HumanLectome - Human Lectin Entry

NCBI Summary

This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration. [provided by RefSeq, Jul 2011].

Protein name

Tenascin

Synonym(s)

Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (Tenascin-C) (TN-C)

HGNC gene name

TNC

HGNC name

tenascin C

Protein_CD_name

Undefined

Lectin confidence

Very low evidence

UniLectin class

Ficolin-like

Known lectin group

Undefined

Lectin fold

a/b mixed with b-sheet / Fibrinogen C-ter like

Glycan specificity

Uncharacterised

RefSeq accession

Gene ID

UniProt accession

Ensembl protein ID

UniRef cluster ID

LectomeXplore score

0.579

Reference

Undefined

Other links

neXtProt, PFAM, InterPro

Protein sequence and protein families (fasta) (2201 amino acids) Download

MGAMTQLLAGVFLAFLALATEGGVLKKVIRHKRQSGVNATLPEENQPVVFNHVYNIKLPVGSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRINIPRRACGCAAAPDVKELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEGRRKRA

Mol* PDB structure viewerUniLectin3D

Select a PDB entry:

Structural models

AlphaFold v2: AF-P24821-F1 Download

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Expression

Human Protein Atlas

GeneCards

mRNA expression in normal human tissues for TNC Gene

ProteomicsDB

References

NCBI References (10 PubMed Identifiers)

Functions of Matricellular Proteins in Dental Tissues and Their Emerging Roles in Orofacial Tissue Development, Maintenance, and Disease. [34205668]

Tenascin-C immobilizes infiltrating T lymphocytes through CXCL12 promoting breast cancer progression. [33988305]

An integrated approach for identification of a panel of candidate genes arbitrated for invasion and metastasis in oral squamous cell carcinoma. [33739025]

Extracellular matrix changes in corneal opacification vary depending on etiology. [33633437]

Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging. [33217999]

Structure and chromosomal localization of the human gene for a brain form of prostaglandin D2 synthase. [1385416]

Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein. [1279805]

Structure of the human hexabrachion (tenascin) gene. [1719530]

The complete cDNA sequence of human hexabrachion (Tenascin). A multidomain protein containing unique epidermal growth factor repeats. [1704365]

Human tenascin: primary structure, pre-mRNA splicing patterns and localization of the epitopes recognized by two monoclonal antibodies. [1707164]

UniProt Main References (13 PubMed Identifiers)

Human tenascin gene. Structure of the 5'-region, identification, and characterization of the transcription regulatory sequences. [7531707]

DNA sequence and analysis of human chromosome 9. [15164053]

Analysis of aggrecan and tenascin gene expression in mouse skeletal tissues by northern and in situ hybridization using species specific cDNA probes. [7524681]

An alternatively spliced region of the human hexabrachion contains a repeat of potential N-glycosylation sites. [2466295]

Binding of the NG2 proteoglycan to type VI collagen and other extracellular matrix molecules. [8824254]

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. [16335952]

Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry. [18780401]

Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. [19159218]

Tenascin-W is a specific marker of glioma-associated blood vessels and stimulates angiogenesis in vitro. [19884327]

Initial characterization of the human central proteome. [21269460]

All isoforms of this gene containing a lectin domain

XP_005252032.1, XP_006717164.1, XP_005252031.1, XP_011516930.1, XP_011516931.1, XP_005252030.1, XP_011516928.1, XP_016870170.1, XP_011516927.1, XP_006717161.1, XP_005252029.1, XP_006717160.1, XP_006717159.1, XP_016870168.1, NP_002151.2, XP_016870167.1, XP_024303298.1, XP_016870169.1

RNA

RNA (Transcript ID: NM_002160.4)

RNA RefSeq ID

NM_002160.4

RNA name

tenascin C

Isoforms

All isoforms of TNC containing a lectin domain

RNA Ensembl ID

ENST00000350763.9

Coding region

313..6918 (or 115021157.. 115091018)

mRNA location

115019575.. 115118157

NCBI Matured mRNA sequence 8500 NTP Download

m⁷G-5')ppp(5'-GGCCACAGCCUGCCUACUGUCACCCGCCUCUCCCGCGCGCAGAUACACGCCCCCGCCUCCGUGGGCACAAAGGCAGCGCUGCUGGGGAACUCGGGGGAACGCGCACGUGGGAACCGCCGCAGCUCCACACUCCAGGUACUUCUUCCAAGGACCUAGGUCUCUCGCCCAUCGGAAAGAAAAUAAUUCUUUCAAGAAGAUCAGGGACAACUGAUUUGAAGUCUACUCUGUGCUUCUAAAUCCCCAAUUCUGCUGAAAGUGAGAUACCCUAGAGCCCUAGAGCCCCAGCAGCACCCAGCCAAACCCACCUCCACCAUGGGGGCCAUGACUCAGCUGUUGGCAGGUGUCUUUCUUGCUUUCCUUGCCCUCGCUACCGAAGGUGGGGUCCUCAAGAAAGUCAUCCGGCACAAGCGACAGAGUGGGGUGAACGCCACCCUGCCAGAAGAGAACCAGCCAGUGGUGUUUAACCACGUUUACAACAUCAAGCUGCCAGUGGGAUCCCAGUGUUCGGUGGAUCUGGAGUCAGCCAGUGGGGAGAAAGACCUGGCACCGCCUUCAGAGCCCAGCGAAAGCUUUCAGGAGCACACAGUGGAUGGGGAAAACCAGAUUGUCUUCACACAUCGCAUCAACAUCCCCCGCCGGGCCUGUGGCUGUGCCGCAGCCCCUGAUGUUAAGGAGCUGCUGAGCAGACUGGAGGAGCUGGAGAACCUGGUGUCUUCCCUGAGGGAGCAAUGUACUGCAGGAGCAGGCUGCUGUCUCCAGCCUGCCACAGGCCGCUUGGACACCAGGCCCUUCUGUAGCGGUCGGGGCAACUUCAGCACUGAAGGAUGUGGCUGUGUCUGCGAACCUGGCUGGAAAGGCCCCAACUGCUCUGAGCCCGAAUGUCCAGGCAACUGUCACCUUCGAGGCCGGUGCAUUGAUGGGCAGUGCAUCUGUGACGACGGCUUCACGGGCGAGGACUGCAGCCAGCUGGCUUGCCCCAGCGACUGCAAUGACCAGGGCAAGUGCGUAAAUGGAGUCUGCAUCUGUUUCGAAGGCUACGCCGGGGCUGACUGCAGCCGUGAAAUCUGCCCAGUGCCCUGCAGUGAGGAGCACGGCACAUGUGUAGAUGGCUUGUGUGUGUGCCACGAUGGCUUUGCAGGCGAUGACUGCAACAAGCCUCUGUGUCUCAACAAUUGCUACAACCGUGGACGAUGCGUGGAGAAUGAGUGCGUGUGUGAUGAGGGUUUCACGGGCGAAGACUGCAGUGAGCUCAUCUGCCCCAAUGACUGCUUCGACCGGGGCCGCUGCAUCAAUGGCACCUGCUACUGCGAAGAAGGCUUCACAGGUGAAGACUGCGGGAAACCCACCUGCCCACAUGCCUGCCACACCCAGGGCCGGUGUGAGGAGGGGCAGUGUGUAUGUGAUGAGGGCUUUGCCGGUGUGGACUGCAGCGAGAAGAGGUGUCCUGCUGACUGUCACAAUCGUGGCCGCUGUGUAGACGGGCGGUGUGAGUGUGAUGAUGGUUUCACUGGAGCUGACUGUGGGGAGCUCAAGUGUCCCAAUGGCUGCAGUGGCCAUGGCCGCUGUGUCAAUGGGCAGUGUGUGUGUGAUGAGGGCUAUACUGGGGAGGACUGCAGCCAGCUACGGUGCCCCAAUGACUGUCACAGUCGGGGCCGCUGUGUCGAGGGCAAAUGUGUAUGUGAGCAAGGCUUCAAGGGCUAUGACUGCAGUGACAUGAGCUGCCCUAAUGACUGUCACCAGCACGGCCGCUGUGUGAAUGGCAUGUGUGUUUGUGAUGACGGCUACACAGGGGAAGACUGCCGGGAUCGCCAAUGCCCCAGGGACUGCAGCAACAGGGGCCUCUGUGUGGACGGACAGUGCGUCUGUGAGGACGGCUUCACCGGCCCUGACUGUGCAGAACUCUCCUGUCCAAAUGACUGCCAUGGCCAGGGUCGCUGUGUGAAUGGGCAGUGCGUGUGCCAUGAAGGAUUUAUGGGCAAAGACUGCAAGGAGCAAAGAUGUCCCAGUGACUGUCAUGGCCAGGGCCGCUGCGUGGACGGCCAGUGCAUCUGCCACGAGGGCUUCACAGGCCUGGACUGUGGCCAGCACUCCUGCCCCAGUGACUGCAACAACUUAGGACAAUGCGUCUCGGGCCGCUGCAUCUGCAACGAGGGCUACAGCGGAGAAGACUGCUCAGAGGUGUCUCCUCCCAAAGACCUCGUUGUGACAGAAGUGACGGAAGAGACGGUCAACCUGGCCUGGGACAAUGAGAUGCGGGUCACAGAGUACCUUGUCGUGUACACGCCCACCCACGAGGGUGGUCUGGAAAUGCAGUUCCGUGUGCCUGGGGACCAGACGUCCACCAUCAUCCAGGAGCUGGAGCCUGGUGUGGAGUACUUUAUCCGUGUAUUUGCCAUCCUGGAGAACAAGAAGAGCAUUCCUGUCAGCGCCAGGGUGGCCACGUACUUACCUGCACCUGAAGGCCUGAAAUUCAAGUCCAUCAAGGAGACAUCUGUGGAAGUGGAGUGGGAUCCUCUAGACAUUGCUUUUGAAACCUGGGAGAUCAUCUUCCGGAAUAUGAAUAAAGAAGAUGAGGGAGAGAUCACCAAAAGCCUGAGGAGGCCAGAGACCUCUUACCGGCAAACUGGUCUAGCUCCUGGGCAAGAGUAUGAGAUAUCUCUGCACAUAGUGAAAAACAAUACCCGGGGCCCUGGCCUGAAGAGGGUGACCACCACACGCUUGGAUGCCCCCAGCCAGAUCGAGGUGAAAGAUGUCACAGACACCACUGCCUUGAUCACCUGGUUCAAGCCCCUGGCUGAGAUCGAUGGCAUUGAGCUGACCUACGGCAUCAAAGACGUGCCAGGAGACCGUACCACCAUCGAUCUCACAGAGGACGAGAACCAGUACUCCAUCGGGAACCUGAAGCCUGACACUGAGUACGAGGUGUCCCUCAUCUCCCGCAGAGGUGACAUGUCAAGCAACCCAGCCAAAGAGACCUUCACAACAGGCCUCGAUGCUCCCAGGAAUCUUCGACGUGUUUCCCAGACAGAUAACAGCAUCACCCUGGAAUGGAGGAAUGGCAAGGCAGCUAUUGACAGUUACAGAAUUAAGUAUGCCCCCAUCUCUGGAGGGGACCACGCUGAGGUUGAUGUUCCAAAGAGCCAACAAGCCACAACCAAAACCACACUCACAGGUCUGAGGCCGGGAACUGAAUAUGGGAUUGGAGUUUCUGCUGUGAAGGAAGACAAGGAGAGCAAUCCAGCGACCAUCAACGCAGCCACAGAGUUGGACACGCCCAAGGACCUUCAGGUUUCUGAAACUGCAGAGACCAGCCUGACCCUGCUCUGGAAGACACCGUUGGCCAAAUUUGACCGCUACCGCCUCAAUUACAGUCUCCCCACAGGCCAGUGGGUGGGAGUGCAGCUUCCAAGAAACACCACUUCCUAUGUCCUGAGAGGCCUGGAACCAGGACAGGAGUACAAUGUCCUCCUGACAGCCGAGAAAGGCAGACACAAGAGCAAGCCCGCACGUGUGAAGGCAUCCACUGAACAAGCCCCUGAGCUGGAAAACCUCACCGUGACUGAGGUUGGCUGGGAUGGCCUCAGACUCAACUGGACCGCAGCUGACCAGGCCUAUGAGCACUUUAUCAUUCAGGUGCAGGAGGCCAACAAGGUGGAGGCAGCUCGGAACCUCACCGUGCCUGGCAGCCUUCGGGCUGUGGACAUACCGGGCCUCAAGGCUGCUACGCCUUAUACAGUCUCCAUCUAUGGGGUGAUCCAGGGCUAUAGAACACCAGUGCUCUCUGCUGAGGCCUCCACAGGGGAAACUCCCAAUUUGGGAGAGGUCGUGGUGGCCGAGGUGGGCUGGGAUGCCCUCAAACUCAACUGGACUGCUCCAGAAGGGGCCUAUGAGUACUUUUUCAUUCAGGUGCAGGAGGCUGACACAGUAGAGGCAGCCCAGAACCUCACCGUCCCAGGAGGACUGAGGUCCACAGACCUGCCUGGGCUCAAAGCAGCCACUCAUUAUACCAUCACCAUCCGCGGGGUCACUCAGGACUUCAGCACAACCCCUCUCUCUGUUGAAGUCUUGACAGAGGAGGUUCCAGAUAUGGGAAACCUCACAGUGACCGAGGUUAGCUGGGAUGCUCUCAGACUGAACUGGACCACGCCAGAUGGAACCUAUGACCAGUUUACUAUUCAGGUCCAGGAGGCUGACCAGGUGGAAGAGGCUCACAAUCUCACGGUUCCUGGCAGCCUGCGUUCCAUGGAAAUCCCAGGCCUCAGGGCUGGCACUCCUUACACAGUCACCCUGCACGGCGAGGUCAGGGGCCACAGCACUCGACCCCUUGCUGUAGAGGUCGUCACAGAGGAUCUCCCACAGCUGGGAGAUUUAGCCGUGUCUGAGGUUGGCUGGGAUGGCCUCAGACUCAACUGGACCGCAGCUGACAAUGCCUAUGAGCACUUUGUCAUUCAGGUGCAGGAGGUCAACAAAGUGGAGGCAGCCCAGAACCUCACGUUGCCUGGCAGCCUCAGGGCUGUGGACAUCCCGGGCCUCGAGGCUGCCACGCCUUAUAGAGUCUCCAUCUAUGGGGUGAUCCGGGGCUAUAGAACACCAGUACUCUCUGCUGAGGCCUCCACAGCCAAAGAACCUGAAAUUGGAAACUUAAAUGUUUCUGACAUAACUCCCGAGAGCUUCAAUCUCUCCUGGAUGGCUACCGAUGGGAUCUUCGAGACCUUUACCAUUGAAAUUAUUGAUUCCAAUAGGUUGCUGGAGACUGUGGAAUAUAAUAUCUCUGGUGCUGAACGAACUGCCCAUAUCUCAGGGCUACCCCCUAGUACUGAUUUUAUUGUCUACCUCUCUGGACUUGCUCCCAGCAUCCGGACCAAAACCAUCAGUGCCACAGCCACGACAGAGGCCCUGCCCCUUCUGGAAAACCUAACCAUUUCCGACAUUAAUCCCUACGGGUUCACAGUUUCCUGGAUGGCAUCGGAGAAUGCCUUUGACAGCUUUCUAGUAACGGUGGUGGAUUCUGGGAAGCUGCUGGACCCCCAGGAAUUCACACUUUCAGGAACCCAGAGGAAGCUGGAGCUUAGAGGCCUCAUAACUGGCAUUGGCUAUGAGGUUAUGGUCUCUGGCUUCACCCAAGGGCAUCAAACCAAGCCCUUGAGGGCUGAGAUUGUUACAGAAGCCGAACCGGAAGUUGACAACCUUCUGGUUUCAGAUGCCACCCCAGACGGUUUCCGUCUGUCCUGGACAGCUGAUGAAGGGGUCUUCGACAAUUUUGUUCUCAAAAUCAGAGAUACCAAAAAGCAGUCUGAGCCACUGGAAAUAACCCUACUUGCCCCCGAACGUACCAGGGACAUAACAGGUCUCAGAGAGGCUACUGAAUACGAAAUUGAACUCUAUGGAAUAAGCAAAGGAAGGCGAUCCCAGACAGUCAGUGCUAUAGCAACAACAGCCAUGGGCUCCCCAAAGGAAGUCAUUUUCUCAGACAUCACUGAAAAUUCGGCUACUGUCAGCUGGAGGGCACCCACAGCCCAAGUGGAGAGCUUCCGGAUUACCUAUGUGCCCAUUACAGGAGGUACACCCUCCAUGGUAACUGUGGACGGAACCAAGACUCAGACCAGGCUGGUGAAACUCAUACCUGGCGUGGAGUACCUUGUCAGCAUCAUCGCCAUGAAGGGCUUUGAGGAAAGUGAACCUGUCUCAGGGUCAUUCACCACAGCUCUGGAUGGCCCAUCUGGCCUGGUGACAGCCAACAUCACUGACUCAGAAGCCUUGGCCAGGUGGCAGCCAGCCAUUGCCACUGUGGACAGUUAUGUCAUCUCCUACACAGGCGAGAAAGUGCCAGAAAUUACACGCACGGUGUCCGGGAACACAGUGGAGUAUGCUCUGACCGACCUCGAGCCUGCCACGGAAUACACACUGAGAAUCUUUGCAGAGAAAGGGCCCCAGAAGAGCUCAACCAUCACUGCCAAGUUCACAACAGACCUCGAUUCUCCAAGAGACUUGACUGCUACUGAGGUUCAGUCGGAAACUGCCCUCCUUACCUGGCGACCCCCCCGGGCAUCAGUCACCGGUUACCUGCUGGUCUAUGAAUCAGUGGAUGGCACAGUCAAGGAAGUCAUUGUGGGUCCAGAUACCACCUCCUACAGCCUGGCAGACCUGAGCCCAUCCACCCACUACACAGCCAAGAUCCAGGCACUCAAUGGGCCCCUGAGGAGCAAUAUGAUCCAGACCAUCUUCACCACAAUUGGACUCCUGUACCCCUUCCCCAAGGACUGCUCCCAAGCAAUGCUGAAUGGAGACACGACCUCUGGCCUCUACACCAUUUAUCUGAAUGGUGAUAAGGCUGAGGCGCUGGAAGUCUUCUGUGACAUGACCUCUGAUGGGGGUGGAUGGAUUGUGUUCCUGAGACGCAAAAACGGACGCGAGAACUUCUACCAAAACUGGAAGGCAUAUGCUGCUGGAUUUGGGGACCGCAGAGAAGAAUUCUGGCUUGGGCUGGACAACCUGAACAAAAUCACAGCCCAGGGGCAGUACGAGCUCCGGGUGGACCUGCGGGACCAUGGGGAGACAGCCUUUGCUGUCUAUGACAAGUUCAGCGUGGGAGAUGCCAAGACUCGCUACAAGCUGAAGGUGGAGGGGUACAGUGGGACAGCAGGUGACUCCAUGGCCUACCACAAUGGCAGAUCCUUCUCCACCUUUGACAAGGACACAGAUUCAGCCAUCACCAACUGUGCUCUGUCCUACAAAGGGGCUUUCUGGUACAGGAACUGUCACCGUGUCAACCUGAUGGGGAGAUAUGGGGACAAUAACCACAGUCAGGGCGUUAACUGGUUCCACUGGAAGGGCCACGAACACUCAAUCCAGUUUGCUGAGAUGAAGCUGAGACCAAGCAACUUCAGAAAUCUUGAAGGCAGGCGCAAACGGGCAUAAAUUCCAGGGACCACUGGGUGAGAGAGGAAUAAGGCCCAGAGCGAGGAAAGGAUUUUACCAAAGCAUCAAUACAACCAGCCCAACCAUCGGUCCACACCUGGGCAUUUGGUGAGAGUCAAAGCUGACCAUGGAUCCCUGGGGCCAACGGCAACAGCAUGGGCCUCACCUCCUCUGUGAUUUCUUUCUUUGCACCAAAGACAUCAGUCUCCAACAUGUUUCUGUUUUGUUGUUUGAUUCAGCAAAAAUCUCCCAGUGACAACAUCGCAAUAGUUUUUUACUUCUCUUAGGUGGCUCUGGGAAUGGGAGAGGGGUAGGAUGUACAGGGGUAGUUUGUUUUAGAACCAGCCGUAUUUUACAUGAAGCUGUAUAAUUAAUUGUCAUUAUUUUUGUUAGCAAAGAUUAAAUGUGUCAUUGGAAGCCAUCCCUUUUUUUACAUUUCAUACAACAGAAACCAGAAAAGCAAUACUGUUUCCAUUUUAAGGAUAUGAUUAAUAUUAUUAAUAUAAUAAUGAUGAUGAUGAUGAUGAAAACUAAGGAUUUUUCAAGAGAUCUUUCUUUCCAAAACAUUUCUGGACAGUACCUGAUUGUAUUUUUUUUUUAAAUAAAAGCACAAGUACUUUUGAGUUUGUUAUUUUGCUUUGAAUUGUUGAGUCUGAAUUUCACCAAAGCCAAUCAUUUGAACAAAGCGGGGAAUGUUGGGAUAGGAAAGGUAAGUAGGGAUAGUGGUCAAGUGGGAGGGGUGGAAAGGAGACUAAAGACUGGGAGAGAGGGAAGCACUUUUUUUAAAUAAAGUUGAACACACUUGGGAAAAGCUUACAGGCCAGGCCUGUAAUCCCAACACUUUGGGAGGCCAAGGUGGGAGGAUAGCUUAACCCCAGGAGUUUGAGACCAGCCUGAGCAACAUAGUGAGAACUUGUCUCUACAGAAAAAAAAAAAAAAAAAAAUUUAAUUAGGCAAGCGUGGUAGUGCGCACCUGUCGUCCCAGCUACUCAGGAGGCUGAGGUAGGAAAAUCACUGGAGCCCAGGAGUUAGAGGUUACAGUGAGCUAUGAUCACACUACUGCACUCCAGCCUGGGCAACAGAGGGAGACCCUGUCUCUAAAUAAAAAAAGAAAAGAAAAAAAAAGCUUACAACUUGAGAUUCAGCAUCUUGCUCAGUAUUUCCAAGACUAAUAGAUUAUGGUUUAAAAGAUGCUUUUAUACUCAUUUUCUAAUGCAACUCCUAGAAACUCUAUGAUAUAGUUGAGGUAAGUAUUGUUACCACACAUGGGCUAAGAUCCCCAGAGGCAGACUGCCUGAGUUCAAUUCUUGGCUCCACCAUUCCCAAGUUCCCUAACCUCUCUAUGCCUCAGUUUCCUCUUCUGUAAAGUAGGGACACUCAUACUUCUCAUUUCAGAACAUUUUUGUGAAGAAUAAAUUAUGUUAUCCAUUUGAGGCCCUUAGAAUGGUACCCGGUGUAUAUUAAGUGCUAGUACAUGUUAGCUAUCAUCAUUAUCACUUUAUAUGAGAUGGACUGGGGUUCAUAGAAACCCAAUGACUUGAUUGUGGCUACUACUCAAUAAAUAAUAGAAUUUGGAUUUAAA-3'- Poly-A tail

Coding region

NCBI Matured mRNA sequence viewer

;

More about the NCBI sViewer.

DNA

DNA (Gene ID: 3371)

HGNC Gene symbol

TNC

HGNC Gene name

tenascin C

Chr. RefSeq ID

NC_000009.12

Chromosome N°

9 115021157.. 115091018

CDS location

115021157.. 115091018

DNA strand

strand -

CCDS ID

CCDS6811.1

Mouse ortholog gene

MGI:101922

Gene Variant

ClinVar, dbVar

DNA Ensembl ID

ENSG00000041982

HGNC other symbol

TN, MGC167029

UCSC ID

uc004bjj.6

GeneBank

INSDC:

GeneCards

5318

MIM

187380

VEGA ID

OTTHUMG00000021010

Other links

ENA, DDBJ, Monarch

NCBI CDS Gene viewer

More about the NCBI sViewer.

NCBI CDS gene sequence (6606 bp)

5'-ATGGGGGCCATGACTCAGCTGTTGGCAGGTGTCTTTCTTGCTTTCCTTGCCCTCGCTACCGAAGGTGGGGTCCTCAAGAAAGTCATCCGGCACAAGCGACAGAGTGGGGTGAACGCCACCCTGCCAGAAGAGAACCAGCCAGTGGTGTTTAACCACGTTTACAACATCAAGCTGCCAGTGGGATCCCAGTGTTCGGTGGATCTGGAGTCAGCCAGTGGGGAGAAAGACCTGGCACCGCCTTCAGAGCCCAGCGAAAGCTTTCAGGAGCACACAGTGGATGGGGAAAACCAGATTGTCTTCACACATCGCATCAACATCCCCCGCCGGGCCTGTGGCTGTGCCGCAGCCCCTGATGTTAAGGAGCTGCTGAGCAGACTGGAGGAGCTGGAGAACCTGGTGTCTTCCCTGAGGGAGCAATGTACTGCAGGAGCAGGCTGCTGTCTCCAGCCTGCCACAGGCCGCTTGGACACCAGGCCCTTCTGTAGCGGTCGGGGCAACTTCAGCACTGAAGGATGTGGCTGTGTCTGCGAACCTGGCTGGAAAGGCCCCAACTGCTCTGAGCCCGAATGTCCAGGCAACTGTCACCTTCGAGGCCGGTGCATTGATGGGCAGTGCATCTGTGACGACGGCTTCACGGGCGAGGACTGCAGCCAGCTGGCTTGCCCCAGCGACTGCAATGACCAGGGCAAGTGCGTAAATGGAGTCTGCATCTGTTTCGAAGGCTACGCCGGGGCTGACTGCAGCCGTGAAATCTGCCCAGTGCCCTGCAGTGAGGAGCACGGCACATGTGTAGATGGCTTGTGTGTGTGCCACGATGGCTTTGCAGGCGATGACTGCAACAAGCCTCTGTGTCTCAACAATTGCTACAACCGTGGACGATGCGTGGAGAATGAGTGCGTGTGTGATGAGGGTTTCACGGGCGAAGACTGCAGTGAGCTCATCTGCCCCAATGACTGCTTCGACCGGGGCCGCTGCATCAATGGCACCTGCTACTGCGAAGAAGGCTTCACAGGTGAAGACTGCGGGAAACCCACCTGCCCACATGCCTGCCACACCCAGGGCCGGTGTGAGGAGGGGCAGTGTGTATGTGATGAGGGCTTTGCCGGTGTGGACTGCAGCGAGAAGAGGTGTCCTGCTGACTGTCACAATCGTGGCCGCTGTGTAGACGGGCGGTGTGAGTGTGATGATGGTTTCACTGGAGCTGACTGTGGGGAGCTCAAGTGTCCCAATGGCTGCAGTGGCCATGGCCGCTGTGTCAATGGGCAGTGTGTGTGTGATGAGGGCTATACTGGGGAGGACTGCAGCCAGCTACGGTGCCCCAATGACTGTCACAGTCGGGGCCGCTGTGTCGAGGGCAAATGTGTATGTGAGCAAGGCTTCAAGGGCTATGACTGCAGTGACATGAGCTGCCCTAATGACTGTCACCAGCACGGCCGCTGTGTGAATGGCATGTGTGTTTGTGATGACGGCTACACAGGGGAAGACTGCCGGGATCGCCAATGCCCCAGGGACTGCAGCAACAGGGGCCTCTGTGTGGACGGACAGTGCGTCTGTGAGGACGGCTTCACCGGCCCTGACTGTGCAGAACTCTCCTGTCCAAATGACTGCCATGGCCAGGGTCGCTGTGTGAATGGGCAGTGCGTGTGCCATGAAGGATTTATGGGCAAAGACTGCAAGGAGCAAAGATGTCCCAGTGACTGTCATGGCCAGGGCCGCTGCGTGGACGGCCAGTGCATCTGCCACGAGGGCTTCACAGGCCTGGACTGTGGCCAGCACTCCTGCCCCAGTGACTGCAACAACTTAGGACAATGCGTCTCGGGCCGCTGCATCTGCAACGAGGGCTACAGCGGAGAAGACTGCTCAGAGGTGTCTCCTCCCAAAGACCTCGTTGTGACAGAAGTGACGGAAGAGACGGTCAACCTGGCCTGGGACAATGAGATGCGGGTCACAGAGTACCTTGTCGTGTACACGCCCACCCACGAGGGTGGTCTGGAAATGCAGTTCCGTGTGCCTGGGGACCAGACGTCCACCATCATCCAGGAGCTGGAGCCTGGTGTGGAGTACTTTATCCGTGTATTTGCCATCCTGGAGAACAAGAAGAGCATTCCTGTCAGCGCCAGGGTGGCCACGTACTTACCTGCACCTGAAGGCCTGAAATTCAAGTCCATCAAGGAGACATCTGTGGAAGTGGAGTGGGATCCTCTAGACATTGCTTTTGAAACCTGGGAGATCATCTTCCGGAATATGAATAAAGAAGATGAGGGAGAGATCACCAAAAGCCTGAGGAGGCCAGAGACCTCTTACCGGCAAACTGGTCTAGCTCCTGGGCAAGAGTATGAGATATCTCTGCACATAGTGAAAAACAATACCCGGGGCCCTGGCCTGAAGAGGGTGACCACCACACGCTTGGATGCCCCCAGCCAGATCGAGGTGAAAGATGTCACAGACACCACTGCCTTGATCACCTGGTTCAAGCCCCTGGCTGAGATCGATGGCATTGAGCTGACCTACGGCATCAAAGACGTGCCAGGAGACCGTACCACCATCGATCTCACAGAGGACGAGAACCAGTACTCCATCGGGAACCTGAAGCCTGACACTGAGTACGAGGTGTCCCTCATCTCCCGCAGAGGTGACATGTCAAGCAACCCAGCCAAAGAGACCTTCACAACAGGCCTCGATGCTCCCAGGAATCTTCGACGTGTTTCCCAGACAGATAACAGCATCACCCTGGAATGGAGGAATGGCAAGGCAGCTATTGACAGTTACAGAATTAAGTATGCCCCCATCTCTGGAGGGGACCACGCTGAGGTTGATGTTCCAAAGAGCCAACAAGCCACAACCAAAACCACACTCACAGGTCTGAGGCCGGGAACTGAATATGGGATTGGAGTTTCTGCTGTGAAGGAAGACAAGGAGAGCAATCCAGCGACCATCAACGCAGCCACAGAGTTGGACACGCCCAAGGACCTTCAGGTTTCTGAAACTGCAGAGACCAGCCTGACCCTGCTCTGGAAGACACCGTTGGCCAAATTTGACCGCTACCGCCTCAATTACAGTCTCCCCACAGGCCAGTGGGTGGGAGTGCAGCTTCCAAGAAACACCACTTCCTATGTCCTGAGAGGCCTGGAACCAGGACAGGAGTACAATGTCCTCCTGACAGCCGAGAAAGGCAGACACAAGAGCAAGCCCGCACGTGTGAAGGCATCCACTGAACAAGCCCCTGAGCTGGAAAACCTCACCGTGACTGAGGTTGGCTGGGATGGCCTCAGACTCAACTGGACCGCAGCTGACCAGGCCTATGAGCACTTTATCATTCAGGTGCAGGAGGCCAACAAGGTGGAGGCAGCTCGGAACCTCACCGTGCCTGGCAGCCTTCGGGCTGTGGACATACCGGGCCTCAAGGCTGCTACGCCTTATACAGTCTCCATCTATGGGGTGATCCAGGGCTATAGAACACCAGTGCTCTCTGCTGAGGCCTCCACAGGGGAAACTCCCAATTTGGGAGAGGTCGTGGTGGCCGAGGTGGGCTGGGATGCCCTCAAACTCAACTGGACTGCTCCAGAAGGGGCCTATGAGTACTTTTTCATTCAGGTGCAGGAGGCTGACACAGTAGAGGCAGCCCAGAACCTCACCGTCCCAGGAGGACTGAGGTCCACAGACCTGCCTGGGCTCAAAGCAGCCACTCATTATACCATCACCATCCGCGGGGTCACTCAGGACTTCAGCACAACCCCTCTCTCTGTTGAAGTCTTGACAGAGGAGGTTCCAGATATGGGAAACCTCACAGTGACCGAGGTTAGCTGGGATGCTCTCAGACTGAACTGGACCACGCCAGATGGAACCTATGACCAGTTTACTATTCAGGTCCAGGAGGCTGACCAGGTGGAAGAGGCTCACAATCTCACGGTTCCTGGCAGCCTGCGTTCCATGGAAATCCCAGGCCTCAGGGCTGGCACTCCTTACACAGTCACCCTGCACGGCGAGGTCAGGGGCCACAGCACTCGACCCCTTGCTGTAGAGGTCGTCACAGAGGATCTCCCACAGCTGGGAGATTTAGCCGTGTCTGAGGTTGGCTGGGATGGCCTCAGACTCAACTGGACCGCAGCTGACAATGCCTATGAGCACTTTGTCATTCAGGTGCAGGAGGTCAACAAAGTGGAGGCAGCCCAGAACCTCACGTTGCCTGGCAGCCTCAGGGCTGTGGACATCCCGGGCCTCGAGGCTGCCACGCCTTATAGAGTCTCCATCTATGGGGTGATCCGGGGCTATAGAACACCAGTACTCTCTGCTGAGGCCTCCACAGCCAAAGAACCTGAAATTGGAAACTTAAATGTTTCTGACATAACTCCCGAGAGCTTCAATCTCTCCTGGATGGCTACCGATGGGATCTTCGAGACCTTTACCATTGAAATTATTGATTCCAATAGGTTGCTGGAGACTGTGGAATATAATATCTCTGGTGCTGAACGAACTGCCCATATCTCAGGGCTACCCCCTAGTACTGATTTTATTGTCTACCTCTCTGGACTTGCTCCCAGCATCCGGACCAAAACCATCAGTGCCACAGCCACGACAGAGGCCCTGCCCCTTCTGGAAAACCTAACCATTTCCGACATTAATCCCTACGGGTTCACAGTTTCCTGGATGGCATCGGAGAATGCCTTTGACAGCTTTCTAGTAACGGTGGTGGATTCTGGGAAGCTGCTGGACCCCCAGGAATTCACACTTTCAGGAACCCAGAGGAAGCTGGAGCTTAGAGGCCTCATAACTGGCATTGGCTATGAGGTTATGGTCTCTGGCTTCACCCAAGGGCATCAAACCAAGCCCTTGAGGGCTGAGATTGTTACAGAAGCCGAACCGGAAGTTGACAACCTTCTGGTTTCAGATGCCACCCCAGACGGTTTCCGTCTGTCCTGGACAGCTGATGAAGGGGTCTTCGACAATTTTGTTCTCAAAATCAGAGATACCAAAAAGCAGTCTGAGCCACTGGAAATAACCCTACTTGCCCCCGAACGTACCAGGGACATAACAGGTCTCAGAGAGGCTACTGAATACGAAATTGAACTCTATGGAATAAGCAAAGGAAGGCGATCCCAGACAGTCAGTGCTATAGCAACAACAGCCATGGGCTCCCCAAAGGAAGTCATTTTCTCAGACATCACTGAAAATTCGGCTACTGTCAGCTGGAGGGCACCCACAGCCCAAGTGGAGAGCTTCCGGATTACCTATGTGCCCATTACAGGAGGTACACCCTCCATGGTAACTGTGGACGGAACCAAGACTCAGACCAGGCTGGTGAAACTCATACCTGGCGTGGAGTACCTTGTCAGCATCATCGCCATGAAGGGCTTTGAGGAAAGTGAACCTGTCTCAGGGTCATTCACCACAGCTCTGGATGGCCCATCTGGCCTGGTGACAGCCAACATCACTGACTCAGAAGCCTTGGCCAGGTGGCAGCCAGCCATTGCCACTGTGGACAGTTATGTCATCTCCTACACAGGCGAGAAAGTGCCAGAAATTACACGCACGGTGTCCGGGAACACAGTGGAGTATGCTCTGACCGACCTCGAGCCTGCCACGGAATACACACTGAGAATCTTTGCAGAGAAAGGGCCCCAGAAGAGCTCAACCATCACTGCCAAGTTCACAACAGACCTCGATTCTCCAAGAGACTTGACTGCTACTGAGGTTCAGTCGGAAACTGCCCTCCTTACCTGGCGACCCCCCCGGGCATCAGTCACCGGTTACCTGCTGGTCTATGAATCAGTGGATGGCACAGTCAAGGAAGTCATTGTGGGTCCAGATACCACCTCCTACAGCCTGGCAGACCTGAGCCCATCCACCCACTACACAGCCAAGATCCAGGCACTCAATGGGCCCCTGAGGAGCAATATGATCCAGACCATCTTCACCACAATTGGACTCCTGTACCCCTTCCCCAAGGACTGCTCCCAAGCAATGCTGAATGGAGACACGACCTCTGGCCTCTACACCATTTATCTGAATGGTGATAAGGCTGAGGCGCTGGAAGTCTTCTGTGACATGACCTCTGATGGGGGTGGATGGATTGTGTTCCTGAGACGCAAAAACGGACGCGAGAACTTCTACCAAAACTGGAAGGCATATGCTGCTGGATTTGGGGACCGCAGAGAAGAATTCTGGCTTGGGCTGGACAACCTGAACAAAATCACAGCCCAGGGGCAGTACGAGCTCCGGGTGGACCTGCGGGACCATGGGGAGACAGCCTTTGCTGTCTATGACAAGTTCAGCGTGGGAGATGCCAAGACTCGCTACAAGCTGAAGGTGGAGGGGTACAGTGGGACAGCAGGTGACTCCATGGCCTACCACAATGGCAGATCCTTCTCCACCTTTGACAAGGACACAGATTCAGCCATCACCAACTGTGCTCTGTCCTACAAAGGGGCTTTCTGGTACAGGAACTGTCACCGTGTCAACCTGATGGGGAGATATGGGGACAATAACCACAGTCAGGGCGTTAACTGGTTCCACTGGAAGGGCCACGAACACTCAATCCAGTTTGCTGAGATGAAGCTGAGACCAAGCAACTTCAGAAATCTTGAAGGCAGGCGCAAACGGGCATAA-3'

NCBI CDS gene sequence with introns (location: 115021157.. 115091018) (69862 bp)Download

NCBI Gene Viewer (CDS + introns)

NCBI CDS gene sequence with introns, 5'UTR and 3'UTR (location: 115019575.. 115118157) (98583 bp)Download

NCBI Gene Viewer (CDS + introns + Untranslated regions)

NCBI gene sequence (location: [115019575.. 115118157 + 1000]) (99583 bp)Download

NCBI Gene Viewer (CDS + introns + Untranslated regions + 1000 dNTP to potentially reach the promotor)

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