline peptide isomerization. The Journal of biological chemistry 2000
PubMed
Bouckaert J, Dewallef Y, Poortmans F, Wyns L, Loris R.
The structural features of concanavalin A governing non-proline peptide isomerization. The Journal of biological chemistry 2000
The structural features of concanavalin A governing non-proline peptide isomerization. The Journal of biological chemistry 2000
PubMed
Jain D, Kaur K, Sundaravadivel B, Salunke DM
Structural and functional consequences of peptide-carbohydrate mimicry. Crystal structure of a carbohydrate-mimicking peptide bound to concanavalin A J. Biol. Chem. 2000
Structural and functional consequences of peptide-carbohydrate mimicry. Crystal structure of a carbohydrate-mimicking peptide bound to concanavalin A J. Biol. Chem. 2000
PubMed
Habash J, Raftery J, Nuttall R, Price H, Wilkinson C, Kalb A, Helliwell J.
Direct determination of the positions of the deuterium atoms of the bound water in -concanavalin A by neutron Laue crystallography. Acta crystallographica. Section D, Biological crystallography 2000
Direct determination of the positions of the deuterium atoms of the bound water in -concanavalin A by neutron Laue crystallography. Acta crystallographica. Section D, Biological crystallography 2000
PubMed
Bouckaert, J., Loris, R., Wyns, L.
Zinc/calcium- and cadmium/cadmium-substituted concanavalin A: interplay of metal binding, pH and molecular packing. Acta Crystallogr. 2000
Zinc/calcium- and cadmium/cadmium-substituted concanavalin A: interplay of metal binding, pH and molecular packing. Acta Crystallogr. 2000
PubMed
Bouckaert, J., Loris, R., Wyns, L.
Zinc/calcium- and cadmium/cadmium-substituted concanavalin A: interplay of metal binding, pH and molecular packing. Acta. Crystallogr. 2000
Zinc/calcium- and cadmium/cadmium-substituted concanavalin A: interplay of metal binding, pH and molecular packing. Acta. Crystallogr. 2000
PubMed
Moothoo, D.N., Canan, B., Field, R.A., Naismith, J.H.
Man alpha1-2 Man alpha-OMe-concanavalin A complex reveals a balance of forces involved in carbohydrate recognition Glycobiology 1999
Man alpha1-2 Man alpha-OMe-concanavalin A complex reveals a balance of forces involved in carbohydrate recognition Glycobiology 1999
PubMed
Dimick, S.M., Powell, S.C., McMahon, S.A., Moothoo, D.N., Naismith, J.H., Toone, E.J.
On the meaning of affinity: Cluster glycoside effects and concanavalin A J. Am. Chem. Soc. 1999
On the meaning of affinity: Cluster glycoside effects and concanavalin A J. Am. Chem. Soc. 1999
PubMed
Moothoo, D.N., Naismith, J.H.
Concanavalin A distorts the b-GlcNac-(1-2)-Man linkage of b-GlcNac-(1-2)-a-Man-(1-3)-[b-GlcNac-(1-2)-a-Man-(1-6)] upon binding Glycobiology 1998
Concanavalin A distorts the b-GlcNac-(1-2)-Man linkage of b-GlcNac-(1-2)-a-Man-(1-3)-[b-GlcNac-(1-2)-a-Man-(1-6)] upon binding Glycobiology 1998
PubMed
Hamodrakas, S.J., Kanellopoulos, P.N., Pavlou, K., Tucker, P.A.
The crystal structure of the complex of concanavalin A with 4'-methylumbelliferyl-a-D-glucopyranoside J. Struct. Biol. 1997
The crystal structure of the complex of concanavalin A with 4'-methylumbelliferyl-a-D-glucopyranoside J. Struct. Biol. 1997
PubMed
Deacon, A.M., Gleichmann, T., Helliwell, J.R., Kalb(Gilboa), A.J.
The structure of concanavalin A and its bound solvent determined with small-molecule accuracy at 0.94A resolution Faraday Trans. 1997
The structure of concanavalin A and its bound solvent determined with small-molecule accuracy at 0.94A resolution Faraday Trans. 1997
PubMed
Bouckaert, J., Poortmans, F., Wyns, L., Loris, R.,
Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A. J. Biol. Chem. 1996
Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A. J. Biol. Chem. 1996
PubMed
Naismith, J.H., Field, R.A.
Structural basis of trimannoside recognition by concanavalin A J. Biol. Chem. 1996
Structural basis of trimannoside recognition by concanavalin A J. Biol. Chem. 1996
PubMed
Bouckaert, J., Poortmans, F., Wyns, L., Loris, R.
Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A J. Biol. Chem. 1996
Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A J. Biol. Chem. 1996
PubMed
Bouckaert, J., Poortmans, F., Wyns, L., Loris, R.
Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A J. Biol. Chem. 1996
Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A J. Biol. Chem. 1996
PubMed
Bouckaert, J., Poortmans, F., Wyns, L., Loris, R.
Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A J. Biol. Chem. 1996
Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A J. Biol. Chem. 1996
PubMed
Harrop S, Helliwell J, Wan T, Kalb A, Tong L, Yariv J.
Structure solution of a cubic crystal of concanavalin A complexed with methyl alpha-D-glucopyranoside. Acta crystallographica. Section D, Biological crystallography 1996
Structure solution of a cubic crystal of concanavalin A complexed with methyl alpha-D-glucopyranoside. Acta crystallographica. Section D, Biological crystallography 1996
PubMed
Parkin S, Rupp B, Hope H.
Atomic resolution structure of concanavalin A at 120 K. Acta crystallographica. Section D, Biological crystallography 1996
Atomic resolution structure of concanavalin A at 120 K. Acta crystallographica. Section D, Biological crystallography 1996
PubMed
Loris, R., Maes, D., Poortmans, F., Wyns, L., Bouckaert, J.
A structure of the complex between concanavalin A and Methyl-3,6-di-O-(a-D-mannopyranosyl)-a-D-mannopyranoside reveals two binding modes, J. Biol. Chem. 1996
A structure of the complex between concanavalin A and Methyl-3,6-di-O-(a-D-mannopyranosyl)-a-D-mannopyranoside reveals two binding modes, J. Biol. Chem. 1996
PubMed
Kanellopolous, P.N., Pavlou, K., Perrakis, A., Agianian, B., Vorgias, C.E., Mavrommatis, C., Soufi, M., Tucker, P.A., Hamodrakas, S.J.
The crystal structure of the complexes of concanavalin A with 4'-nitrophenyl-a-D-mannopyranoside and 4'-nitrophenyl-a-D-glucopyranoside J. Struct. Biol. 1996
The crystal structure of the complexes of concanavalin A with 4'-nitrophenyl-a-D-mannopyranoside and 4'-nitrophenyl-a-D-glucopyranoside J. Struct. Biol. 1996
PubMed
Kanellopolous, P.N., Pavlou, K., Perrakis, A., Agianian, B., Vorgias, C.E., Mavrommatis, C., Soufi, M., Tucker, P.A., Hamodrakas, S.J.
The crystal structure of the complexes of concanavalin A with 4'-nitrophenyl-a-D-mannopyranoside and 4'-nitrophenyl-a-D-glucopyranoside J. Struct. Biol. 1996
The crystal structure of the complexes of concanavalin A with 4'-nitrophenyl-a-D-mannopyranoside and 4'-nitrophenyl-a-D-glucopyranoside J. Struct. Biol. 1996
PubMed
Bouckaert, J., Loris, R., Poortmans, F., Wyns, L.,
The crystallographic structure of metal free concanavalin A at 2.5 angstroms resolution Proteins Struct. Funct. Genet. 1995
The crystallographic structure of metal free concanavalin A at 2.5 angstroms resolution Proteins Struct. Funct. Genet. 1995
PubMed
Emmerich, C., Helliwell, J.R., Redsha, M., Naismith, J.H., Harrop, S.J., Raftery, J., Kalb, A.J. (Gilboa), Yariv, J., Dauter, Z., Wilson, K.S.
High resolution structures of single-metal-substituted concanavalin A : The, Co,Ca-protein at 1.6 A resolution and the Ni,Ca-protein at 2.0 A. Acta. Crystallogr. 1994
High resolution structures of single-metal-substituted concanavalin A : The, Co,Ca-protein at 1.6 A resolution and the Ni,Ca-protein at 2.0 A. Acta. Crystallogr. 1994
PubMed
Emmerich, C., Helliwell, J.R., Redsha, M., Naismith, J.H., Harrop, S.J., Raftery, J., Kalb, A.J. (Gilboa), Yariv, J., Dauter, Z., Wilson, K.S.
High resolution structures of single-metal-substituted concanavalin A : The, Co,Ca-protein at 1.6 A resolution and the Ni,Ca-protein at 2.0 A. Acta. Crystallogr. 1994
High resolution structures of single-metal-substituted concanavalin A : The, Co,Ca-protein at 1.6 A resolution and the Ni,Ca-protein at 2.0 A. Acta. Crystallogr. 1994
PubMed
Naismith, J.H., Emmerich, C., Habash, J., Harrop, S.J., Helliwell, J.R., Hunter, W.N., Raftery, J., Kalb, A.J. (Gilboa), Yariv, J.
Refined structure of concanavalin A complexed with methyl a-D-mannopyranoside at 2.0 A resolution and comparison with the saccharide-free structure Acta. Crystallogr. 1994
Refined structure of concanavalin A complexed with methyl a-D-mannopyranoside at 2.0 A resolution and comparison with the saccharide-free structure Acta. Crystallogr. 1994
PubMed
Naismith J, Habash J, Harrop S, Helliwell J, Hunter W, Wan T, Weisgerber S, Kalb A, Yariv J.
Refined structure of cadmium-substituted concanavalin A at 2.0 A resolution. Acta crystallographica. Section D, Biological crystallography 1993
Refined structure of cadmium-substituted concanavalin A at 2.0 A resolution. Acta crystallographica. Section D, Biological crystallography 1993
PubMed
Weisgerber, S., Helliwell, J.R.
High resolution crystallographic studies of native concanavalin A using rapid Laue data collection methods and the introduction of a monochromatic large-angle oscillation technique (LOT) J. Chem. Soc. Faraday Trans. 1993
High resolution crystallographic studies of native concanavalin A using rapid Laue data collection methods and the introduction of a monochromatic large-angle oscillation technique (LOT) J. Chem. Soc. Faraday Trans. 1993
PubMed
Shoham, M., Yonath, A., Sussman, J.L., Moult, J., Traub, W., Kalb, A.J. (Gilboa),
Crystal structure of demetallized concanavalin A. The metal binding region J. Mol. Biol. 1979
Crystal structure of demetallized concanavalin A. The metal binding region J. Mol. Biol. 1979
PubMed
Reeke Jr, G.N., Becker, J.W., Edelman, G.M.
The covalent and three-dimensional structure of concanavalin A. Atomic coordinates, hydrogen bonding and quaternary structure J. Biol. Chem. 1975
The covalent and three-dimensional structure of concanavalin A. Atomic coordinates, hydrogen bonding and quaternary structure J. Biol. Chem. 1975
PubMed
Hardman, K. D. & Ainsworth, C. F.
Structure of concanavalin A at 2.4 angstroms Biochemistry 1972
Structure of concanavalin A at 2.4 angstroms Biochemistry 1972
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