NCBI Summary
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015].
Protein
Protein (NP_000867)
CI-MPR - Cation-independent mannose-6-phosphate receptor
Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222)
IGF2R
insulin like growth factor 2 receptor
Curated
P-type lectin
P-Type Lectins
b-barrel
MGAAAGRSPHLGPAPARRPQRSLLLLQLLLLVAAPGSTQAQAAPFPELCSYTWEAVDTKNNVLYKINICGSVDIVQCGPSSAVCMHDLKTRTYHSVGDSVLRSATRSLLEFNTTVSCDQQGTNHRVQSSIAFLCGKTLGTPEFVTATECVHYFEWRTTAACKKDIFKANKEVPCYVFDEELRKHDLNPLIKLSGAYLVDDSDPDTSLFINVCRDIDTLRDPGSQLRACPPGTAACLVRGHQAFDVGQPRDGLKLVRKDRLVLSYVREEAGKLDFCDGHSPAVTITFVCPSERREGTIPKLTAKSNCRYEIEWITEYACHRDYLESKTCSLSGEQQDVSIDLTPLAQSGGSSYISDGKEYLFYLNVCGETEIQFCNKKQAAVCQVKKSDTSQVKAAGRYHNQTLRYSDGDLTLIYFGGDECSSGFQRMSVINFECNKTAGNDGKGTPVFTGEVDCTYFFTWDTEYACVKEKEDLLCGATDGKKRYDLSALVRHAEPEQNWEAVDGSQTETEKKHFFINICHRVLQEGKARGCPEDAAVCAVDKNGSKNLGKFISSPMKEKGNIQLSYSDGDDCGHGKKIKTNITLVCKPGDLESAPVLRTSGEGGCFYEFEWHTAAACVLSKTEGENCTVFDSQAGFSFDLSPLTKKNGAYKVETKKYDFYINVCGPVSVSPCQPDSGACQVAKSDEKTWNLGLSNAKLSYYDGMIQLNYRGGTPYNNERHTPRATLITFLCDRDAGVGFPEYQEEDNSTYNFRWYTSYACPEEPLECVVTDPSTLEQYDLSSLAKSEGGLGGNWYAMDNSGEHVTWRKYYINVCRPLNPVPGCNRYASACQMKYEKDQGSFTEVVSISNLGMAKTGPVVEDSGSLLLEYVNGSACTTSDGRQTTYTTRIHLVCSRGRLNSHPIFSLNWECVVSFLWNTEAACPIQTTTDTDQACSIRDPNSGFVFNLNPLNSSQGYNVSGIGKIFMFNVCGTMPVCGTILGKPASGCEAETQTEELKNWKPARPVGIEKSLQLSTEGFITLTYKGPLSAKGTADAFIVRFVCNDDVYSGPLKFLHQDIDSGQGIRNTYFEFETALACVPSPVDCQVTDLAGNEYDLTGLSTVRKPWTAVDTSVDGRKRTFYLSVCNPLPYIPGCQGSAVGSCLVSEGNSWNLGVVQMSPQAAANGSLSIMYVNGDKCGNQRFSTRITFECAQISGSPAFQLQDGCEYVFIWRTVEACPVVRVEGDNCEVKDPRHGNLYDLKPLGLNDTIVSAGEYTYYFRVCGKLSSDVCPTSDKSKVVSSCQEKREPQGFHKVAGLLTQKLTYENGLLKMNFTGGDTCHKVYQRSTAIFFYCDRGTQRPVFLKETSDCSYLFEWRTQYACPPFDLTECSFKDGAGNSFDLSSLSRYSDNWEAITGTGDPEHYLINVCKSLAPQAGTEPCPPEAAACLLGGSKPVNLGRVRDGPQWRDGIIVLKYVDGDLCPDGIRKKSTTIRFTCSESQVNSRPMFISAVEDCEYTFAWPTATACPMKSNEHDDCQVTNPSTGHLFDLSSLSGRAGFTAAYSEKGLVYMSICGENENCPPGVGACFGQTRISVGKANKRLRYVDQVLQLVYKDGSPCPSKSGLSYKSVISFVCRPEARPTNRPMLISLDKQTCTLFFSWHTPLACEQATECSVRNGSSIVDLSPLIHRTGGYEAYDESEDDASDTNPDFYINICQPLNPMHGVPCPAGAAVCKVPIDGPPIDIGRVAGPPILNPIANEIYLNFESSTPCLADKHFNYTSLIAFHCKRGVSMGTPKLLRTSECDFVFEWETPVVCPDEVRMDGCTLTDEQLLYSFNLSSLSTSTFKVTRDSRTYSVGVCTFAVGPEQGGCKDGGVCLLSGTKGASFGRLQSMKLDYRHQDEAVVLSYVNGDRCPPETDDGVPCVFPFIFNGKSYEECIIESRAKLWCSTTADYDRDHEWGFCRHSNSYRTSSIIFKCDEDEDIGRPQVFSEVRGCDVTFEWKTKVVCPPKKLECKFVQKHKTYDLRLLSSLTGSWSLVHNGVSYYINLCQKIYKGPLGCSERASICRRTTTGDVQVLGLVHTQKLGVIGDKVVVTYSKGYPCGGNKTASSVIELTCTKTVGRPAFKRFDIDSCTYYFSWDSRAACAVKPQEVQMVNGTITNPINGKSFSLGDIYFKLFRASGDMRTNGDNYLYEIQLSSITSSRNPACSGANICQVKPNDQHFSRKVGTSDKTKYYLQDGDLDVVFASSSKCGKDKTKSVSSTIFFHCDPLVEDGIPEFSHETADCQYLFSWYTSAVCPLGVGFDSENPGDDGQMHKGLSERSQAVGAVLSLLLVALTCCLLALLLYKKERRETVISKLTTCCRRSSNVSYKYSKVNKEEETDENETEWLMEEIQLPPPRQGKEGQENGHITTKSVKALSSLHGDDQDSEDEVLTIPEVKVHSGRGAGAESSHPVRNAQSNALQEREDDRVGLVRGEKARKGKSSSAQQKTVSSTKLVSFHDDSDEDLLHI
Mol* PDB structure viewerUniLectin3D
Ligand
Glycan ligands from structural data
aMan13aMan16(aMan13)bMan14bGlcNAc14GlcNAc
Man(a1-3)Man(a1-6)[Man(a1-3)]Man(b1-4)GlcNAc(b1-4)GlcNAc
aMan12aMan12aMan13bMan14bGlcNAc14bGlcNAc
Man(a1-2)Man(a1-2)Man(a1-3)Man(b1-4)GlcNAc(b1-4)GlcNAc
References
NCBI References (10 PubMed Identifiers)
- IGF IIRalpha-triggered pathological manifestations in the heart aggravate renal inflammation in STZ-induced type-I diabetes rats. [34233296]
- The role of insulin-like growth factor in Acrochordon Etiopathology. [33143702]
- Promoter-restricted histone code, not the differentially methylated DNA regions or antisense transcripts, marks the imprinting status of IGF2R in human and mouse. [15294879]
- M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity. [7493029]
- Functional polymorphism in the parental imprinting of the human IGF2R gene. [8267611]
- Human insulin-like growth factor type I and type II receptors are not imprinted. [8111387]
- The insulin-like growth factor type-2 receptor gene is imprinted in the mouse but not in humans. [8220428]
- Expression of insulin-like growth factors I and II and their receptor mRNAs in primary human astrocytomas and meningiomas. in vivo studies using in situ hybridization and immunocytochemistry. [1370435]
- The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells. [2963003]
- Insulin-like growth factor II receptor as a multifunctional binding protein. [2957598]
UniProt Main References (25 PubMed Identifiers)
- Genomic structure of the human M6P/IGF2 receptor. [9892739]
- The DNA sequence and analysis of human chromosome 6. [14574404]
- Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptor contributes to T cell activation. [10900005]
- Sorting of mannose 6-phosphate receptors mediated by the GGAs. [11387475]
- Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. [12754519]
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. [17081983]
- Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line. [17487921]
- Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. [18220336]
- Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment. [19367720]
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. [18691976] Show more
RNA
RNA (Transcript ID: NM_000876.4)
m7G-5')ppp(5'-GCCGCUGUCGCUGUCGCCGAGCCCAGUCGAGCCGCGCUCACCUCGGGCUCCCGCUCCGUCUCCACCUCCGCCUUUGCCCUGGCGGCGCGACCCCGUCCCGGGCGCGGCCCCCAGCAGUCGCGCGCCGUUAGCCUCGCGCCCGCCGCGCAGUCCGGGCCCGGCGCGAUGGGGGCCGCCGCCGGCCGGAGCCCCCACCUGGGGCCCGCGCCCGCCCGCCGCCCGCAGCGCUCUCUGCUCCUGCUGCAGCUGCUGCUGCUCGUCGCUGCCCCGGGGUCCACGCAGGCCCAGGCCGCCCCGUUCCCCGAGCUGUGCAGUUAUACAUGGGAAGCUGUUGAUACCAAAAAUAAUGUACUUUAUAAAAUCAACAUCUGUGGAAGUGUGGAUAUUGUCCAGUGCGGGCCAUCAAGUGCUGUUUGUAUGCACGACUUGAAGACACGCACUUAUCAUUCAGUGGGUGACUCUGUUUUGAGAAGUGCAACCAGAUCUCUCCUGGAAUUCAACACAACAGUGAGCUGUGACCAGCAAGGCACAAAUCACAGAGUCCAGAGCAGCAUUGCCUUCCUGUGUGGGAAAACCCUGGGAACUCCUGAAUUUGUAACUGCAACAGAAUGUGUGCACUACUUUGAGUGGAGGACCACUGCAGCCUGCAAGAAAGACAUAUUUAAAGCAAAUAAGGAGGUGCCAUGCUAUGUGUUUGAUGAAGAGUUGAGGAAGCAUGAUCUCAAUCCUCUGAUCAAGCUUAGUGGUGCCUACUUGGUGGAUGACUCCGAUCCGGACACUUCUCUAUUCAUCAAUGUUUGUAGAGACAUAGACACACUACGAGACCCAGGUUCACAGCUGCGGGCCUGUCCCCCCGGCACUGCCGCCUGCCUGGUAAGAGGACACCAGGCGUUUGAUGUUGGCCAGCCCCGGGACGGACUGAAGCUGGUGCGCAAGGACAGGCUUGUCCUGAGUUACGUGAGGGAAGAGGCAGGAAAGCUAGACUUUUGUGAUGGUCACAGCCCUGCGGUGACUAUUACAUUUGUUUGCCCGUCGGAGCGGAGAGAGGGCACCAUUCCCAAACUCACAGCUAAAUCCAACUGCCGCUAUGAAAUUGAGUGGAUUACUGAGUAUGCCUGCCACAGAGAUUACCUGGAAAGUAAAACUUGUUCUCUGAGCGGCGAGCAGCAGGAUGUCUCCAUAGACCUCACACCACUUGCCCAGAGCGGAGGUUCAUCCUAUAUUUCAGAUGGAAAAGAAUAUUUGUUUUAUUUGAAUGUCUGUGGAGAAACUGAAAUACAGUUCUGUAAUAAAAAACAAGCUGCAGUUUGCCAAGUGAAAAAGAGCGAUACCUCUCAAGUCAAAGCAGCAGGAAGAUACCACAAUCAGACCCUCCGAUAUUCGGAUGGAGACCUCACCUUGAUAUAUUUUGGAGGUGAUGAAUGCAGCUCAGGGUUUCAGCGGAUGAGCGUCAUAAACUUUGAGUGCAAUAAAACCGCAGGUAACGAUGGGAAAGGAACUCCUGUAUUCACAGGGGAGGUUGACUGCACCUACUUCUUCACAUGGGACACGGAAUACGCCUGUGUUAAGGAGAAGGAAGACCUCCUCUGCGGUGCCACCGACGGGAAGAAGCGCUAUGACCUGUCCGCGCUGGUCCGCCAUGCAGAACCAGAGCAGAAUUGGGAAGCUGUGGAUGGCAGUCAGACGGAAACAGAGAAGAAGCAUUUUUUCAUUAAUAUUUGUCACAGAGUGCUGCAGGAAGGCAAGGCACGAGGGUGUCCCGAGGACGCGGCAGUGUGUGCAGUGGAUAAAAAUGGAAGUAAAAAUCUGGGAAAAUUUAUUUCCUCUCCCAUGAAAGAGAAAGGAAACAUUCAACUCUCUUAUUCAGAUGGUGAUGAUUGUGGUCAUGGCAAGAAAAUUAAAACUAAUAUCACACUUGUAUGCAAGCCAGGUGAUCUGGAAAGUGCACCAGUGUUGAGAACUUCUGGGGAAGGCGGUUGCUUUUAUGAGUUUGAGUGGCACACAGCUGCGGCCUGUGUGCUGUCUAAGACAGAAGGGGAGAACUGCACGGUCUUUGACUCCCAGGCAGGGUUUUCUUUUGACUUAUCACCUCUCACAAAGAAAAAUGGUGCCUAUAAAGUUGAGACAAAGAAGUAUGACUUUUAUAUAAAUGUGUGUGGCCCGGUGUCUGUGAGCCCCUGUCAGCCAGACUCAGGAGCCUGCCAGGUGGCAAAAAGUGAUGAGAAGACUUGGAACUUGGGUCUGAGUAAUGCGAAGCUUUCAUAUUAUGAUGGGAUGAUCCAACUGAACUACAGAGGCGGCACACCCUAUAACAAUGAAAGACACACACCGAGAGCUACGCUCAUCACCUUUCUCUGUGAUCGAGACGCGGGAGUGGGCUUCCCUGAAUAUCAGGAAGAGGAUAACUCCACCUACAACUUCCGGUGGUACACCAGCUAUGCCUGCCCGGAGGAGCCCCUGGAAUGCGUAGUGACCGACCCCUCCACGCUGGAGCAGUACGACCUCUCCAGUCUGGCAAAAUCUGAAGGUGGCCUUGGAGGAAACUGGUAUGCCAUGGACAACUCAGGGGAACAUGUCACGUGGAGGAAAUACUACAUUAACGUGUGUCGGCCUCUGAAUCCAGUGCCGGGCUGCAACCGAUAUGCAUCGGCUUGCCAGAUGAAGUAUGAAAAAGAUCAGGGCUCCUUCACUGAAGUGGUUUCCAUCAGUAACUUGGGAAUGGCAAAGACCGGCCCGGUGGUUGAGGACAGCGGCAGCCUCCUUCUGGAAUACGUGAAUGGGUCGGCCUGCACCACCAGCGAUGGCAGACAGACCACAUAUACCACGAGGAUCCAUCUCGUCUGCUCCAGGGGCAGGCUGAACAGCCACCCCAUCUUUUCUCUCAACUGGGAGUGUGUGGUCAGUUUCCUGUGGAACACAGAGGCUGCCUGUCCCAUUCAGACAACGACGGAUACAGACCAGGCUUGCUCUAUAAGGGAUCCCAACAGUGGAUUUGUGUUUAAUCUUAAUCCGCUAAACAGUUCGCAAGGAUAUAACGUCUCUGGCAUUGGGAAGAUUUUUAUGUUUAAUGUCUGCGGCACAAUGCCUGUCUGUGGGACCAUCCUGGGAAAACCUGCUUCUGGCUGUGAGGCAGAAACCCAAACUGAAGAGCUCAAGAAUUGGAAGCCAGCAAGGCCAGUCGGAAUUGAGAAAAGCCUCCAGCUGUCCACAGAGGGCUUCAUCACUCUGACCUACAAAGGGCCUCUCUCUGCCAAAGGUACCGCUGAUGCUUUUAUCGUCCGCUUUGUUUGCAAUGAUGAUGUUUACUCAGGGCCCCUCAAAUUCCUGCAUCAAGAUAUCGACUCUGGGCAAGGGAUCCGAAACACUUACUUUGAGUUUGAAACCGCGUUGGCCUGUGUUCCUUCUCCAGUGGACUGCCAAGUCACCGACCUGGCUGGAAAUGAGUACGACCUGACUGGCCUAAGCACAGUCAGGAAACCUUGGACGGCUGUUGACACCUCUGUCGAUGGGAGAAAGAGGACUUUCUAUUUGAGCGUUUGCAAUCCUCUCCCUUACAUUCCUGGAUGCCAGGGCAGCGCAGUGGGGUCUUGCUUAGUGUCAGAAGGCAAUAGCUGGAAUCUGGGUGUGGUGCAGAUGAGUCCCCAAGCCGCGGCGAAUGGAUCUUUGAGCAUCAUGUAUGUCAACGGUGACAAGUGUGGGAACCAGCGCUUCUCCACCAGGAUCACGUUUGAGUGUGCUCAGAUAUCGGGCUCACCAGCAUUUCAGCUUCAGGAUGGUUGUGAGUACGUGUUUAUCUGGAGAACUGUGGAAGCCUGUCCCGUUGUCAGAGUGGAAGGGGACAACUGUGAGGUGAAAGACCCAAGGCAUGGCAACUUGUAUGACCUGAAGCCCCUGGGCCUCAACGACACCAUCGUGAGCGCUGGCGAAUACACUUAUUACUUCCGGGUCUGUGGGAAGCUUUCCUCAGACGUCUGCCCCACAAGUGACAAGUCCAAGGUGGUCUCCUCAUGUCAGGAAAAGCGGGAACCGCAGGGAUUUCACAAAGUGGCAGGUCUCCUGACUCAGAAGCUAACUUAUGAAAAUGGCUUGUUAAAAAUGAACUUCACGGGGGGGGACACUUGCCAUAAGGUUUAUCAGCGCUCCACAGCCAUCUUCUUCUACUGUGACCGCGGCACCCAGCGGCCAGUAUUUCUAAAGGAGACUUCAGAUUGUUCCUACUUGUUUGAGUGGCGAACGCAGUAUGCCUGCCCACCUUUCGAUCUGACUGAAUGUUCAUUCAAAGAUGGGGCUGGCAACUCCUUCGACCUCUCGUCCCUGUCAAGGUACAGUGACAACUGGGAAGCCAUCACUGGGACGGGGGACCCGGAGCACUACCUCAUCAAUGUCUGCAAGUCUCUGGCCCCGCAGGCUGGCACUGAGCCGUGCCCUCCAGAAGCAGCCGCGUGUCUGCUGGGUGGCUCCAAGCCCGUGAACCUCGGCAGGGUAAGGGACGGACCUCAGUGGAGAGAUGGCAUAAUUGUCCUGAAAUACGUUGAUGGCGACUUAUGUCCAGAUGGGAUUCGGAAAAAGUCAACCACCAUCCGAUUCACCUGCAGCGAGAGCCAAGUGAACUCCAGGCCCAUGUUCAUCAGCGCCGUGGAGGACUGUGAGUACACCUUUGCCUGGCCCACAGCCACAGCCUGUCCCAUGAAGAGCAACGAGCAUGAUGACUGCCAGGUCACCAACCCAAGCACAGGACACCUGUUUGAUCUGAGCUCCUUAAGUGGCAGGGCGGGAUUCACAGCUGCUUACAGCGAGAAGGGGUUGGUUUACAUGAGCAUCUGUGGGGAGAAUGAAAACUGCCCUCCUGGCGUGGGGGCCUGCUUUGGACAGACCAGGAUUAGCGUGGGCAAGGCCAACAAGAGGCUGAGAUACGUGGACCAGGUCCUGCAGCUGGUGUACAAGGAUGGGUCCCCUUGUCCCUCCAAAUCCGGCCUGAGCUAUAAGAGUGUGAUCAGUUUCGUGUGCAGGCCUGAGGCCAGGCCAACCAAUAGGCCCAUGCUCAUCUCCCUGGACAAGCAGACAUGCACUCUCUUCUUCUCCUGGCACACGCCGCUGGCCUGCGAGCAAGCGACCGAAUGUUCCGUGAGGAAUGGAAGCUCUAUUGUUGACUUGUCUCCCCUUAUUCAUCGCACUGGUGGUUAUGAGGCUUAUGAUGAGAGUGAGGAUGAUGCCUCCGAUACCAACCCUGAUUUCUACAUCAAUAUUUGUCAGCCACUAAAUCCCAUGCACGGAGUGCCCUGUCCUGCCGGAGCCGCUGUGUGCAAAGUUCCUAUUGAUGGUCCCCCCAUAGAUAUCGGCCGGGUAGCAGGACCACCAAUACUCAAUCCAAUAGCAAAUGAGAUUUACUUGAAUUUUGAAAGCAGUACUCCUUGCUUAGCGGACAAGCAUUUCAACUACACCUCGCUCAUCGCGUUUCACUGUAAGAGAGGUGUGAGCAUGGGAACGCCUAAGCUGUUAAGGACCAGCGAGUGCGACUUUGUGUUCGAAUGGGAGACUCCUGUCGUCUGUCCUGAUGAAGUGAGGAUGGAUGGCUGUACCCUGACAGAUGAGCAGCUCCUCUACAGCUUCAACUUGUCCAGCCUUUCCACGAGCACCUUUAAGGUGACUCGCGACUCGCGCACCUACAGCGUUGGGGUGUGCACCUUUGCAGUCGGGCCAGAACAAGGAGGCUGUAAGGACGGAGGAGUCUGUCUGCUCUCAGGCACCAAGGGGGCAUCCUUUGGACGGCUGCAAUCAAUGAAACUGGAUUACAGGCACCAGGAUGAAGCGGUCGUUUUAAGUUACGUGAAUGGUGAUCGUUGCCCUCCAGAAACCGAUGACGGCGUCCCCUGUGUCUUCCCCUUCAUAUUCAAUGGGAAGAGCUACGAGGAGUGCAUCAUAGAGAGCAGGGCGAAGCUGUGGUGUAGCACAACUGCGGACUACGACAGAGACCACGAGUGGGGCUUCUGCAGACACUCAAACAGCUACCGGACAUCCAGCAUCAUAUUUAAGUGUGAUGAAGAUGAGGACAUUGGGAGGCCACAAGUCUUCAGUGAAGUGCGUGGGUGUGAUGUGACAUUUGAGUGGAAAACAAAAGUUGUCUGCCCUCCAAAGAAGUUGGAGUGCAAAUUCGUCCAGAAACACAAAACCUACGACCUGCGGCUGCUCUCCUCUCUCACCGGGUCCUGGUCCCUCGUCCACAACGGAGUCUCGUACUAUAUAAAUCUGUGCCAGAAAAUAUAUAAAGGGCCCCUGGGCUGCUCUGAAAGGGCCAGCAUUUGCAGAAGGACCACAACUGGUGACGUCCAGGUCCUGGGACUCGUUCACACGCAGAAGCUGGGUGUCAUAGGUGACAAAGUUGUUGUCACGUACUCCAAAGGUUAUCCGUGUGGUGGAAAUAAGACCGCAUCCUCCGUGAUAGAAUUGACCUGUACAAAGACGGUGGGCAGACCUGCAUUCAAGAGGUUUGAUAUCGACAGCUGCACUUACUACUUCAGCUGGGACUCCCGGGCUGCCUGCGCCGUGAAGCCUCAGGAGGUGCAGAUGGUGAAUGGGACCAUCACCAACCCUAUAAAUGGCAAGAGCUUCAGCCUCGGAGAUAUUUAUUUUAAGCUGUUCAGAGCCUCUGGGGACAUGAGGACCAAUGGGGACAACUACCUGUAUGAGAUCCAACUUUCCUCCAUCACAAGCUCCAGAAACCCGGCGUGCUCUGGAGCCAACAUAUGCCAGGUGAAGCCCAACGAUCAGCACUUCAGUCGGAAAGUUGGAACCUCUGACAAGACCAAGUACUACCUUCAAGACGGCGAUCUCGAUGUCGUGUUUGCCUCUUCCUCUAAGUGCGGAAAGGAUAAGACCAAGUCUGUUUCUUCCACCAUCUUCUUCCACUGUGACCCUCUGGUGGAGGACGGGAUCCCCGAGUUCAGUCACGAGACUGCCGACUGCCAGUACCUCUUCUCUUGGUACACCUCAGCCGUGUGUCCUCUGGGGGUGGGCUUUGACAGCGAGAAUCCCGGGGACGACGGGCAGAUGCACAAGGGGCUGUCAGAACGGAGCCAGGCAGUCGGCGCGGUGCUCAGCCUGCUGCUGGUGGCGCUCACCUGCUGCCUGCUGGCCCUGUUGCUCUACAAGAAGGAGAGGAGGGAAACAGUGAUAAGUAAGCUGACCACUUGCUGUAGGAGAAGUUCCAACGUGUCCUACAAAUACUCAAAGGUGAAUAAGGAAGAAGAGACAGAUGAGAAUGAAACAGAGUGGCUGAUGGAAGAGAUCCAGCUGCCUCCUCCACGGCAGGGAAAGGAAGGGCAGGAGAACGGCCAUAUUACCACCAAGUCAGUGAAAGCCCUCAGCUCCCUGCAUGGGGAUGACCAGGACAGUGAGGAUGAGGUUCUGACCAUCCCAGAGGUGAAAGUUCACUCGGGCAGGGGAGCUGGGGCAGAGAGCUCCCACCCAGUGAGAAACGCACAGAGCAAUGCCCUUCAGGAGCGUGAGGACGAUAGGGUGGGGCUGGUCAGGGGUGAGAAGGCGAGGAAAGGGAAGUCCAGCUCUGCACAGCAGAAGACAGUGAGCUCCACCAAGCUGGUGUCCUUCCAUGACGACAGCGACGAGGACCUCUUACACAUCUGACUCCGCAGUGCCUGCAGGGGAGCACGGAGCCGCGGGACAGCCAAGCACCUCCAACCAAAUAAGACUUCCACUCGAUGAUGCUUCUAUAAUUUUGCCUUUAACAGAAACUUUCAAAAGGGAAGAGUUUUUGUGAUGGGGGAGAGGGUGAAGGAGGUCAGGCCCCACUCCUUCCUGAUUGUUUACAGUCAUUGGAAUAAGGCAUGGCUCAGAUCGGCCACAGGGCGGUACCUUGUGCCCAGGGUUUUGCCCCAAGUCCUCAUUUAAAAGCAUAAGGCCGGACGCAUCUCAAAACAGAGGGCUGCAUUCGAAGAAACCCUUGCUGCUUUAGUCCCGAUAGGGUAUUUGACCCCGAUAUAUUUUAGCAUUUUAAUUCUCUCCCCCUAUUUAUUGACUUUGACAAUUACUCAGGUUUGAGAAAAAGGAAAAAAAAACAGCCACCGUUUCUUCCUGCCAGCAGGGGUGUGAUGUACCAGUUUGUCCAUCUUGAGAUGGUGAGGCUGUCAGUGUAUGGGGCAGCUUCCGGCGGGAUGUUGAACUGGUCAUUAAUGUGUCCCCUGAGUUGGAGCUCAUUCUGUCUCUUUUCUCUUUUGCUUUCUGUUUCUUAAGGGCACACACACGUGCGUGCGAGCACACACACACAUACGUGCACAGGGUCCCCGAGUGCCUAGGUUUUGGAGAGUUUGCCUGUUCUAUGCCUUUAGUCAGGAAUGGCUGCACCUUUUUGCAUGAUAUCUUCAAGCCUGGGCGUACAGAGCACAUUUGUCAGUAUUUUUGCCGGCUGGUGAAUUCAAACAACCUGCCCAAAGAUUGAUUUGUGUGUUUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGAGUGGAGUUGAGGUGUCAGAGAAAAUGAAUUUUUUCCAGAUUUGGGGUAUAGGUCUCAUCUCUUCAGGUUCUCAUGAUACCACCUUUACUGUGCUUAUUUUUUUAAGAAAAAAGUGUUGAUCAACCAUUCGACCUAUAAGAAGCCUUAAUUUGCACAGUGUGUGACUUACAGAAACUGCAUGAAAAAUCAUGGGCCAGAGCCUCGGCCCUAGCAUUGCACUUGGCCUCAUGCUGGAGGGAGGCUGGGCGGGUACAGCGCGGAGGAGGAGGGAGGCCAGGCGGGCAUGGCGUGGAGGAGGAGGGAGGCCGGGCGGUCACAGCAUGGAGGAGGAGGGAGGCGCUGCUGGUGUUCUUAUUCUGGCGGCAGCGCCUUUCCUGCCAUGUUUAGUGAAUGACUUUUCUCGCAUUGUAGAAUUGUAUAUAGACUCUGGUGUUCUAUUGCUGAGAAGCAAACCGCCCUGCAGCAUCCCUCAGCCUGUACCGGUUUGGCUGGCUUGUUUGAUUUCAACAUGAGUGUAUUUUUUAAAAUUGAUUUUUCUCUUCAUUUUUUUUUCAAUCAACUUUACUGUAAUAUAAAGUAUUCAACAAUUUCAAUAAAAGAUAAAUUAUUAAUUGGGUGUUACCAUUUUUUCCUUGAUAGUGAGACGUUCCCGAGCGAGUUACCCAUCUGCCUGCCUGUCUUUUCUUUCUGUUAAGUGACUGAAUUUGGGUUUUAACUCUGGUGUUCUCGUUGACCCUUUAUGAGGCAGCACUUUCAUUUUUCUCCAGAGUCUCCUGGUCGUAGGUGUUAACUUUGGGUCCAAUCUGCCUUCCCUUGGCUCUUUCUAGAUCCGAUUUCUUUACCUUCUCCAGGCCAACCUCGGGGUGUGGUCCUGUUCAUCAAAACAAUGAACAUGGAGUUUAGAGUCCAGUGAGUCAAUAAAGCUUUUUUUUGUGCAACCUGAUCUAACAUGGAGAUGUUUUCUCUUGAGUAAACUCACUGAGUUUUCCAUCUUAAAUUACUCAGCAGUGACUGAGAGCUACCUGCAUGGAAGCAGGAAGUUACUCCAGUGUUAUAAACAAACUUCUUAGACUCAACAUCCUAUUCUCCAUCCCUUUUUUUUUCCUGUAGAGUCCAAAAACCUCAACCGUCUCAUUUUUAAAUUAUCCAAUUGGAGUUACCUUUUUAAAAAAGUUAUUCUUAAGGACUUUCCAAUACCUCUCCUGAGGAAGACAUGUCAGGUCUUCUAAAAGUUUACAUUAUGACCAAAGAAAGAUGCUGGUCCUCAGGCAUUCUACCCAGGGGGCUGUUCUCCAGGCCAUUCCCACCUCCUGCUAAGACCAUGGGGAGCCCUCUCUGUAAGGAGGGGCAUAUGCAGGGACCUGCCCAUCCCCUUGGUAAGCUGGAUGGCAAAAAGGCAUGUUGUCUGCACCACUGGCUGCCUGCUAAUGUCGCUGUCAGUGGGGAAGGAGAAGUGACAACACGUUUGAGUGCAUUUGCUUUGACUCUUAGAAACCCAAGCCUCUGAAAAAAGAGUAACUACUUGCCAGCUGUUGUUACAGAUGAUAUUUUUAGGAAAACAUCCCGUGACAGCAAAUCAGAAUUGGACUCUUUUUCAGAGAAAUGAUUUUAUUGAUGGAGUACAACCUGGGUAUUUAGCUUCCUUUCAACAAAAUUUUUUGUGCCCCUUUCUUGAGACUGUCCAUGAAUGACAGAGACAUAGAAUAAGAACUGGGGUGCUAAAGAUGGAAUAGGCAAACCCCACACCAAGGAAAUCCACAGUGAAGUGGAAAUCUGGUUCUUAUGAACAUUUUAAGAGCAUCUGAAGCCUGUACUUCACCAACCCUAAAAUAAUACGUAACACGAGAUGAUUCCUCAGGAAGGAACAUAUAGACAUACAGACAGGAGACAACAUAUAGACAUUAGAACUUACAGGACAAAGAACUCUUUUUCCCUGAAUCAUUUGAGAUGAAGUUUCUUCCCAUCACCAGGCAUUCCUACAAACAAGGACCUUCACACGACUAAGAUGCCACCUGGUGAUUAAAGAACACUUUGGGCUGGUCCGAUCCAUUGUACAAGUUAAAGCACUGAUGGGUACACAGGUCUUACCCCUGUUGGCGAUCGGGUCACAAGGAGCCAGUGUGUGUGUCACCAGGAGGUUGUAUGGACGAGACUGGAUUUCUGGAAAUAUCCUUUACUGACUCUGAAGAAUCCCAUGGCUCAGGGAGGUACACUCAUGUCCUUUCUUACUUCUCCGGUUCCACUCUGUUGACUAGUAGUUGGCCUCUUGAGCCAUACUUGCUGUCAGUUCUGGACAUUGUUCUGUGAGAAUGGGGUCAACGGGCAGUCGUGGUGCAGGUGAGCUUGUGUGCAAGGCGGCAAGAUAGCCACAUUGAGUUGGGGACAGUAUGGCCUGGGGGUGUUGGAUAGGUAAGGCAGAAGCAAGCCCAGAACUUGGAGCCUGUUGUGACUGUCACAGUAAGGAGUUUGAAGUCCUGAAAGCAGUUGAGAGCUGUAGGAGGGCCAGAUUGGGCUUUUGAGCAAGAUAGUCUAGAUGAAAGUAAAGAGAUGGAGACGCUUCAGCAACCAGAUGGGAGGUUGGGCAUGGGAGCUGUGGCUGUGCUGAGCUGAGAAGCCUCAGACUGCCUGCGAGGCUCUCUCUGGGAGGAAGUCAGGUCUUUCUUUCCUUCGUUUCCUUCCUUUCAUUCCUUUCCUUUCCUUCCUUUUUCCUCUUUCUUUCUUUCCUUUUCUCUCUCUCUCUUUUUCUUUCUCUCUUUCUUUCGAGAUGGAGUCUCGCUCUGUUGCCAGGCUGGAGUGCAGUGGCAUGAUCUCGGCUCACUGCAAUCUCUGCCUCCCGGGUUCAAGGGAUUCUCCUGCCUCAGCCUCCCUAGUAGCUGGGAUUAAAGGCACGCACUGCCACGCCCGGCUAAUUUUUGUAUUUUUAAUAGCGACAGGGUUUCACCGUGUUGGCCAGGAUGGUCUCGAUCUCCUGACCUCAUGAUCCACCUGCCUCGGCCUCCGAAAGUGCUGGGAUUACAGGCGUGAGCCACCGUGCCCAGCCAGGUCUUUUUCUUAAAGAGGGACAGACUGAAGGUAGGCUGUGAAUGGUCAGUUAUUUGUAUUUCUUUACCUUUUAUGCUAUCUUGUAGUUUGACCAGUUUGCAAAACAAAUUGAAUAAAAAGUAAUUGAUAAUGUUGUUUUGAUGCUCAGUGUUUGAGGGAAACACAAUCUAGUGAAUGGGGUUAUUGGUUGUCACACCUGGGAGAGUGAAAAUGAGGGGCUCACAACCCAGGUGAGGUCAUCUGGUGCCACUCAGCCCCAUCCCAGAGAAAGCAGCCUUGGGAUGCUGGCCUCGGUGACAACCAAGAAGUGAUGGUGGGUUGCUAGAGACAGGGUGGAGCACAGAGCCCUGGAAGGAAGCAGGAAGUCAGGUUCAAGAAAGGACUUGUGACCUCACCCUUGGCUUCAGGGUUUUAUUUUUCUUUCUUUUAAAACAUUUUGAGACAACAUGUAGACAUUCAAACUUACAGAACAAAGAACUAUUUUUUCCCUGAAUCAUUUGAGACUAAGUUCCCUCCUAUCACCAGACAUUUCUACAAAUGAGGACCUUCACAGGACUAAGGUGCCACCAUCAGAACCACAAUAUGUGGGGACGGUACUGCCAGCUAAGCCUUAGUGCUGUUUCGGUGUUGACAGCUGUCACAAUGAUGCCCUUUUCAGUAGAGGAGCCUGUGAUGGUCACGUGUUGCAGGUGAUCAUUGUGCCAUUUGGUUUACUUCUGUCUGGAAAGUUUCUCCUUUCUGUAACCUCCAUGACCUUGACACAUGAGGUCACUCUUCUCACCCGCCCCACCUCUGGGAGGGUGCCUGAUUUGCCCUGCCCCACCCAGCGGCUUUAGGACUCAGCUCUUCAGGAACAAUUAGGGAGAGGGCCCUUGGGUCUAACUGCAAAAUCAUACUUGAACUAGAAAAUCCCGUUGGCAUAGGUAUGGAUUGUCAUAUAGAAACAUUUUUCGCAGUGUGCCCCGUGGAACACUUGUUCUGUAUGUUGUUAACAGAUGUUUUGCAAAAAAUGAAAAGGACCUGAGCUCUAAUAAGUUUGGGAAAUGCUGAAUUGAAGUGAAACAGCUUUUCUUGGUGUGAGACCUUUCAGAGUCUUUAAAGGAGAGUUGCUGACCACACGUGAAAUCACAAUAGAAAAUGGCCAGCAGGCCUCCAGGUAGGCAGCAAUUCCUAGACAUUUGCCUGUGUUCCCUGGGGGAGCUGGUGGCCUGUGACCAUCCACUGGGAAAUUCCCUUCUGUGGCGAGGUUCUGUUGUUUUCCAGAGGCUCCCACGGAGCAUGCUGGGUGGGUGGUCUGUAUGAGACCACACCGUUGAUGAGCAGUGAGGCCCAAACAGGUAUAUCAAAAAAUGCUCAGCAUCGCUGAUCAUCAGGGAAAUGCACAUCAUAAACACAGUGAGACGUUGCCUCACACCUGCCAGAAUGGCUACUGUCAGACGAAAGACAACAAGUGUGGGUGAGGAUGUGGAGAAAAGCGAACACUUGUCCACCUUUGGUGAGAAUGUAAAUUGGUAUAGCCAUUAUGGAAAACAGGAAGUUCCUGAAAAAAUUAAGAACAGCUACCAGGAAUCCCACAUCUGGGUGUAUAUCCAAAAGAAAUGAAGUCAGUACCUUGAAGAGAUCUCUGCAGCCCCUGUUCAUUGCAGCAUUAUUCACAAUAGCCAAGAUAGGGAAAAAGCCUCAGUGUCUACUGACAAAUAAAGAUGGAUCAAGAAAAUGCAUGUAUGUAUACACACACACAGUGGAAUACCAAGUCUUGCAGAAGAAGGAAAUCCUGUCAUUUGUGACAACAUGGAUGAGCUGAGAGAACAUUAUGCUAAGUGAAAUAAGCCAGACACAGAAAGAAAAAUACCAGAUGAUCUCACUUAUAUGUGGAAUCUAAAAAGGUUGGACUCAGAAGCAGAGAGUGGAAUGGUGGUUACCAAAGGCCAGAGGGUGCAGGAAGUGAGCAGAUGUUGGUGAAAGGGUGCAGAGGUUCAGCUAUGCAACAUGAAUGAAUUCUGGAGAUCCACUGUGCAGCAUGGUGACUAUGAUACUGCUUUGUGUAUUUAAAAUUUUCAGAGAGUAGAUCUUGUGUUCUUUCCCCUCUCCAAAUAAAAGGAAAUUAUUUGAGGUGAUGGAUAUGUUUAACUAGCUUGACUGGGGCAAUGAUUUUGUAAUGAUAAGUAUCUCAAAACAUCAUGUUGUACAACAUAAGUAUACAAUUGACCCUUGAACAAUACAGGUUUGAACUCUGUGGGUCCACUUACAUGCGGUUUUUUUUUUCUGUAAAAGUUACACCCGAUGCGUCAGCCCCUUCUUCUACCUCUUCCACCUCUGGCACCCUUGGCACAGCAAGACCAACCCCCCACUUCCUCCUCCUCCUCCUCAGCCUACUCAGGGUAAAGACAAGGAUGAAGACCUUUAUGAUGAUCCACUUCCACUUAAUAUAUAAUAAAUAUAUUUUCUCCUCAUGAUUUUCUUAAAACUUUUUCUGUAUUUUAUUGUAAGAAUACAGUAUAUAAUACAUACAACAUCGAAAA-3'- Poly-A tail
- Coding region
DNA
DNA (Gene ID: 3482)
insulin like growth factor 2 receptor
strand +
CD222, MPRI, MPR1, CIMPR, M6P-R, CI-M6PR, CI-MPR, MPR300
NCBI CDS gene sequence (7476 bp)
5'-ATGGGGGCCGCCGCCGGCCGGAGCCCCCACCTGGGGCCCGCGCCCGCCCGCCGCCCGCAGCGCTCTCTGCTCCTGCTGCAGCTGCTGCTGCTCGTCGCTGCCCCGGGGTCCACGCAGGCCCAGGCCGCCCCGTTCCCCGAGCTGTGCAGTTATACATGGGAAGCTGTTGATACCAAAAATAATGTACTTTATAAAATCAACATCTGTGGAAGTGTGGATATTGTCCAGTGCGGGCCATCAAGTGCTGTTTGTATGCACGACTTGAAGACACGCACTTATCATTCAGTGGGTGACTCTGTTTTGAGAAGTGCAACCAGATCTCTCCTGGAATTCAACACAACAGTGAGCTGTGACCAGCAAGGCACAAATCACAGAGTCCAGAGCAGCATTGCCTTCCTGTGTGGGAAAACCCTGGGAACTCCTGAATTTGTAACTGCAACAGAATGTGTGCACTACTTTGAGTGGAGGACCACTGCAGCCTGCAAGAAAGACATATTTAAAGCAAATAAGGAGGTGCCATGCTATGTGTTTGATGAAGAGTTGAGGAAGCATGATCTCAATCCTCTGATCAAGCTTAGTGGTGCCTACTTGGTGGATGACTCCGATCCGGACACTTCTCTATTCATCAATGTTTGTAGAGACATAGACACACTACGAGACCCAGGTTCACAGCTGCGGGCCTGTCCCCCCGGCACTGCCGCCTGCCTGGTAAGAGGACACCAGGCGTTTGATGTTGGCCAGCCCCGGGACGGACTGAAGCTGGTGCGCAAGGACAGGCTTGTCCTGAGTTACGTGAGGGAAGAGGCAGGAAAGCTAGACTTTTGTGATGGTCACAGCCCTGCGGTGACTATTACATTTGTTTGCCCGTCGGAGCGGAGAGAGGGCACCATTCCCAAACTCACAGCTAAATCCAACTGCCGCTATGAAATTGAGTGGATTACTGAGTATGCCTGCCACAGAGATTACCTGGAAAGTAAAACTTGTTCTCTGAGCGGCGAGCAGCAGGATGTCTCCATAGACCTCACACCACTTGCCCAGAGCGGAGGTTCATCCTATATTTCAGATGGAAAAGAATATTTGTTTTATTTGAATGTCTGTGGAGAAACTGAAATACAGTTCTGTAATAAAAAACAAGCTGCAGTTTGCCAAGTGAAAAAGAGCGATACCTCTCAAGTCAAAGCAGCAGGAAGATACCACAATCAGACCCTCCGATATTCGGATGGAGACCTCACCTTGATATATTTTGGAGGTGATGAATGCAGCTCAGGGTTTCAGCGGATGAGCGTCATAAACTTTGAGTGCAATAAAACCGCAGGTAACGATGGGAAAGGAACTCCTGTATTCACAGGGGAGGTTGACTGCACCTACTTCTTCACATGGGACACGGAATACGCCTGTGTTAAGGAGAAGGAAGACCTCCTCTGCGGTGCCACCGACGGGAAGAAGCGCTATGACCTGTCCGCGCTGGTCCGCCATGCAGAACCAGAGCAGAATTGGGAAGCTGTGGATGGCAGTCAGACGGAAACAGAGAAGAAGCATTTTTTCATTAATATTTGTCACAGAGTGCTGCAGGAAGGCAAGGCACGAGGGTGTCCCGAGGACGCGGCAGTGTGTGCAGTGGATAAAAATGGAAGTAAAAATCTGGGAAAATTTATTTCCTCTCCCATGAAAGAGAAAGGAAACATTCAACTCTCTTATTCAGATGGTGATGATTGTGGTCATGGCAAGAAAATTAAAACTAATATCACACTTGTATGCAAGCCAGGTGATCTGGAAAGTGCACCAGTGTTGAGAACTTCTGGGGAAGGCGGTTGCTTTTATGAGTTTGAGTGGCACACAGCTGCGGCCTGTGTGCTGTCTAAGACAGAAGGGGAGAACTGCACGGTCTTTGACTCCCAGGCAGGGTTTTCTTTTGACTTATCACCTCTCACAAAGAAAAATGGTGCCTATAAAGTTGAGACAAAGAAGTATGACTTTTATATAAATGTGTGTGGCCCGGTGTCTGTGAGCCCCTGTCAGCCAGACTCAGGAGCCTGCCAGGTGGCAAAAAGTGATGAGAAGACTTGGAACTTGGGTCTGAGTAATGCGAAGCTTTCATATTATGATGGGATGATCCAACTGAACTACAGAGGCGGCACACCCTATAACAATGAAAGACACACACCGAGAGCTACGCTCATCACCTTTCTCTGTGATCGAGACGCGGGAGTGGGCTTCCCTGAATATCAGGAAGAGGATAACTCCACCTACAACTTCCGGTGGTACACCAGCTATGCCTGCCCGGAGGAGCCCCTGGAATGCGTAGTGACCGACCCCTCCACGCTGGAGCAGTACGACCTCTCCAGTCTGGCAAAATCTGAAGGTGGCCTTGGAGGAAACTGGTATGCCATGGACAACTCAGGGGAACATGTCACGTGGAGGAAATACTACATTAACGTGTGTCGGCCTCTGAATCCAGTGCCGGGCTGCAACCGATATGCATCGGCTTGCCAGATGAAGTATGAAAAAGATCAGGGCTCCTTCACTGAAGTGGTTTCCATCAGTAACTTGGGAATGGCAAAGACCGGCCCGGTGGTTGAGGACAGCGGCAGCCTCCTTCTGGAATACGTGAATGGGTCGGCCTGCACCACCAGCGATGGCAGACAGACCACATATACCACGAGGATCCATCTCGTCTGCTCCAGGGGCAGGCTGAACAGCCACCCCATCTTTTCTCTCAACTGGGAGTGTGTGGTCAGTTTCCTGTGGAACACAGAGGCTGCCTGTCCCATTCAGACAACGACGGATACAGACCAGGCTTGCTCTATAAGGGATCCCAACAGTGGATTTGTGTTTAATCTTAATCCGCTAAACAGTTCGCAAGGATATAACGTCTCTGGCATTGGGAAGATTTTTATGTTTAATGTCTGCGGCACAATGCCTGTCTGTGGGACCATCCTGGGAAAACCTGCTTCTGGCTGTGAGGCAGAAACCCAAACTGAAGAGCTCAAGAATTGGAAGCCAGCAAGGCCAGTCGGAATTGAGAAAAGCCTCCAGCTGTCCACAGAGGGCTTCATCACTCTGACCTACAAAGGGCCTCTCTCTGCCAAAGGTACCGCTGATGCTTTTATCGTCCGCTTTGTTTGCAATGATGATGTTTACTCAGGGCCCCTCAAATTCCTGCATCAAGATATCGACTCTGGGCAAGGGATCCGAAACACTTACTTTGAGTTTGAAACCGCGTTGGCCTGTGTTCCTTCTCCAGTGGACTGCCAAGTCACCGACCTGGCTGGAAATGAGTACGACCTGACTGGCCTAAGCACAGTCAGGAAACCTTGGACGGCTGTTGACACCTCTGTCGATGGGAGAAAGAGGACTTTCTATTTGAGCGTTTGCAATCCTCTCCCTTACATTCCTGGATGCCAGGGCAGCGCAGTGGGGTCTTGCTTAGTGTCAGAAGGCAATAGCTGGAATCTGGGTGTGGTGCAGATGAGTCCCCAAGCCGCGGCGAATGGATCTTTGAGCATCATGTATGTCAACGGTGACAAGTGTGGGAACCAGCGCTTCTCCACCAGGATCACGTTTGAGTGTGCTCAGATATCGGGCTCACCAGCATTTCAGCTTCAGGATGGTTGTGAGTACGTGTTTATCTGGAGAACTGTGGAAGCCTGTCCCGTTGTCAGAGTGGAAGGGGACAACTGTGAGGTGAAAGACCCAAGGCATGGCAACTTGTATGACCTGAAGCCCCTGGGCCTCAACGACACCATCGTGAGCGCTGGCGAATACACTTATTACTTCCGGGTCTGTGGGAAGCTTTCCTCAGACGTCTGCCCCACAAGTGACAAGTCCAAGGTGGTCTCCTCATGTCAGGAAAAGCGGGAACCGCAGGGATTTCACAAAGTGGCAGGTCTCCTGACTCAGAAGCTAACTTATGAAAATGGCTTGTTAAAAATGAACTTCACGGGGGGGGACACTTGCCATAAGGTTTATCAGCGCTCCACAGCCATCTTCTTCTACTGTGACCGCGGCACCCAGCGGCCAGTATTTCTAAAGGAGACTTCAGATTGTTCCTACTTGTTTGAGTGGCGAACGCAGTATGCCTGCCCACCTTTCGATCTGACTGAATGTTCATTCAAAGATGGGGCTGGCAACTCCTTCGACCTCTCGTCCCTGTCAAGGTACAGTGACAACTGGGAAGCCATCACTGGGACGGGGGACCCGGAGCACTACCTCATCAATGTCTGCAAGTCTCTGGCCCCGCAGGCTGGCACTGAGCCGTGCCCTCCAGAAGCAGCCGCGTGTCTGCTGGGTGGCTCCAAGCCCGTGAACCTCGGCAGGGTAAGGGACGGACCTCAGTGGAGAGATGGCATAATTGTCCTGAAATACGTTGATGGCGACTTATGTCCAGATGGGATTCGGAAAAAGTCAACCACCATCCGATTCACCTGCAGCGAGAGCCAAGTGAACTCCAGGCCCATGTTCATCAGCGCCGTGGAGGACTGTGAGTACACCTTTGCCTGGCCCACAGCCACAGCCTGTCCCATGAAGAGCAACGAGCATGATGACTGCCAGGTCACCAACCCAAGCACAGGACACCTGTTTGATCTGAGCTCCTTAAGTGGCAGGGCGGGATTCACAGCTGCTTACAGCGAGAAGGGGTTGGTTTACATGAGCATCTGTGGGGAGAATGAAAACTGCCCTCCTGGCGTGGGGGCCTGCTTTGGACAGACCAGGATTAGCGTGGGCAAGGCCAACAAGAGGCTGAGATACGTGGACCAGGTCCTGCAGCTGGTGTACAAGGATGGGTCCCCTTGTCCCTCCAAATCCGGCCTGAGCTATAAGAGTGTGATCAGTTTCGTGTGCAGGCCTGAGGCCAGGCCAACCAATAGGCCCATGCTCATCTCCCTGGACAAGCAGACATGCACTCTCTTCTTCTCCTGGCACACGCCGCTGGCCTGCGAGCAAGCGACCGAATGTTCCGTGAGGAATGGAAGCTCTATTGTTGACTTGTCTCCCCTTATTCATCGCACTGGTGGTTATGAGGCTTATGATGAGAGTGAGGATGATGCCTCCGATACCAACCCTGATTTCTACATCAATATTTGTCAGCCACTAAATCCCATGCACGGAGTGCCCTGTCCTGCCGGAGCCGCTGTGTGCAAAGTTCCTATTGATGGTCCCCCCATAGATATCGGCCGGGTAGCAGGACCACCAATACTCAATCCAATAGCAAATGAGATTTACTTGAATTTTGAAAGCAGTACTCCTTGCTTAGCGGACAAGCATTTCAACTACACCTCGCTCATCGCGTTTCACTGTAAGAGAGGTGTGAGCATGGGAACGCCTAAGCTGTTAAGGACCAGCGAGTGCGACTTTGTGTTCGAATGGGAGACTCCTGTCGTCTGTCCTGATGAAGTGAGGATGGATGGCTGTACCCTGACAGATGAGCAGCTCCTCTACAGCTTCAACTTGTCCAGCCTTTCCACGAGCACCTTTAAGGTGACTCGCGACTCGCGCACCTACAGCGTTGGGGTGTGCACCTTTGCAGTCGGGCCAGAACAAGGAGGCTGTAAGGACGGAGGAGTCTGTCTGCTCTCAGGCACCAAGGGGGCATCCTTTGGACGGCTGCAATCAATGAAACTGGATTACAGGCACCAGGATGAAGCGGTCGTTTTAAGTTACGTGAATGGTGATCGTTGCCCTCCAGAAACCGATGACGGCGTCCCCTGTGTCTTCCCCTTCATATTCAATGGGAAGAGCTACGAGGAGTGCATCATAGAGAGCAGGGCGAAGCTGTGGTGTAGCACAACTGCGGACTACGACAGAGACCACGAGTGGGGCTTCTGCAGACACTCAAACAGCTACCGGACATCCAGCATCATATTTAAGTGTGATGAAGATGAGGACATTGGGAGGCCACAAGTCTTCAGTGAAGTGCGTGGGTGTGATGTGACATTTGAGTGGAAAACAAAAGTTGTCTGCCCTCCAAAGAAGTTGGAGTGCAAATTCGTCCAGAAACACAAAACCTACGACCTGCGGCTGCTCTCCTCTCTCACCGGGTCCTGGTCCCTCGTCCACAACGGAGTCTCGTACTATATAAATCTGTGCCAGAAAATATATAAAGGGCCCCTGGGCTGCTCTGAAAGGGCCAGCATTTGCAGAAGGACCACAACTGGTGACGTCCAGGTCCTGGGACTCGTTCACACGCAGAAGCTGGGTGTCATAGGTGACAAAGTTGTTGTCACGTACTCCAAAGGTTATCCGTGTGGTGGAAATAAGACCGCATCCTCCGTGATAGAATTGACCTGTACAAAGACGGTGGGCAGACCTGCATTCAAGAGGTTTGATATCGACAGCTGCACTTACTACTTCAGCTGGGACTCCCGGGCTGCCTGCGCCGTGAAGCCTCAGGAGGTGCAGATGGTGAATGGGACCATCACCAACCCTATAAATGGCAAGAGCTTCAGCCTCGGAGATATTTATTTTAAGCTGTTCAGAGCCTCTGGGGACATGAGGACCAATGGGGACAACTACCTGTATGAGATCCAACTTTCCTCCATCACAAGCTCCAGAAACCCGGCGTGCTCTGGAGCCAACATATGCCAGGTGAAGCCCAACGATCAGCACTTCAGTCGGAAAGTTGGAACCTCTGACAAGACCAAGTACTACCTTCAAGACGGCGATCTCGATGTCGTGTTTGCCTCTTCCTCTAAGTGCGGAAAGGATAAGACCAAGTCTGTTTCTTCCACCATCTTCTTCCACTGTGACCCTCTGGTGGAGGACGGGATCCCCGAGTTCAGTCACGAGACTGCCGACTGCCAGTACCTCTTCTCTTGGTACACCTCAGCCGTGTGTCCTCTGGGGGTGGGCTTTGACAGCGAGAATCCCGGGGACGACGGGCAGATGCACAAGGGGCTGTCAGAACGGAGCCAGGCAGTCGGCGCGGTGCTCAGCCTGCTGCTGGTGGCGCTCACCTGCTGCCTGCTGGCCCTGTTGCTCTACAAGAAGGAGAGGAGGGAAACAGTGATAAGTAAGCTGACCACTTGCTGTAGGAGAAGTTCCAACGTGTCCTACAAATACTCAAAGGTGAATAAGGAAGAAGAGACAGATGAGAATGAAACAGAGTGGCTGATGGAAGAGATCCAGCTGCCTCCTCCACGGCAGGGAAAGGAAGGGCAGGAGAACGGCCATATTACCACCAAGTCAGTGAAAGCCCTCAGCTCCCTGCATGGGGATGACCAGGACAGTGAGGATGAGGTTCTGACCATCCCAGAGGTGAAAGTTCACTCGGGCAGGGGAGCTGGGGCAGAGAGCTCCCACCCAGTGAGAAACGCACAGAGCAATGCCCTTCAGGAGCGTGAGGACGATAGGGTGGGGCTGGTCAGGGGTGAGAAGGCGAGGAAAGGGAAGTCCAGCTCTGCACAGCAGAAGACAGTGAGCTCCACCAAGCTGGTGTCCTTCCATGACGACAGCGACGAGGACCTCTTACACATCTGA-3'
By using this site you agree to our privacy policy.
Please confirm you agree with the privacy policy before using the site.