Protein
Protein (NP_001177370)
Galectin 16
Galectin-16
LGALS16
galectin 16
Undefined
Low evidence
galectin-like
S-Type Lectins - Prototypical
b-sandwich / ConA-like
Only for mutated forms
NP_001177370
148003
A8MUM7
ENSP00000375904.2
A8MUM7
0.389
10.1016/j.bbagen.2020.129755
neXtProt, PFAM, InterPro
Protein sequence and protein families (fasta) (142 amino acids) Download
MSFLTVPYKLPVSLSVGSCVIIKGTLIDSSINEPQLQVDFYTEMNEDSEIAFHLRVHLGRRVVMNSREFGIWMLEENLHYVPFEDGKPFDLRIYVCHNEYEVKVNGEYIYAFVHRIPPSYVKMIQVWRDVSLDSVLVNNGRR
Mol* PDB structure viewerUniLectin3D
Structural models
AlphaFold v2: AF-A8MUM7-F1Download
  Model Confidence:
  •    Very high (pLDDT > 90)
  •    Confident (90 > pLDDT > 70)
  •    Low (70 > pLDDT > 50)
  •    Very low (pLDDT < 50)

  AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Ligand
Glycan ligands from structural data
bGal14Glc
Gal(b1-4)Glc
6LJQ, 6LJR
6LJQ, 6LJR
GlyConnect Structures
Expression
Human Protein Atlas
GeneCards
mRNA expression in normal human tissues for LGALS16 Gene
References
NCBI References (2 PubMed Identifiers)
  • Human galectin-16 has a pseudo ligand binding site and plays a role in regulating c-Rel-mediated lymphocyte activity. [33011338]
  • A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death. [19497882]
UniProt Main References (1 PubMed Identifiers)
  • The DNA sequence and biology of human chromosome 19. [15057824]
RNA
RNA (Transcript ID: NM_001190441.3)
NM_001190441.3
galectin 16
All isoforms of LGALS16 containing a lectin domain
ENST00000392051.4
50..478 (or 39655962.. 39660520)
39655913.. 39660647
NCBI Matured mRNA sequence 605 NTPDownload 
m7G-5')ppp(5'-ACUCAGAAGACUGGACACAAUUCCGAAGGUCGCCCAGAAGGAGAGGACAAUGUCAUUUCUAACUGUGCCAUACAAACUGCCUGUGUCUUUGUCUGUUGGUUCCUGCGUGAUAAUCAAAGGGACACUGAUCGACUCUUCUAUCAACGAACCACAGCUGCAGGUGGAUUUCUACACUGAGAUGAAUGAGGACUCAGAAAUUGCCUUCCAUUUGCGAGUGCACUUAGGCCGUCGUGUGGUCAUGAACAGUCGUGAGUUUGGGAUAUGGAUGUUGGAGGAGAAUUUACACUAUGUGCCCUUUGAGGAUGGCAAACCAUUUGACUUGCGCAUCUACGUGUGUCACAAUGAGUAUGAGGUAAAGGUAAAUGGUGAAUACAUUUAUGCCUUUGUCCAUCGAAUCCCGCCAUCAUAUGUGAAGAUGAUUCAAGUGUGGAGAGAUGUCUCCCUGGACUCAGUGCUUGUCAACAAUGGACGGAGAUGAUCACACUCCUCAUUGUUGAGGAAACCCUCUUUCUACCUGACCAUGGGAUUCCUAGAGCCUGCUAACAGAAUAAUCCCUCCUCAACCCCUUCCCCUACACUUGGUCAUUAAAACAGCACCAAACCGUA-3'- Poly-A tail
  • Coding region
NCBI Matured mRNA sequence viewer
;
More about the NCBI sViewer.
DNA
DNA (Gene ID: 148003)
LGALS16
galectin 16
NC_000019.10
19  39655962.. 39660520
39655962.. 39660520
strand +
CCDS54267.1
ClinVar, dbVar
ENSG00000249861
uc021uun.2
INSDC:
40039
OTTHUMG00000183083
ENA, DDBJ, Monarch
NCBI CDS Gene viewer
More about the NCBI sViewer.
NCBI CDS gene sequence (429 bp)
5'-ATGTCATTTCTAACTGTGCCATACAAACTGCCTGTGTCTTTGTCTGTTGGTTCCTGCGTGATAATCAAAGGGACACTGATCGACTCTTCTATCAACGAACCACAGCTGCAGGTGGATTTCTACACTGAGATGAATGAGGACTCAGAAATTGCCTTCCATTTGCGAGTGCACTTAGGCCGTCGTGTGGTCATGAACAGTCGTGAGTTTGGGATATGGATGTTGGAGGAGAATTTACACTATGTGCCCTTTGAGGATGGCAAACCATTTGACTTGCGCATCTACGTGTGTCACAATGAGTATGAGGTAAAGGTAAATGGTGAATACATTTATGCCTTTGTCCATCGAATCCCGCCATCATATGTGAAGATGATTCAAGTGTGGAGAGATGTCTCCCTGGACTCAGTGCTTGTCAACAATGGACGGAGATGA-3'
NCBI CDS gene sequence with introns (location: 39655962.. 39660520) (4559 bp)Download
NCBI Gene Viewer (CDS + introns)
NCBI CDS gene sequence with introns, 5'UTR and 3'UTR (location: 39655913.. 39660647) (4735 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions)
NCBI gene sequence (location: [39655913 - 1000].. 39660647) (5735 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions + 1000 dNTP to potentially reach the promotor)
Cite How to cite