NCBI Summary
CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis (Kato et al., 2007 [PubMed 17947679]).[supplied by OMIM, Aug 2008].
Protein
Protein (NP_055695)
CD302
CD302 antigen (C-type lectin BIMLEC) (C-type lectin domain family 13 member A) (DEC205-associated C-type lectin 1) (Type I transmembrane C-type lectin receptor DCL-1) (CD antigen CD302)
CD302
CD302 molecule
CD302
Very low evidence
C-type lectin
Undefined
C-type - CTLD/acidic neck
a/b mixed / C-type lectin-like
Uncharacterised
NP_055695
9936
Q8IX05
ENSP00000259053.4
Q8IX05
0.276
10.4049/jimmunol.179.9.6052
neXtProt, PFAM, InterPro
Protein sequence and protein families (fasta) (232 amino acids) Download
MLRAALPALLLPLLGLAAAAVADCPSSTWIQFQDSCYIFLQEAIKVESIEDVRNQCTDHGADMISIHNEEENAFILDTLKKQWKGPDDILLGMFYDTDDASFKWFDNSNMTFDKWTDQDDDEDLVDTCAFLHIKTGEWKKGNCEVSSVEGTLCKTAIPYKRKYLSDNHILISALVIASTVILTVLGAIIWFLYKKHSDSRFTTVFSTAPQSPYNEDCVLVVGEENEYPVQFD
Mol* PDB structure viewerUniLectin3D
Structural models
AlphaFold v2: AF-Q8IX05-F1Download
  Model Confidence:
  •    Very high (pLDDT > 90)
  •    Confident (90 > pLDDT > 70)
  •    Low (70 > pLDDT > 50)
  •    Very low (pLDDT < 50)

  AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Ligand
Glycan ligands from structural data
No crystal structures of complexes with glycan ligand.
Expression
Human Protein Atlas
GeneCards
mRNA expression in normal human tissues for CD302 Gene
References
NCBI References (7 PubMed Identifiers)
  • A reference map of the human binary protein interactome. [32296183]
  • Characterization of the Expression and Function of the C-Type Lectin Receptor CD302 in Mice and Humans Reveals a Role in Dendritic Cell Migration. [27316686]
  • New genetic associations detected in a host response study to hepatitis B vaccine. [20237496]
  • Defining the membrane proteome of NK cells. [19946888]
  • Characterization of DLC1-SAM equilibrium unfolding at the amino acid residue level. [19317456]
  • The novel endocytic and phagocytic C-Type lectin receptor DCL-1/CD302 on macrophages is colocalized with F-actin, suggesting a role in cell adhesion and migration. [17947679]
  • Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1. [12824192]
UniProt Main References (5 PubMed Identifiers)
  • Complete sequencing and characterization of 21,243 full-length human cDNAs. [14702039]
  • Generation and annotation of the DNA sequences of human chromosomes 2 and 4. [15815621]
  • Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. [7584026]
  • The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). [15489334]
  • 1H, 13C and 15N resonance assignments of human DCL-1 (CD302) extracellular domain. [26725057]
All isoforms of this gene containing a lectin domain
NP_055695.2, NP_001185693.1, NP_001185692.1
RNA
RNA (Transcript ID: NM_014880.5)
NM_014880.5
CD302 molecule, transcript variant 1
All isoforms of CD302 containing a lectin domain
ENST00000259053.6
11..709 (or 159771851.. 159798198)
159768628.. 159798208
NCBI Matured mRNA sequence 3932 NTPDownload 
m7G-5')ppp(5'-ACCCGCCGUCAUGCUCCGGGCCGCGCUGCCCGCGCUCCUGCUGCCGUUGCUGGGCCUCGCCGCUGCUGCCGUCGCGGACUGUCCUUCAUCUACUUGGAUUCAGUUCCAAGACAGUUGUUACAUUUUUCUCCAAGAAGCCAUCAAAGUAGAAAGCAUAGAGGAUGUCAGAAAUCAGUGUACUGACCAUGGAGCGGACAUGAUAAGCAUACAUAAUGAAGAAGAAAAUGCUUUUAUACUGGAUACUUUGAAAAAGCAAUGGAAAGGCCCAGAUGAUAUCCUACUAGGCAUGUUUUAUGACACAGAUGAUGCGAGUUUCAAGUGGUUUGAUAAUUCAAAUAUGACAUUUGAUAAGUGGACAGACCAAGAUGAUGAUGAGGAUUUAGUUGACACCUGUGCUUUUCUGCACAUCAAGACAGGUGAAUGGAAAAAAGGAAAUUGUGAAGUUUCUUCUGUGGAAGGAACACUAUGCAAAACAGCUAUCCCAUACAAAAGGAAAUAUUUAUCAGAUAACCACAUUUUAAUAUCAGCAUUGGUGAUUGCUAGCACGGUAAUUUUGACAGUUUUGGGAGCAAUCAUUUGGUUCCUGUACAAAAAACAUUCUGAUUCUCGUUUCACCACAGUUUUUUCAACCGCACCCCAAUCACCUUAUAAUGAAGACUGUGUUUUGGUAGUUGGAGAAGAAAAUGAAUAUCCUGUUCAAUUUGACUAAGUUUUUGGUAAUCUUGCACUAAGACAUCAACAAAAUGCCCUGGCAGAGAUAACUUGGGAAAGAUUUUAAUAUAAAACUUGACAUUGGAUAUUAGAGCUUUAAUGGUAUUCCUUAUUCCAGUAACAUUUUUAUGUACUCAUCUGCUGUGAAAAGUCUUUAGGUUCAUUAAAAAAACAGGUUUUAGAAAUGAUCUUAGAUCUAAUAUAGUGAUUUUAAGCAUCCCGUCAAAGGCAGAAUCUGUCACUUGAAUGAAGGAAAGCUUAAAGCCCAAGCAGAUAAAAAUAAAAGCCCAGCCUAUUUGUCUUGCCUGCUGUAUCUUCCCUAUUUAGUUGACCCACUUUAGUUUAUAUGUUUAUUAGUAAACAUGAAAUGGGGAAUAAGUGAUUUUAAGUACAUCCCAUACAUUUAAAUAUCUUUGAUAAUUGUUAUUUUUUUGGCAGAUAAUUCCUCUAGAAUGUGUAUCUUUUUAUGAUUUAGAUGAAGAAAAUUUUACAACUUUUAACACCCCACACCAAUUUUAGUUUCAUUACUUUUACACACACCAUUUUAUCACAAAUGACUCAAGUUUUAAUGAAUGUUUAUAAAUUAUUUGAAACAAAAUAUGAUCGCUGUGUCCAGGAUGGCAUAGAGAAAGCUGGCAAUUAGGUUAACACUUACAUAUUAUAGUGCCCCUUUAAGGAUUUCUCUCUUGCCACCAUACCUUUUGUACUUUCCCCUAUACAAGAUGUAUCUCAUUCUCCUCAAGCAUUUAUAAAUUUUUCCUUCAAUGACAUGAAAACUGUGCAAGCAAAAACCGAAGAAAAACACUUAAGUACAACUGUAGUGACAGUGAUCAAAGUUUUCAGUGCAUUUAUUGUACAUUUUAAGAAAAAGGUGAAAAUCAUUUGGGGAGUAAAAAAAUGAAAAAGCUGAAACGAGUAAUUUUCCUCACCAUCAAUAAACCAAAAACAGGAAAGAUAAAGAAUGUAUAAAUUUCACGUAAAUUAGUCACGUAUCACUUAUCAAUGGGGAUACGUUCUAAGAAAUGCAUAGUUAGGGAAUCUUGUGUGAAAAUCAGCUUGUAUUUACACAAACCCAGAUGGUAGAGCCUAUUUUGUCCCAAACCUACACAGCAUGUUACUGUGCUGAAUACUGCAGACAAUUGUAACACAAUAUUUGUGUAUCUAAAUAUAGAAAAGGUACAGUAAAAAUAUGGUCUACUAAGGAAACACUGUUCUAUAUGUGGUCCAUUACUGACUGAAGUAUACUGUCUAGAAGUCUGAGGCUCAAAGAAAAGUAAUCCCUCUUCUGAAUCCACACCCCAUCAAUUAUCUUACUUUCUUCUGGGGAGAUAGAUAGAUAUACUAUCUCACUAGCUUGACUAAUGGCAACAAAGUUCCAGCUUGUGUAGUCUCUUUUUAUUGACCACAUGAAUCGAAAACACUCAUCACAAUUAAUGGCACUAUCAUUAAUGAGACAUGAGUAACUAAAAAGUGAUAGAAAACUAUUAACAGUGCGGCUACAUGGUACUGAAAAUGCAGGCAUUACACCAGCUGUUACACAAGCACAAGCAUGCUCUGUAAGAGCUUUACAUUUCUGAGAUUUUGUAUAGUGAUUGAGAUGUCUAUUUUAUUAUUGAUAGACUAUUACUAAUGUCAAUAUUGAACACUACCCUGGAAUUCCUGCCUGGUUUUCCUACCCAAAUUGUACCACUCCUUGAAGAACUACAGGCACAGUAAAAAAAAUAUGGCGUAUUAUGUGAACUAAAAGAGUUCUAAAGGAGUUCUUAAAGGAGUGGUAGAAUUUGGGUAGGAAAGUGAUUAAGUCCAACUUAAAACCAACAGUCUCAAACGUCUACAACUACAAUGUCCAAUGAGCCACUAGCCACAUGAGGCUAUUUAAGUAAAUUUAGUUUAAAAUCCAGUUUUCGAAUUACAUUAGCCACAUUGUCAAGUGUUCAAAUCACAGGUGGUUAGUGGCUACUGUACUGGGCAACAUACAUUAUAGAACAUUUUCAUUAUAGGAAGUUUUAUUGGGCAGUGCUGCUCUUAAAUCCUACCUUCCACUCAACUCCCAUACAACUUUCUUUUGUACAUUUUGAUACUUUCUACCUAAUGGCAGCUCUUCCAAAAUAGCUGCUUUAAACUCUGAUUUAAUUUUCAAUAUUUGGUUUCAUUUUUCAACAGGCCAAGAGGCCUCUGGUAAUGAAGUGCUAUAUAUAUAUAUAUGAUGGAGUCUCACUGUGCUGCCCAGGCUACAGUGCAGUGGCUCGAUCUUGGCUCUCUCCAAUCUCCGCCUUGCAGGUUUUCAAGCAAUUCUCCUGCCUCAGCCUCCUUAGUAGCUGGGACCACAGACAUCUGUCACCACACCCAGCUAACUUUUUGUAUUUUUGGUAGAGACGGGGUUUCGCCAUAUUGACUGGGCUGGUCUCAAACUCCUGACCUCAAGUGAUCCACCCACCUUGGUCUCCCAAAGUGCUGGGAUUACAUGCGUGAGCCACCACACUUGGCCUACAUUUUUUCUUUAUAUACCAGAACAUCUAUAACAGGCACCUUAUCUACUCAUUAGUGAAGAGAUAAUUGGAUUACACAGGCAGGCUUGUUUACUACAUCCAGAAUGUAGAAACUGCUUUCUUCAACAUCUUGGUUCUAGCUAGUAAUAACAAUAUAAUUCUUUGGCAGAUAUUCAGAAUAACAUUUUAAACUACAUUUUCUUAGAAAAUUGCAUUCUUGUAGUGAGCAGUGUAUGGUCUCUUUUGUUCAGAAUUUAAAACUGAUAACCAAUGAAAGCCUUUUCUCUUAUUCCUCUACCGUCAUUUACAUGAUAAUCUGAAGCUAAUAUGACAAUAUUUAAAUACUAAGUGGUACUAGGGAACUACAAGAAUACUGUAAAGCUUAAGCCAUUGUUAUCACUGUCAUUUAGCAUUUAAUAACAAAACUAUACAGAAUUAUGUGCAUACCAAUGAAUGUUUUGUACCAUCUAGUUAAAUUUUUUAAAUAAAGUUUUAUGGGUUAAGCAGAAGACAACUGUCAUACUGAAUUUUAUUAAAAGUAUAUAUACUUCAAAUUCAAAGCAUCCCUUAGGACCCACAGAAUAUAUUAAAACUACCACCCUUAAAUUUUAUAUUUUUGCUUUAAGACAGACAAUGCAAAGGUAACUGGCAAGAGGUGAGCAAAUGUUUUAGAACAUUUAUAUUAUUGCUUAAAAUGAGAUUUGAAAUUGUAAUAAAAUUCUUGGUUAUGAA-3'- Poly-A tail
  • Coding region
NCBI Matured mRNA sequence viewer
;
More about the NCBI sViewer.
DNA
DNA (Gene ID: 9936)
CD302
CD302 molecule
NC_000002.12
2  159771851.. 159798198
159771851.. 159798198
strand -
CCDS33308.1
MGI:1913455
ClinVar, dbVar
ENSG00000241399
DCL-1, KIAA0022, BIMLEC, CLEC13A
uc002uba.4
INSDC: AY314007
30843
612246
OTTHUMG00000154080
ENA, DDBJ, Monarch
CD302
NCBI CDS Gene viewer
More about the NCBI sViewer.
NCBI CDS gene sequence (699 bp)
5'-ATGCTCCGGGCCGCGCTGCCCGCGCTCCTGCTGCCGTTGCTGGGCCTCGCCGCTGCTGCCGTCGCGGACTGTCCTTCATCTACTTGGATTCAGTTCCAAGACAGTTGTTACATTTTTCTCCAAGAAGCCATCAAAGTAGAAAGCATAGAGGATGTCAGAAATCAGTGTACTGACCATGGAGCGGACATGATAAGCATACATAATGAAGAAGAAAATGCTTTTATACTGGATACTTTGAAAAAGCAATGGAAAGGCCCAGATGATATCCTACTAGGCATGTTTTATGACACAGATGATGCGAGTTTCAAGTGGTTTGATAATTCAAATATGACATTTGATAAGTGGACAGACCAAGATGATGATGAGGATTTAGTTGACACCTGTGCTTTTCTGCACATCAAGACAGGTGAATGGAAAAAAGGAAATTGTGAAGTTTCTTCTGTGGAAGGAACACTATGCAAAACAGCTATCCCATACAAAAGGAAATATTTATCAGATAACCACATTTTAATATCAGCATTGGTGATTGCTAGCACGGTAATTTTGACAGTTTTGGGAGCAATCATTTGGTTCCTGTACAAAAAACATTCTGATTCTCGTTTCACCACAGTTTTTTCAACCGCACCCCAATCACCTTATAATGAAGACTGTGTTTTGGTAGTTGGAGAAGAAAATGAATATCCTGTTCAATTTGACTAA-3'
NCBI CDS gene sequence with introns (location: 159771851.. 159798198) (26348 bp)Download
NCBI Gene Viewer (CDS + introns)
NCBI CDS gene sequence with introns, 5'UTR and 3'UTR (location: 159768628.. 159798208) (29581 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions)
NCBI gene sequence (location: [159768628.. 159798208 + 1000]) (30581 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions + 1000 dNTP to potentially reach the promotor)
Cite How to cite