NCBI Summary
This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Protein
Protein (NP_001191047)
Prolectin
C-type lectin domain family 17, member A (Prolectin)
CLEC17A
C-type lectin domain containing 17A
Undefined
Curated
C-type lectin
CLEC17A
C-type - Others
a/b mixed / C-type lectin-like
Man, Fuc / Lewis oligosaccharides
0.39
MHNLYSITGYPDPPGTMEEEEEDDDYENSTPPYKDLPPKPGTMEEEEEDDDYENSTPPYKDLPPKPGTMEEEEEDDDYENSTPPYKDLPPKPGSSAPPRPPRAAKETEKPPLPCKPRNMTGLDLAAVTCPPPQLAVNLEPSPLQPSLAATPVPWLNQRSGGPGCCQKRWMVYLCLLVVTSLFLGCLGLTVTLIKYQELMEELRMLSFQQMTWRTNMTGMAGLAGLKHDIARVRADTNQSLVELWGLLDCRRITCPEGWLPFEGKCYYFSPSTKSWDEARMFCQENYSHLVIINSFAEHNFVAKAHGSPRVYWLGLNDRAQEGDWRWLDGSPVTLSFWEPEEPNNIHDEDCATMNKGGTWNDLSCYKTTYWICERKCSC
No structure currently available in the PDB RCSB Databank.
Structural models
SWISS-MODEL structural models
The location of the lectin domain structural model is: 251-376
We infer [1.35, 1.66] Å as the interval of error of this structural model.
Template 1: 3WH3 chain: A, Q9ULY5, NP_055173.1, sequence identity: 42.9%, coverage: 97.6%, location in sequence: 79-208, (79-208 in PDB).
Template 2: 1K9J chain: A, Q9H2X3, NP_055072.3, sequence identity: 41.3%, coverage: 97.6%, location in sequence: 267-394, (267-394 in PDB).
Template 3: 6PY1 chain: A, Q8IUN9, NP_878910.1, sequence identity: 41.3%, coverage: 96.8%, location in sequence: 179-308, (179-308 in PDB).
Show the alignment used for the construction of the structural model, Download.
Show the plot of DOPE energy score, Download.
We infer [1.35, 1.66] Å as the interval of error of this structural model.
Template 1: 3WH3 chain: A, Q9ULY5, NP_055173.1, sequence identity: 42.9%, coverage: 97.6%, location in sequence: 79-208, (79-208 in PDB).
Template 2: 1K9J chain: A, Q9H2X3, NP_055072.3, sequence identity: 41.3%, coverage: 97.6%, location in sequence: 267-394, (267-394 in PDB).
Template 3: 6PY1 chain: A, Q8IUN9, NP_878910.1, sequence identity: 41.3%, coverage: 96.8%, location in sequence: 179-308, (179-308 in PDB).
Show the alignment used for the construction of the structural model, Download.
Show the plot of DOPE energy score, Download.
Ligand
Glycan ligands from structural data
No crystal structures of complexes with glycan ligand.
References
NCBI References (4 PubMed Identifiers)
- A reference map of the human binary protein interactome. [32296183]
- Carcinoma-associated fucosylated antigens are markers of the epithelial state and can contribute to cell adhesion through CLEC17A (Prolectin). [26908442]
- Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. [23453885]
- Prolectin, a glycan-binding receptor on dividing B cells in germinal centers. [19419970]
UniProt Main References (3 PubMed Identifiers)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. [14702039]
- The DNA sequence and biology of human chromosome 19. [15057824]
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). [15489334]
All isoforms of this gene containing a lectin domain
RNA
RNA (Transcript ID: NM_001204118.2)
C-type lectin domain containing 17A, transcript variant 1
m7G-5')ppp(5'-AGACGCCUGAGUCGGAGAGACAGGGGGCAGAGGUUGCCAAGCCCUGGCUGCCACUUGUCAGGUUCCCUGUGCUAGACAUGCAUAAUCUGUAUUCCAUCACUGGGUACCCGGACCCACCAGGGACCAUGGAGGAGGAGGAGGAGGAUGAUGACUAUGAGAACUCAACACCUCCCUACAAGGACCUUCCUCCCAAGCCAGGGACCAUGGAGGAGGAGGAGGAGGAUGAUGACUAUGAGAACUCAACACCUCCCUACAAGGACCUUCCUCCCAAGCCAGGGACCAUGGAGGAGGAGGAGGAGGAUGAUGACUAUGAGAACUCAACACCUCCCUACAAGGACCUUCCUCCCAAGCCAGGUUCAAGUGCUCCACCAAGACCUCCAAGGGCAGCAAAGGAAACAGAGAAACCCCCACUUCCUUGCAAGCCCCGGAACAUGACAGGCCUGGACCUCGCCGCUGUCACCUGUCCACCUCCUCAACUGGCUGUGAAUCUUGAGCCUUCUCCAUUGCAGCCAUCCCUGGCCGCAACUCCAGUCCCCUGGCUCAAUCAGAGGUCUGGAGGUCCUGGCUGCUGCCAGAAGAGGUGGAUGGUGUACCUGUGUCUGCUGGUGGUGACUUCCCUGUUCCUGGGCUGCCUUGGUCUCACUGUGACCCUGAUUAAGUACCAGGAGUUGAUGGAAGAACUGAGAAUGUUAAGCUUUCAGCAGAUGACGUGGCGAACAAAUAUGACUGGCAUGGCAGGGCUAGCUGGCCUGAAGCAUGACAUUGCCCGUGUAAGAGCUGACACCAACCAGUCCCUGGUGGAACUUUGGGGCUUAUUAGACUGCCGCCGAAUUACCUGUCCUGAAGGCUGGCUGCCCUUUGAGGGCAAGUGUUACUACUUCUCCCCAAGCACCAAGUCAUGGGAUGAGGCCCGGAUGUUCUGCCAGGAGAAUUACUCUCACUUGGUCAUCAUCAAUAGCUUUGCUGAGCACAAUUUUGUGGCCAAGGCCCAUGGCUCUCCACGGGUGUACUGGCUGGGGCUGAAUGACAGGGCCCAGGAAGGGGACUGGAGGUGGCUGGAUGGGUCUCCUGUGACAUUAAGCUUCUGGGAGCCAGAGGAACCCAAUAACAUCCACGAUGAGGACUGUGCUACCAUGAACAAAGGUGGCACCUGGAAUGAUCUCUCUUGCUACAAAACUACGUAUUGGAUUUGUGAGCGGAAAUGUUCCUGUUGAAGCCCAGGGCCGAGGCUGGGGGUCCAUAUCUGAGUGUCUCUUUGAGAUGAGAAUCUCCUGCCCUUUCGUGGACGGCCUUGCCUCUUCGUGAGUGGACACACAGAUGUGCCUCAAACAGGAUUGGCACCCUGGAUGCAGCAAGUUCCCAGGGGUGCAAGUCAGGCUGUUUCUAGAGUGAGGACUUGGGCUUGCCCUAGUAGAUGGUGAGCUGGGAGGAUGCUCAGAGCUUGGUGGUGGGAGGUCUCCCACUUCUGGGGUUGAAAGGAUCUUCACUAAGUUCCUGAUCAUGACUCUUGGGAAGUGAUACUAGCCCUGAGGACCCUGGGGCUGGUGUUGAACCUGGGAUGAAAUAUCCUGGCGCCUGUGAACCACAAAGAGCUGGGACUGGGCUCCUUUUCCUGCAGCCUCAAACUUCUGGGCUCAGGUGAUCCUCCCAUCUCAGCCUCCUGAGUAGCUGGGACUACACAUGCGCACCACCAUGCCUGGCCAAUUUUUUGUAGCAUUUAAAGAGAGGGAGUCUCACUAUGUUGCCCAGGCCAGUCUCAAACUCCUUGCCUCAAUGGAUCCUCCUACUUGGGCUUCCCAAAUUGUGAGGAUUACAGGUGUGAGCCACUGUGCCUGGCUCAAAAUUAUUAUUAUUAUUUUUAUAGAGAUGAGGUCUCACUCUGUUGCCGAGGCUGGUCUCAAACUCCUGGGGUCAAGCAAUCCUUCCGUGAUGGCCUCCCAAAGUGCUGGGAUUACAGGCAUGUGUCACCGUACCUGGCCGAUAUUUUUAUUUUUAUUUUUACUUUCCCCAUCUUUUCCUUUUUUUUUUUUUUCCAAACAAAAGCUUUGAAAGUGGUGACAGAAAAAUUUCCCUUUGAGCUAGACCUCUAGAUCUGCCUCGCACAGAAAUACAUUAAGUGGGCUGGUCUCAUGUAGUCCCCACAUCAUUGCAAAUUACAAACCUAAAAAUACAGAACAUCAGCGGAGAAGACAGGAGAGCUUCUAUAUUCACCCCAUGUCGUCCUCUCCAGACACUGCUUCCUUCCUGGUCUCAAACAGCACAAAUAACCCAGAAACCAUCAAAAUUAUUUUUGACCAGCAACUUUCUCAAUGUCUUGGGUGAGGUUUGCACAAGCUAAGUGGCAGAAUCAGACUUUUGCCAGAAGACUUGGCCCGUGGAACUUCUAUCCUUUUUUUUUUUUUUUUUUUUUUUUGAGAUAGGGUUUCAUUCUACUACCCAGGCUGGAGUGCAGUGGCACAAUCAUAGCUUACUGCACCCUCUGCCUCCUGGGCUCGAGUGAUCCUCCUGCCUCAGCCUCCCAAGUAGCUGGGACUACAGGCGUUCACCCUCACACCUGGCUGGCCCAUGGAACUUCUAGAAAGGCAUACCAGCUGAAAAGCAAGACCCCUACAUAGUGUGGCCAGGCAGGCCAUAACCUGGUCAUAUCCACACAGGACAACGAUGGACCUAUCUGCCAGCACGUGCCCUUGAGCUAUCUGUGGGUUGUAACGUCUUUGAUGAUAUAAUUCACUUUACUUGCCAGGCACAGUGGCUCACGCCUGUAAUCCCAGCACUCUGGGAGACUGAGGUGGGCUGAUCACCUGGGGUCAGGAUUUCGAGACCAGCCUGGCCAACAUGGUAAAAUCCUAUCUCUACUAAAAAUACAAAAAAAUUAGCUGGGCGUGGUGGCAUGUGCCUGUAAUCCCAGCUACUCAGGAGACUAAGGCACGAGAAUUGCUUGAACCCAGGAGGCGGAGGUUGCAGUGAGCCGAGAUUGUGCCACUGCACUCCAGCCUGGGUGACAGAGCAAGACUCCAUCUCAAAUAAAUAAAUAAAAAUAAAAAUUCACUUUA-3'- Poly-A tail
- Coding region
DNA
DNA (Gene ID: 388512)
C-type lectin domain containing 17A
strand +
NCBI CDS gene sequence (1137 bp)
5'-ATGCATAATCTGTATTCCATCACTGGGTACCCGGACCCACCAGGGACCATGGAGGAGGAGGAGGAGGATGATGACTATGAGAACTCAACACCTCCCTACAAGGACCTTCCTCCCAAGCCAGGGACCATGGAGGAGGAGGAGGAGGATGATGACTATGAGAACTCAACACCTCCCTACAAGGACCTTCCTCCCAAGCCAGGGACCATGGAGGAGGAGGAGGAGGATGATGACTATGAGAACTCAACACCTCCCTACAAGGACCTTCCTCCCAAGCCAGGTTCAAGTGCTCCACCAAGACCTCCAAGGGCAGCAAAGGAAACAGAGAAACCCCCACTTCCTTGCAAGCCCCGGAACATGACAGGCCTGGACCTCGCCGCTGTCACCTGTCCACCTCCTCAACTGGCTGTGAATCTTGAGCCTTCTCCATTGCAGCCATCCCTGGCCGCAACTCCAGTCCCCTGGCTCAATCAGAGGTCTGGAGGTCCTGGCTGCTGCCAGAAGAGGTGGATGGTGTACCTGTGTCTGCTGGTGGTGACTTCCCTGTTCCTGGGCTGCCTTGGTCTCACTGTGACCCTGATTAAGTACCAGGAGTTGATGGAAGAACTGAGAATGTTAAGCTTTCAGCAGATGACGTGGCGAACAAATATGACTGGCATGGCAGGGCTAGCTGGCCTGAAGCATGACATTGCCCGTGTAAGAGCTGACACCAACCAGTCCCTGGTGGAACTTTGGGGCTTATTAGACTGCCGCCGAATTACCTGTCCTGAAGGCTGGCTGCCCTTTGAGGGCAAGTGTTACTACTTCTCCCCAAGCACCAAGTCATGGGATGAGGCCCGGATGTTCTGCCAGGAGAATTACTCTCACTTGGTCATCATCAATAGCTTTGCTGAGCACAATTTTGTGGCCAAGGCCCATGGCTCTCCACGGGTGTACTGGCTGGGGCTGAATGACAGGGCCCAGGAAGGGGACTGGAGGTGGCTGGATGGGTCTCCTGTGACATTAAGCTTCTGGGAGCCAGAGGAACCCAATAACATCCACGATGAGGACTGTGCTACCATGAACAAAGGTGGCACCTGGAATGATCTCTCTTGCTACAAAACTACGTATTGGATTTGTGAGCGGAAATGTTCCTGTTGA-3'
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