NCBI Summary
This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration. [provided by RefSeq, Jul 2011].
Protein
Protein (NP_002151)
Tenascin
Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (Tenascin-C) (TN-C)
TNC
tenascin C
Undefined
Very low evidence
Ficolin-like
Undefined
a/b mixed with b-sheet / Fibrinogen C-ter like
Uncharacterised
NP_002151
3371
P24821
ENSP00000265131.4
P24821
0.579
Undefined
PFAM, InterPro, CPX-466
Protein sequence and protein families (fasta) (2201 amino acids) Download
MGAMTQLLAGVFLAFLALATEGGVLKKVIRHKRQSGVNATLPEENQPVVFNHVYNIKLPVGSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRINIPRRACGCAAAPDVKELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEGRRKRA
Mol* PDB structure viewerUniLectin3D
Structural models
AlphaFold v2: AF-P24821-F1Download
  Model Confidence:
  •    Very high (pLDDT > 90)
  •    Confident (90 > pLDDT > 70)
  •    Low (70 > pLDDT > 50)
  •    Very low (pLDDT < 50)

  AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Oligomerization and Known Interactions
Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4 (PubMed:8824254). Interacts (via the 3rd fibronectin type-III domain) with integrin ITGA9:ITGB1 (PubMed:22654117)
Annotation
Ligand
Glycan ligands from structural data
No crystal structures of complexes with glycan ligand.
Expression
Human Protein Atlas
GeneCards
Functionality temporarily unavailable.
ProteomicsDB
References
NCBI References (10 PubMed Identifiers)
  • Functions of Matricellular Proteins in Dental Tissues and Their Emerging Roles in Orofacial Tissue Development, Maintenance, and Disease. [34205668]
  • Tenascin-C immobilizes infiltrating T lymphocytes through CXCL12 promoting breast cancer progression. [33988305]
  • An integrated approach for identification of a panel of candidate genes arbitrated for invasion and metastasis in oral squamous cell carcinoma. [33739025]
  • Extracellular matrix changes in corneal opacification vary depending on etiology. [33633437]
  • Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging. [33217999]
  • Structure and chromosomal localization of the human gene for a brain form of prostaglandin D2 synthase. [1385416]
  • Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein. [1279805]
  • Structure of the human hexabrachion (tenascin) gene. [1719530]
  • The complete cDNA sequence of human hexabrachion (Tenascin). A multidomain protein containing unique epidermal growth factor repeats. [1704365]
  • Human tenascin: primary structure, pre-mRNA splicing patterns and localization of the epitopes recognized by two monoclonal antibodies. [1707164]
UniProt Main References (13 PubMed Identifiers)
  • Human tenascin gene. Structure of the 5'-region, identification, and characterization of the transcription regulatory sequences. [7531707]
  • DNA sequence and analysis of human chromosome 9. [15164053]
  • Analysis of aggrecan and tenascin gene expression in mouse skeletal tissues by northern and in situ hybridization using species specific cDNA probes. [7524681]
  • An alternatively spliced region of the human hexabrachion contains a repeat of potential N-glycosylation sites. [2466295]
  • Binding of the NG2 proteoglycan to type VI collagen and other extracellular matrix molecules. [8824254]
  • Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. [16335952]
  • Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry. [18780401]
  • Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. [19159218]
  • Tenascin-W is a specific marker of glioma-associated blood vessels and stimulates angiogenesis in vitro. [19884327]
  • Initial characterization of the human central proteome. [21269460]
    • Show more
All isoforms of this gene containing a lectin domain
XP_005252032.1, XP_006717164.1, XP_005252031.1, XP_011516930.1, XP_011516931.1, XP_005252030.1, XP_011516928.1, XP_016870170.1, XP_011516927.1, XP_006717161.1, XP_005252029.1, XP_006717160.1, XP_006717159.1, XP_016870168.1, NP_002151.2, XP_016870167.1, XP_024303298.1, XP_016870169.1
RNA
RNA (Transcript ID: NM_002160.4)
NM_002160.4
tenascin C
All isoforms of TNC containing a lectin domain
ENST00000350763.9
313..6918 (or 115021157.. 115091018)
115019575.. 115118157
NCBI Matured mRNA sequence 8500 NTPDownload 
m7G-5')ppp(5'-GGCCACAGCCUGCCUACUGUCACCCGCCUCUCCCGCGCGCAGAUACACGCCCCCGCCUCCGUGGGCACAAAGGCAGCGCUGCUGGGGAACUCGGGGGAACGCGCACGUGGGAACCGCCGCAGCUCCACACUCCAGGUACUUCUUCCAAGGACCUAGGUCUCUCGCCCAUCGGAAAGAAAAUAAUUCUUUCAAGAAGAUCAGGGACAACUGAUUUGAAGUCUACUCUGUGCUUCUAAAUCCCCAAUUCUGCUGAAAGUGAGAUACCCUAGAGCCCUAGAGCCCCAGCAGCACCCAGCCAAACCCACCUCCACCAUGGGGGCCAUGACUCAGCUGUUGGCAGGUGUCUUUCUUGCUUUCCUUGCCCUCGCUACCGAAGGUGGGGUCCUCAAGAAAGUCAUCCGGCACAAGCGACAGAGUGGGGUGAACGCCACCCUGCCAGAAGAGAACCAGCCAGUGGUGUUUAACCACGUUUACAACAUCAAGCUGCCAGUGGGAUCCCAGUGUUCGGUGGAUCUGGAGUCAGCCAGUGGGGAGAAAGACCUGGCACCGCCUUCAGAGCCCAGCGAAAGCUUUCAGGAGCACACAGUGGAUGGGGAAAACCAGAUUGUCUUCACACAUCGCAUCAACAUCCCCCGCCGGGCCUGUGGCUGUGCCGCAGCCCCUGAUGUUAAGGAGCUGCUGAGCAGACUGGAGGAGCUGGAGAACCUGGUGUCUUCCCUGAGGGAGCAAUGUACUGCAGGAGCAGGCUGCUGUCUCCAGCCUGCCACAGGCCGCUUGGACACCAGGCCCUUCUGUAGCGGUCGGGGCAACUUCAGCACUGAAGGAUGUGGCUGUGUCUGCGAACCUGGCUGGAAAGGCCCCAACUGCUCUGAGCCCGAAUGUCCAGGCAACUGUCACCUUCGAGGCCGGUGCAUUGAUGGGCAGUGCAUCUGUGACGACGGCUUCACGGGCGAGGACUGCAGCCAGCUGGCUUGCCCCAGCGACUGCAAUGACCAGGGCAAGUGCGUAAAUGGAGUCUGCAUCUGUUUCGAAGGCUACGCCGGGGCUGACUGCAGCCGUGAAAUCUGCCCAGUGCCCUGCAGUGAGGAGCACGGCACAUGUGUAGAUGGCUUGUGUGUGUGCCACGAUGGCUUUGCAGGCGAUGACUGCAACAAGCCUCUGUGUCUCAACAAUUGCUACAACCGUGGACGAUGCGUGGAGAAUGAGUGCGUGUGUGAUGAGGGUUUCACGGGCGAAGACUGCAGUGAGCUCAUCUGCCCCAAUGACUGCUUCGACCGGGGCCGCUGCAUCAAUGGCACCUGCUACUGCGAAGAAGGCUUCACAGGUGAAGACUGCGGGAAACCCACCUGCCCACAUGCCUGCCACACCCAGGGCCGGUGUGAGGAGGGGCAGUGUGUAUGUGAUGAGGGCUUUGCCGGUGUGGACUGCAGCGAGAAGAGGUGUCCUGCUGACUGUCACAAUCGUGGCCGCUGUGUAGACGGGCGGUGUGAGUGUGAUGAUGGUUUCACUGGAGCUGACUGUGGGGAGCUCAAGUGUCCCAAUGGCUGCAGUGGCCAUGGCCGCUGUGUCAAUGGGCAGUGUGUGUGUGAUGAGGGCUAUACUGGGGAGGACUGCAGCCAGCUACGGUGCCCCAAUGACUGUCACAGUCGGGGCCGCUGUGUCGAGGGCAAAUGUGUAUGUGAGCAAGGCUUCAAGGGCUAUGACUGCAGUGACAUGAGCUGCCCUAAUGACUGUCACCAGCACGGCCGCUGUGUGAAUGGCAUGUGUGUUUGUGAUGACGGCUACACAGGGGAAGACUGCCGGGAUCGCCAAUGCCCCAGGGACUGCAGCAACAGGGGCCUCUGUGUGGACGGACAGUGCGUCUGUGAGGACGGCUUCACCGGCCCUGACUGUGCAGAACUCUCCUGUCCAAAUGACUGCCAUGGCCAGGGUCGCUGUGUGAAUGGGCAGUGCGUGUGCCAUGAAGGAUUUAUGGGCAAAGACUGCAAGGAGCAAAGAUGUCCCAGUGACUGUCAUGGCCAGGGCCGCUGCGUGGACGGCCAGUGCAUCUGCCACGAGGGCUUCACAGGCCUGGACUGUGGCCAGCACUCCUGCCCCAGUGACUGCAACAACUUAGGACAAUGCGUCUCGGGCCGCUGCAUCUGCAACGAGGGCUACAGCGGAGAAGACUGCUCAGAGGUGUCUCCUCCCAAAGACCUCGUUGUGACAGAAGUGACGGAAGAGACGGUCAACCUGGCCUGGGACAAUGAGAUGCGGGUCACAGAGUACCUUGUCGUGUACACGCCCACCCACGAGGGUGGUCUGGAAAUGCAGUUCCGUGUGCCUGGGGACCAGACGUCCACCAUCAUCCAGGAGCUGGAGCCUGGUGUGGAGUACUUUAUCCGUGUAUUUGCCAUCCUGGAGAACAAGAAGAGCAUUCCUGUCAGCGCCAGGGUGGCCACGUACUUACCUGCACCUGAAGGCCUGAAAUUCAAGUCCAUCAAGGAGACAUCUGUGGAAGUGGAGUGGGAUCCUCUAGACAUUGCUUUUGAAACCUGGGAGAUCAUCUUCCGGAAUAUGAAUAAAGAAGAUGAGGGAGAGAUCACCAAAAGCCUGAGGAGGCCAGAGACCUCUUACCGGCAAACUGGUCUAGCUCCUGGGCAAGAGUAUGAGAUAUCUCUGCACAUAGUGAAAAACAAUACCCGGGGCCCUGGCCUGAAGAGGGUGACCACCACACGCUUGGAUGCCCCCAGCCAGAUCGAGGUGAAAGAUGUCACAGACACCACUGCCUUGAUCACCUGGUUCAAGCCCCUGGCUGAGAUCGAUGGCAUUGAGCUGACCUACGGCAUCAAAGACGUGCCAGGAGACCGUACCACCAUCGAUCUCACAGAGGACGAGAACCAGUACUCCAUCGGGAACCUGAAGCCUGACACUGAGUACGAGGUGUCCCUCAUCUCCCGCAGAGGUGACAUGUCAAGCAACCCAGCCAAAGAGACCUUCACAACAGGCCUCGAUGCUCCCAGGAAUCUUCGACGUGUUUCCCAGACAGAUAACAGCAUCACCCUGGAAUGGAGGAAUGGCAAGGCAGCUAUUGACAGUUACAGAAUUAAGUAUGCCCCCAUCUCUGGAGGGGACCACGCUGAGGUUGAUGUUCCAAAGAGCCAACAAGCCACAACCAAAACCACACUCACAGGUCUGAGGCCGGGAACUGAAUAUGGGAUUGGAGUUUCUGCUGUGAAGGAAGACAAGGAGAGCAAUCCAGCGACCAUCAACGCAGCCACAGAGUUGGACACGCCCAAGGACCUUCAGGUUUCUGAAACUGCAGAGACCAGCCUGACCCUGCUCUGGAAGACACCGUUGGCCAAAUUUGACCGCUACCGCCUCAAUUACAGUCUCCCCACAGGCCAGUGGGUGGGAGUGCAGCUUCCAAGAAACACCACUUCCUAUGUCCUGAGAGGCCUGGAACCAGGACAGGAGUACAAUGUCCUCCUGACAGCCGAGAAAGGCAGACACAAGAGCAAGCCCGCACGUGUGAAGGCAUCCACUGAACAAGCCCCUGAGCUGGAAAACCUCACCGUGACUGAGGUUGGCUGGGAUGGCCUCAGACUCAACUGGACCGCAGCUGACCAGGCCUAUGAGCACUUUAUCAUUCAGGUGCAGGAGGCCAACAAGGUGGAGGCAGCUCGGAACCUCACCGUGCCUGGCAGCCUUCGGGCUGUGGACAUACCGGGCCUCAAGGCUGCUACGCCUUAUACAGUCUCCAUCUAUGGGGUGAUCCAGGGCUAUAGAACACCAGUGCUCUCUGCUGAGGCCUCCACAGGGGAAACUCCCAAUUUGGGAGAGGUCGUGGUGGCCGAGGUGGGCUGGGAUGCCCUCAAACUCAACUGGACUGCUCCAGAAGGGGCCUAUGAGUACUUUUUCAUUCAGGUGCAGGAGGCUGACACAGUAGAGGCAGCCCAGAACCUCACCGUCCCAGGAGGACUGAGGUCCACAGACCUGCCUGGGCUCAAAGCAGCCACUCAUUAUACCAUCACCAUCCGCGGGGUCACUCAGGACUUCAGCACAACCCCUCUCUCUGUUGAAGUCUUGACAGAGGAGGUUCCAGAUAUGGGAAACCUCACAGUGACCGAGGUUAGCUGGGAUGCUCUCAGACUGAACUGGACCACGCCAGAUGGAACCUAUGACCAGUUUACUAUUCAGGUCCAGGAGGCUGACCAGGUGGAAGAGGCUCACAAUCUCACGGUUCCUGGCAGCCUGCGUUCCAUGGAAAUCCCAGGCCUCAGGGCUGGCACUCCUUACACAGUCACCCUGCACGGCGAGGUCAGGGGCCACAGCACUCGACCCCUUGCUGUAGAGGUCGUCACAGAGGAUCUCCCACAGCUGGGAGAUUUAGCCGUGUCUGAGGUUGGCUGGGAUGGCCUCAGACUCAACUGGACCGCAGCUGACAAUGCCUAUGAGCACUUUGUCAUUCAGGUGCAGGAGGUCAACAAAGUGGAGGCAGCCCAGAACCUCACGUUGCCUGGCAGCCUCAGGGCUGUGGACAUCCCGGGCCUCGAGGCUGCCACGCCUUAUAGAGUCUCCAUCUAUGGGGUGAUCCGGGGCUAUAGAACACCAGUACUCUCUGCUGAGGCCUCCACAGCCAAAGAACCUGAAAUUGGAAACUUAAAUGUUUCUGACAUAACUCCCGAGAGCUUCAAUCUCUCCUGGAUGGCUACCGAUGGGAUCUUCGAGACCUUUACCAUUGAAAUUAUUGAUUCCAAUAGGUUGCUGGAGACUGUGGAAUAUAAUAUCUCUGGUGCUGAACGAACUGCCCAUAUCUCAGGGCUACCCCCUAGUACUGAUUUUAUUGUCUACCUCUCUGGACUUGCUCCCAGCAUCCGGACCAAAACCAUCAGUGCCACAGCCACGACAGAGGCCCUGCCCCUUCUGGAAAACCUAACCAUUUCCGACAUUAAUCCCUACGGGUUCACAGUUUCCUGGAUGGCAUCGGAGAAUGCCUUUGACAGCUUUCUAGUAACGGUGGUGGAUUCUGGGAAGCUGCUGGACCCCCAGGAAUUCACACUUUCAGGAACCCAGAGGAAGCUGGAGCUUAGAGGCCUCAUAACUGGCAUUGGCUAUGAGGUUAUGGUCUCUGGCUUCACCCAAGGGCAUCAAACCAAGCCCUUGAGGGCUGAGAUUGUUACAGAAGCCGAACCGGAAGUUGACAACCUUCUGGUUUCAGAUGCCACCCCAGACGGUUUCCGUCUGUCCUGGACAGCUGAUGAAGGGGUCUUCGACAAUUUUGUUCUCAAAAUCAGAGAUACCAAAAAGCAGUCUGAGCCACUGGAAAUAACCCUACUUGCCCCCGAACGUACCAGGGACAUAACAGGUCUCAGAGAGGCUACUGAAUACGAAAUUGAACUCUAUGGAAUAAGCAAAGGAAGGCGAUCCCAGACAGUCAGUGCUAUAGCAACAACAGCCAUGGGCUCCCCAAAGGAAGUCAUUUUCUCAGACAUCACUGAAAAUUCGGCUACUGUCAGCUGGAGGGCACCCACAGCCCAAGUGGAGAGCUUCCGGAUUACCUAUGUGCCCAUUACAGGAGGUACACCCUCCAUGGUAACUGUGGACGGAACCAAGACUCAGACCAGGCUGGUGAAACUCAUACCUGGCGUGGAGUACCUUGUCAGCAUCAUCGCCAUGAAGGGCUUUGAGGAAAGUGAACCUGUCUCAGGGUCAUUCACCACAGCUCUGGAUGGCCCAUCUGGCCUGGUGACAGCCAACAUCACUGACUCAGAAGCCUUGGCCAGGUGGCAGCCAGCCAUUGCCACUGUGGACAGUUAUGUCAUCUCCUACACAGGCGAGAAAGUGCCAGAAAUUACACGCACGGUGUCCGGGAACACAGUGGAGUAUGCUCUGACCGACCUCGAGCCUGCCACGGAAUACACACUGAGAAUCUUUGCAGAGAAAGGGCCCCAGAAGAGCUCAACCAUCACUGCCAAGUUCACAACAGACCUCGAUUCUCCAAGAGACUUGACUGCUACUGAGGUUCAGUCGGAAACUGCCCUCCUUACCUGGCGACCCCCCCGGGCAUCAGUCACCGGUUACCUGCUGGUCUAUGAAUCAGUGGAUGGCACAGUCAAGGAAGUCAUUGUGGGUCCAGAUACCACCUCCUACAGCCUGGCAGACCUGAGCCCAUCCACCCACUACACAGCCAAGAUCCAGGCACUCAAUGGGCCCCUGAGGAGCAAUAUGAUCCAGACCAUCUUCACCACAAUUGGACUCCUGUACCCCUUCCCCAAGGACUGCUCCCAAGCAAUGCUGAAUGGAGACACGACCUCUGGCCUCUACACCAUUUAUCUGAAUGGUGAUAAGGCUGAGGCGCUGGAAGUCUUCUGUGACAUGACCUCUGAUGGGGGUGGAUGGAUUGUGUUCCUGAGACGCAAAAACGGACGCGAGAACUUCUACCAAAACUGGAAGGCAUAUGCUGCUGGAUUUGGGGACCGCAGAGAAGAAUUCUGGCUUGGGCUGGACAACCUGAACAAAAUCACAGCCCAGGGGCAGUACGAGCUCCGGGUGGACCUGCGGGACCAUGGGGAGACAGCCUUUGCUGUCUAUGACAAGUUCAGCGUGGGAGAUGCCAAGACUCGCUACAAGCUGAAGGUGGAGGGGUACAGUGGGACAGCAGGUGACUCCAUGGCCUACCACAAUGGCAGAUCCUUCUCCACCUUUGACAAGGACACAGAUUCAGCCAUCACCAACUGUGCUCUGUCCUACAAAGGGGCUUUCUGGUACAGGAACUGUCACCGUGUCAACCUGAUGGGGAGAUAUGGGGACAAUAACCACAGUCAGGGCGUUAACUGGUUCCACUGGAAGGGCCACGAACACUCAAUCCAGUUUGCUGAGAUGAAGCUGAGACCAAGCAACUUCAGAAAUCUUGAAGGCAGGCGCAAACGGGCAUAAAUUCCAGGGACCACUGGGUGAGAGAGGAAUAAGGCCCAGAGCGAGGAAAGGAUUUUACCAAAGCAUCAAUACAACCAGCCCAACCAUCGGUCCACACCUGGGCAUUUGGUGAGAGUCAAAGCUGACCAUGGAUCCCUGGGGCCAACGGCAACAGCAUGGGCCUCACCUCCUCUGUGAUUUCUUUCUUUGCACCAAAGACAUCAGUCUCCAACAUGUUUCUGUUUUGUUGUUUGAUUCAGCAAAAAUCUCCCAGUGACAACAUCGCAAUAGUUUUUUACUUCUCUUAGGUGGCUCUGGGAAUGGGAGAGGGGUAGGAUGUACAGGGGUAGUUUGUUUUAGAACCAGCCGUAUUUUACAUGAAGCUGUAUAAUUAAUUGUCAUUAUUUUUGUUAGCAAAGAUUAAAUGUGUCAUUGGAAGCCAUCCCUUUUUUUACAUUUCAUACAACAGAAACCAGAAAAGCAAUACUGUUUCCAUUUUAAGGAUAUGAUUAAUAUUAUUAAUAUAAUAAUGAUGAUGAUGAUGAUGAAAACUAAGGAUUUUUCAAGAGAUCUUUCUUUCCAAAACAUUUCUGGACAGUACCUGAUUGUAUUUUUUUUUUAAAUAAAAGCACAAGUACUUUUGAGUUUGUUAUUUUGCUUUGAAUUGUUGAGUCUGAAUUUCACCAAAGCCAAUCAUUUGAACAAAGCGGGGAAUGUUGGGAUAGGAAAGGUAAGUAGGGAUAGUGGUCAAGUGGGAGGGGUGGAAAGGAGACUAAAGACUGGGAGAGAGGGAAGCACUUUUUUUAAAUAAAGUUGAACACACUUGGGAAAAGCUUACAGGCCAGGCCUGUAAUCCCAACACUUUGGGAGGCCAAGGUGGGAGGAUAGCUUAACCCCAGGAGUUUGAGACCAGCCUGAGCAACAUAGUGAGAACUUGUCUCUACAGAAAAAAAAAAAAAAAAAAAUUUAAUUAGGCAAGCGUGGUAGUGCGCACCUGUCGUCCCAGCUACUCAGGAGGCUGAGGUAGGAAAAUCACUGGAGCCCAGGAGUUAGAGGUUACAGUGAGCUAUGAUCACACUACUGCACUCCAGCCUGGGCAACAGAGGGAGACCCUGUCUCUAAAUAAAAAAAGAAAAGAAAAAAAAAGCUUACAACUUGAGAUUCAGCAUCUUGCUCAGUAUUUCCAAGACUAAUAGAUUAUGGUUUAAAAGAUGCUUUUAUACUCAUUUUCUAAUGCAACUCCUAGAAACUCUAUGAUAUAGUUGAGGUAAGUAUUGUUACCACACAUGGGCUAAGAUCCCCAGAGGCAGACUGCCUGAGUUCAAUUCUUGGCUCCACCAUUCCCAAGUUCCCUAACCUCUCUAUGCCUCAGUUUCCUCUUCUGUAAAGUAGGGACACUCAUACUUCUCAUUUCAGAACAUUUUUGUGAAGAAUAAAUUAUGUUAUCCAUUUGAGGCCCUUAGAAUGGUACCCGGUGUAUAUUAAGUGCUAGUACAUGUUAGCUAUCAUCAUUAUCACUUUAUAUGAGAUGGACUGGGGUUCAUAGAAACCCAAUGACUUGAUUGUGGCUACUACUCAAUAAAUAAUAGAAUUUGGAUUUAAA-3'- Poly-A tail
  • Coding region
mRNA-related data
DNA
DNA (Gene ID: 3371)
TNC
tenascin C
NC_000009.12
9  115021157.. 115091018
115021157.. 115091018
strand -
CCDS6811.1
MGI:101922
ClinVar, dbVar
ENSG00000041982
TN, MGC167029
uc004bjj.6
INSDC:
5318
187380
OTTHUMG00000021010
ENA, DDBJ, Monarch
Gene-related data
NCBI CDS gene sequence (6606 bp)
5'-ATGGGGGCCATGACTCAGCTGTTGGCAGGTGTCTTTCTTGCTTTCCTTGCCCTCGCTACCGAAGGTGGGGTCCTCAAGAAAGTCATCCGGCACAAGCGACAGAGTGGGGTGAACGCCACCCTGCCAGAAGAGAACCAGCCAGTGGTGTTTAACCACGTTTACAACATCAAGCTGCCAGTGGGATCCCAGTGTTCGGTGGATCTGGAGTCAGCCAGTGGGGAGAAAGACCTGGCACCGCCTTCAGAGCCCAGCGAAAGCTTTCAGGAGCACACAGTGGATGGGGAAAACCAGATTGTCTTCACACATCGCATCAACATCCCCCGCCGGGCCTGTGGCTGTGCCGCAGCCCCTGATGTTAAGGAGCTGCTGAGCAGACTGGAGGAGCTGGAGAACCTGGTGTCTTCCCTGAGGGAGCAATGTACTGCAGGAGCAGGCTGCTGTCTCCAGCCTGCCACAGGCCGCTTGGACACCAGGCCCTTCTGTAGCGGTCGGGGCAACTTCAGCACTGAAGGATGTGGCTGTGTCTGCGAACCTGGCTGGAAAGGCCCCAACTGCTCTGAGCCCGAATGTCCAGGCAACTGTCACCTTCGAGGCCGGTGCATTGATGGGCAGTGCATCTGTGACGACGGCTTCACGGGCGAGGACTGCAGCCAGCTGGCTTGCCCCAGCGACTGCAATGACCAGGGCAAGTGCGTAAATGGAGTCTGCATCTGTTTCGAAGGCTACGCCGGGGCTGACTGCAGCCGTGAAATCTGCCCAGTGCCCTGCAGTGAGGAGCACGGCACATGTGTAGATGGCTTGTGTGTGTGCCACGATGGCTTTGCAGGCGATGACTGCAACAAGCCTCTGTGTCTCAACAATTGCTACAACCGTGGACGATGCGTGGAGAATGAGTGCGTGTGTGATGAGGGTTTCACGGGCGAAGACTGCAGTGAGCTCATCTGCCCCAATGACTGCTTCGACCGGGGCCGCTGCATCAATGGCACCTGCTACTGCGAAGAAGGCTTCACAGGTGAAGACTGCGGGAAACCCACCTGCCCACATGCCTGCCACACCCAGGGCCGGTGTGAGGAGGGGCAGTGTGTATGTGATGAGGGCTTTGCCGGTGTGGACTGCAGCGAGAAGAGGTGTCCTGCTGACTGTCACAATCGTGGCCGCTGTGTAGACGGGCGGTGTGAGTGTGATGATGGTTTCACTGGAGCTGACTGTGGGGAGCTCAAGTGTCCCAATGGCTGCAGTGGCCATGGCCGCTGTGTCAATGGGCAGTGTGTGTGTGATGAGGGCTATACTGGGGAGGACTGCAGCCAGCTACGGTGCCCCAATGACTGTCACAGTCGGGGCCGCTGTGTCGAGGGCAAATGTGTATGTGAGCAAGGCTTCAAGGGCTATGACTGCAGTGACATGAGCTGCCCTAATGACTGTCACCAGCACGGCCGCTGTGTGAATGGCATGTGTGTTTGTGATGACGGCTACACAGGGGAAGACTGCCGGGATCGCCAATGCCCCAGGGACTGCAGCAACAGGGGCCTCTGTGTGGACGGACAGTGCGTCTGTGAGGACGGCTTCACCGGCCCTGACTGTGCAGAACTCTCCTGTCCAAATGACTGCCATGGCCAGGGTCGCTGTGTGAATGGGCAGTGCGTGTGCCATGAAGGATTTATGGGCAAAGACTGCAAGGAGCAAAGATGTCCCAGTGACTGTCATGGCCAGGGCCGCTGCGTGGACGGCCAGTGCATCTGCCACGAGGGCTTCACAGGCCTGGACTGTGGCCAGCACTCCTGCCCCAGTGACTGCAACAACTTAGGACAATGCGTCTCGGGCCGCTGCATCTGCAACGAGGGCTACAGCGGAGAAGACTGCTCAGAGGTGTCTCCTCCCAAAGACCTCGTTGTGACAGAAGTGACGGAAGAGACGGTCAACCTGGCCTGGGACAATGAGATGCGGGTCACAGAGTACCTTGTCGTGTACACGCCCACCCACGAGGGTGGTCTGGAAATGCAGTTCCGTGTGCCTGGGGACCAGACGTCCACCATCATCCAGGAGCTGGAGCCTGGTGTGGAGTACTTTATCCGTGTATTTGCCATCCTGGAGAACAAGAAGAGCATTCCTGTCAGCGCCAGGGTGGCCACGTACTTACCTGCACCTGAAGGCCTGAAATTCAAGTCCATCAAGGAGACATCTGTGGAAGTGGAGTGGGATCCTCTAGACATTGCTTTTGAAACCTGGGAGATCATCTTCCGGAATATGAATAAAGAAGATGAGGGAGAGATCACCAAAAGCCTGAGGAGGCCAGAGACCTCTTACCGGCAAACTGGTCTAGCTCCTGGGCAAGAGTATGAGATATCTCTGCACATAGTGAAAAACAATACCCGGGGCCCTGGCCTGAAGAGGGTGACCACCACACGCTTGGATGCCCCCAGCCAGATCGAGGTGAAAGATGTCACAGACACCACTGCCTTGATCACCTGGTTCAAGCCCCTGGCTGAGATCGATGGCATTGAGCTGACCTACGGCATCAAAGACGTGCCAGGAGACCGTACCACCATCGATCTCACAGAGGACGAGAACCAGTACTCCATCGGGAACCTGAAGCCTGACACTGAGTACGAGGTGTCCCTCATCTCCCGCAGAGGTGACATGTCAAGCAACCCAGCCAAAGAGACCTTCACAACAGGCCTCGATGCTCCCAGGAATCTTCGACGTGTTTCCCAGACAGATAACAGCATCACCCTGGAATGGAGGAATGGCAAGGCAGCTATTGACAGTTACAGAATTAAGTATGCCCCCATCTCTGGAGGGGACCACGCTGAGGTTGATGTTCCAAAGAGCCAACAAGCCACAACCAAAACCACACTCACAGGTCTGAGGCCGGGAACTGAATATGGGATTGGAGTTTCTGCTGTGAAGGAAGACAAGGAGAGCAATCCAGCGACCATCAACGCAGCCACAGAGTTGGACACGCCCAAGGACCTTCAGGTTTCTGAAACTGCAGAGACCAGCCTGACCCTGCTCTGGAAGACACCGTTGGCCAAATTTGACCGCTACCGCCTCAATTACAGTCTCCCCACAGGCCAGTGGGTGGGAGTGCAGCTTCCAAGAAACACCACTTCCTATGTCCTGAGAGGCCTGGAACCAGGACAGGAGTACAATGTCCTCCTGACAGCCGAGAAAGGCAGACACAAGAGCAAGCCCGCACGTGTGAAGGCATCCACTGAACAAGCCCCTGAGCTGGAAAACCTCACCGTGACTGAGGTTGGCTGGGATGGCCTCAGACTCAACTGGACCGCAGCTGACCAGGCCTATGAGCACTTTATCATTCAGGTGCAGGAGGCCAACAAGGTGGAGGCAGCTCGGAACCTCACCGTGCCTGGCAGCCTTCGGGCTGTGGACATACCGGGCCTCAAGGCTGCTACGCCTTATACAGTCTCCATCTATGGGGTGATCCAGGGCTATAGAACACCAGTGCTCTCTGCTGAGGCCTCCACAGGGGAAACTCCCAATTTGGGAGAGGTCGTGGTGGCCGAGGTGGGCTGGGATGCCCTCAAACTCAACTGGACTGCTCCAGAAGGGGCCTATGAGTACTTTTTCATTCAGGTGCAGGAGGCTGACACAGTAGAGGCAGCCCAGAACCTCACCGTCCCAGGAGGACTGAGGTCCACAGACCTGCCTGGGCTCAAAGCAGCCACTCATTATACCATCACCATCCGCGGGGTCACTCAGGACTTCAGCACAACCCCTCTCTCTGTTGAAGTCTTGACAGAGGAGGTTCCAGATATGGGAAACCTCACAGTGACCGAGGTTAGCTGGGATGCTCTCAGACTGAACTGGACCACGCCAGATGGAACCTATGACCAGTTTACTATTCAGGTCCAGGAGGCTGACCAGGTGGAAGAGGCTCACAATCTCACGGTTCCTGGCAGCCTGCGTTCCATGGAAATCCCAGGCCTCAGGGCTGGCACTCCTTACACAGTCACCCTGCACGGCGAGGTCAGGGGCCACAGCACTCGACCCCTTGCTGTAGAGGTCGTCACAGAGGATCTCCCACAGCTGGGAGATTTAGCCGTGTCTGAGGTTGGCTGGGATGGCCTCAGACTCAACTGGACCGCAGCTGACAATGCCTATGAGCACTTTGTCATTCAGGTGCAGGAGGTCAACAAAGTGGAGGCAGCCCAGAACCTCACGTTGCCTGGCAGCCTCAGGGCTGTGGACATCCCGGGCCTCGAGGCTGCCACGCCTTATAGAGTCTCCATCTATGGGGTGATCCGGGGCTATAGAACACCAGTACTCTCTGCTGAGGCCTCCACAGCCAAAGAACCTGAAATTGGAAACTTAAATGTTTCTGACATAACTCCCGAGAGCTTCAATCTCTCCTGGATGGCTACCGATGGGATCTTCGAGACCTTTACCATTGAAATTATTGATTCCAATAGGTTGCTGGAGACTGTGGAATATAATATCTCTGGTGCTGAACGAACTGCCCATATCTCAGGGCTACCCCCTAGTACTGATTTTATTGTCTACCTCTCTGGACTTGCTCCCAGCATCCGGACCAAAACCATCAGTGCCACAGCCACGACAGAGGCCCTGCCCCTTCTGGAAAACCTAACCATTTCCGACATTAATCCCTACGGGTTCACAGTTTCCTGGATGGCATCGGAGAATGCCTTTGACAGCTTTCTAGTAACGGTGGTGGATTCTGGGAAGCTGCTGGACCCCCAGGAATTCACACTTTCAGGAACCCAGAGGAAGCTGGAGCTTAGAGGCCTCATAACTGGCATTGGCTATGAGGTTATGGTCTCTGGCTTCACCCAAGGGCATCAAACCAAGCCCTTGAGGGCTGAGATTGTTACAGAAGCCGAACCGGAAGTTGACAACCTTCTGGTTTCAGATGCCACCCCAGACGGTTTCCGTCTGTCCTGGACAGCTGATGAAGGGGTCTTCGACAATTTTGTTCTCAAAATCAGAGATACCAAAAAGCAGTCTGAGCCACTGGAAATAACCCTACTTGCCCCCGAACGTACCAGGGACATAACAGGTCTCAGAGAGGCTACTGAATACGAAATTGAACTCTATGGAATAAGCAAAGGAAGGCGATCCCAGACAGTCAGTGCTATAGCAACAACAGCCATGGGCTCCCCAAAGGAAGTCATTTTCTCAGACATCACTGAAAATTCGGCTACTGTCAGCTGGAGGGCACCCACAGCCCAAGTGGAGAGCTTCCGGATTACCTATGTGCCCATTACAGGAGGTACACCCTCCATGGTAACTGTGGACGGAACCAAGACTCAGACCAGGCTGGTGAAACTCATACCTGGCGTGGAGTACCTTGTCAGCATCATCGCCATGAAGGGCTTTGAGGAAAGTGAACCTGTCTCAGGGTCATTCACCACAGCTCTGGATGGCCCATCTGGCCTGGTGACAGCCAACATCACTGACTCAGAAGCCTTGGCCAGGTGGCAGCCAGCCATTGCCACTGTGGACAGTTATGTCATCTCCTACACAGGCGAGAAAGTGCCAGAAATTACACGCACGGTGTCCGGGAACACAGTGGAGTATGCTCTGACCGACCTCGAGCCTGCCACGGAATACACACTGAGAATCTTTGCAGAGAAAGGGCCCCAGAAGAGCTCAACCATCACTGCCAAGTTCACAACAGACCTCGATTCTCCAAGAGACTTGACTGCTACTGAGGTTCAGTCGGAAACTGCCCTCCTTACCTGGCGACCCCCCCGGGCATCAGTCACCGGTTACCTGCTGGTCTATGAATCAGTGGATGGCACAGTCAAGGAAGTCATTGTGGGTCCAGATACCACCTCCTACAGCCTGGCAGACCTGAGCCCATCCACCCACTACACAGCCAAGATCCAGGCACTCAATGGGCCCCTGAGGAGCAATATGATCCAGACCATCTTCACCACAATTGGACTCCTGTACCCCTTCCCCAAGGACTGCTCCCAAGCAATGCTGAATGGAGACACGACCTCTGGCCTCTACACCATTTATCTGAATGGTGATAAGGCTGAGGCGCTGGAAGTCTTCTGTGACATGACCTCTGATGGGGGTGGATGGATTGTGTTCCTGAGACGCAAAAACGGACGCGAGAACTTCTACCAAAACTGGAAGGCATATGCTGCTGGATTTGGGGACCGCAGAGAAGAATTCTGGCTTGGGCTGGACAACCTGAACAAAATCACAGCCCAGGGGCAGTACGAGCTCCGGGTGGACCTGCGGGACCATGGGGAGACAGCCTTTGCTGTCTATGACAAGTTCAGCGTGGGAGATGCCAAGACTCGCTACAAGCTGAAGGTGGAGGGGTACAGTGGGACAGCAGGTGACTCCATGGCCTACCACAATGGCAGATCCTTCTCCACCTTTGACAAGGACACAGATTCAGCCATCACCAACTGTGCTCTGTCCTACAAAGGGGCTTTCTGGTACAGGAACTGTCACCGTGTCAACCTGATGGGGAGATATGGGGACAATAACCACAGTCAGGGCGTTAACTGGTTCCACTGGAAGGGCCACGAACACTCAATCCAGTTTGCTGAGATGAAGCTGAGACCAAGCAACTTCAGAAATCTTGAAGGCAGGCGCAAACGGGCATAA-3'
NCBI CDS gene sequence with introns (location: 115021157.. 115091018) (69862 bp)Download
NCBI Gene Viewer (CDS + introns)
NCBI CDS gene sequence with introns, 5'UTR and 3'UTR (location: 115019575.. 115118157) (98583 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions)
NCBI gene sequence (location: [115019575.. 115118157 + 1000]) (99583 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions + 1000 dNTP to potentially reach the promotor)
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