Protein
Protein (NP_001030017)
CBM13-ppGalNAc-TL6
Polypeptide N-acetylgalactosaminyltransferase-like 6 (EC 2.4.1.41) (Polypeptide GalNAc transferase 17) (GalNAc-T17) (pp-GaNTase 17) (Protein-UDP acetylgalactosaminyltransferase 17) (Putative polypeptide N-acetylgalactosaminyltransferase 17) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 17)
GALNTL6
polypeptide N-acetylgalactosaminyltransferase like 6
Undefined
Curated
Ricin-like
Undefined
b-trefoil
GalNAc / Mucin-type glycopeptide
NP_001030017
442117
Q49A17
ENSP00000423313.1
Q49A17
Undefined
10.1074/jbc.M111.273722
neXtProt, PFAM, InterPro
Protein sequence and protein families (fasta) (601 amino acids) Download
MKRKQKRFLQMTLLFTVALIFLPNVGLWSLYKDKHLVKSAEPGEQQTFPLGLGDGQFYSWTDGLRRKDWHDYESIQKEAMRSGKGEHGKPYPLTEEDHDDSAYRENGFNIFVSNNIALERSLPDIRHANCKHKMYLERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPGSLIAEIILVDDFSEREHLKDKLEEYMARFSKVRIVRTKKREGLIRTRLLGASMARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYVPYKVPSGTSLARNLKRVAETWMDEFAEYIYQRRPEYRHLSTGDISAQKELRKQLKCKDFKWFMAAVAWDVPKYYPPVEPPPAAWGEIRNVAANLCVDSKHGATGTELRLDICVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKFCFDAISHNSPVTLYDCHGMKGNQLWGYRKDRTLFHPVSNSCMDCNPAEKKIFMARCDPLSETQQWIFEHINMTVLEKFNHHANS
No structure currently available in the PDB RCSB Databank.
Structural models
AlphaFold v2: AF-Q49A17-F1Download
  Model Confidence:
  •    Very high (pLDDT > 90)
  •    Confident (90 > pLDDT > 70)
  •    Low (70 > pLDDT > 50)
  •    Very low (pLDDT < 50)

  AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

SWISS-MODEL structural models
SWISS-MODEL structural model
Modeller structural model (Homology modelling pipeline), Error: [1.52, 1.95] ÅDownload
The location of the lectin domain structural model is: 453-586
We infer [1.52, 1.95] Å as the interval of error of this structural model.
Template: 1XHB chain: A, O08912, NP_001153876.1, sequence identity: 30.6%, coverage: 91.0%, location in sequence: 95-553, (95-553 in PDB).
Show the alignment used for the construction of the structural model, Download.
Show the plot of DOPE energy score, Download.
Ligand
Glycan ligands from structural data
No crystal structures of complexes with glycan ligand.
Expression
Human Protein Atlas
GeneCards
mRNA expression in normal human tissues for GALNTL6 Gene
ProteomicsDB
References
NCBI References (4 PubMed Identifiers)
  • The GALNTL6 Gene rs558129 Polymorphism Is Associated With Power Performance. [33105351]
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases: completion of the family tree. [22186971]
  • Identification of a novel human UDP-GalNAc transferase with unique catalytic activity and expression profile. [20977886]
  • Molecular genetics of successful smoking cessation: convergent genome-wide association study results. [18519826]
UniProt Main References (2 PubMed Identifiers)
  • Generation and annotation of the DNA sequences of human chromosomes 2 and 4. [15815621]
  • The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). [15489334]
All isoforms of this gene containing a lectin domain
XP_011530299.1, XP_011530296.1, XP_011530297.1, XP_011530298.1, XP_011530295.1, NP_001030017.2, XP_016863733.1
RNA
RNA (Transcript ID: NM_001034845.3)
NM_001034845.3
polypeptide N-acetylgalactosaminyltransferase like 6
All isoforms of GALNTL6 containing a lectin domain
ENST00000506823.6
757..2562 (or 171814581.. 173040100)
171813404.. 173041559
NCBI Matured mRNA sequence 4021 NTPDownload 
m7G-5')ppp(5'-GCAGACACCAGCGACGUCUCCGCGGAAGGCAGGCGCCGGGGAGUGGGGCGCGGGCGACCGUGUGCAGCCGCGGCGCAUCUCCGCCUUCCGCUCCUCCUCGCAGCGCCCUCGUCCGCUUCCAAGCCCAGCACAGACUUCGGUUUCUCCGCCUCCAUCCCCUUUACGAGAAGAGGAGAUCAAAAAAUAUUGCCCUUUAGGUGCUCGUGAUGGUCCUGUGGGUUCGUUCAGUUGCCAGAAAAGAAUGGUAACAUGAACAGCGGAGCGUGAGAGCGUCACCGGGGGAAGGGACGAGAUUGAUGGGCAGAGCGCUCACUUCUCAGAGGAUCGCAUUCCGAGGACCGCGCGAGGAAGGGACGUCGCGGCGCCACCACUUCCUGGCUGGACUCCGCUGACAUCUGUAGCCUCCUUUCCACCAGGUUCCCGGGGCUCCCAGCCGCUGCCUGCAGAGGAGCGUGUAGACAGCGCGCGAGGGUCCGGCACUUCGUGGACCUCCAUCCGAACCGGAGUUCUGCCCGGAUCCCGAGUCCCUGGAUCCCGGUGGAGCCCGCCGGCAAGCUGGCUCCGGAGGGAGUUGAACUUGAGUUCAGAUGGCCAACUCCCUCUGAAUCCUGCAGAUUGGUGCUGAGCACGCAACAAAAGUUUGUAGCUUCUCAGUUUCUGGUGCUUCGCAGGGGAGAGGAAAGGAAUUUGACAUUAAACACAAGAAGCAGUCAGGGAGCCAUCUCCUUUAACUUUUCUUCUCUGUUACCAUUUGCAAUGAAGAGGAAACAGAAGAGAUUUCUGCAGAUGACUUUGUUGUUCACGGUGGCUUUAAUUUUCCUGCCUAACGUUGGUCUCUGGUCUCUGUACAAGGAUAAGCACCUGGUGAAGUCAGCGGAGCCCGGGGAGCAGCAGACAUUUCCACUGGGCCUGGGAGAUGGGCAAUUCUAUUCAUGGACAGAUGGUUUGAGAAGAAAGGACUGGCAUGACUAUGAAAGCAUUCAGAAAGAGGCUAUGCGCUCAGGGAAAGGUGAACAUGGGAAACCUUACCCCCUUACUGAAGAGGACCAUGAUGACUCAGCUUACAGGGAAAAUGGUUUUAAUAUUUUCGUCAGCAACAAUAUUGCUCUAGAGAGGUCUCUGCCAGAUAUUCGUCAUGCUAACUGUAAGCAUAAGAUGUAUCUGGAAAGGCUGCCAAACACCAGCAUCAUUAUCCCAUUUCAUAAUGAAGGUUGGACUUCACUCCUGCGGACCAUACACAGUAUAAUUAACCGAACCCCAGGGAGUCUGAUAGCAGAAAUCAUUCUAGUAGAUGACUUCAGUGAGAGAGAACACCUGAAGGAUAAAUUGGAAGAAUACAUGGCCCGAUUUUCCAAAGUGAGGAUUGUUCGCACCAAGAAAAGAGAAGGACUCAUCCGGACCCGUCUCCUGGGGGCAUCUAUGGCCAGAGGAGAAGUCCUGACAUUCCUGGACUCCCACUGCGAGGUCAAUGUGAACUGGCUGCCCCCACUCCUCAACCAAAUUGCACUAAACCACAAAACCAUCGUGUGUCCCAUGAUCGAUGUCAUUGACCACAAUCACUUCGGGUAUGAGGCACAAGCUGGGGAUGCCAUGCGAGGAGCCUUCGACUGGGAAAUGUACUACAAAAGAAUCCCCAUCCCUCCAGAGCUCCAGAGGGCAGAUCCCAGCGACCCUUUUGAGUCUCCUGUUAUGGCUGGAGGUCUCUUUGCUGUGGAUCGGAAAUGGUUUUGGGAAUUGGGUGGCUAUGAUCCAGGUUUAGAAAUCUGGGGAGGAGAACAGUAUGAAAUCUCUUUUAAGGUUUGGAUGUGUGGAGGAGAAAUGUUUGAUGUUCCAUGUUCUAGAGUUGGUCAUAUCUACAGGAAGUACGUUCCAUACAAAGUUCCAUCUGGGACAAGCCUGGCAAGAAACCUGAAGCGGGUAGCUGAGACCUGGAUGGAUGAAUUUGCCGAGUACAUUUACCAGCGGCGGCCGGAGUACAGGCAUCUCUCCACGGGGGACAUCUCUGCCCAGAAGGAGCUGCGCAAGCAGCUCAAGUGCAAGGACUUCAAAUGGUUCAUGGCUGCUGUGGCCUGGGACGUGCCUAAAUACUACCCUCCAGUGGAGCCCCCGCCUGCUGCCUGGGGGGAGAUCCGAAAUGUGGCAGCAAAUCUCUGUGUGGACAGCAAGCAUGGAGCCACCGGAACAGAGCUGAGGCUGGACAUCUGUGUCAAGGAUGGUUCUGAAAGAACAUGGUCUCAUGAACAGCUUUUUACCUUUGGAUGGAGAGAAGAUAUUCGACCCGGUGAGCCACUGCAUACCCGGAAAUUCUGCUUUGAUGCGAUCUCACACAACAGCCCCGUUACACUCUAUGACUGUCAUGGCAUGAAGGGGAACCAGCUCUGGGGAUACCGGAAGGACAGAACAUUAUUCCAUCCUGUGAGCAACAGCUGCAUGGAUUGCAACCCCGCAGAGAAGAAGAUUUUCAUGGCCAGAUGUGACCCUCUCUCUGAGACUCAGCAGUGGAUUUUUGAACACAUUAAUAUGACUGUUUUAGAAAAAUUUAACCACCAUGCCAACUCCUAGAAAGAAGAAAGGAAGAAAGAGUGAUUACCUACAGGUUAUAAAUUAAAUUUUAGCCAGCAUCUGGGUCGAAGGAGUCAGGAAUAACAUUUCCUCGAUCCAGGAAGGCUGGUUUAAAAAUUUGCAAAUGCCAUGUCAAAGUAGGUUGUUUUGAAGAACUUCCUGCAUCUGAAGAACUUGGCUGAGAAUCUCACCAGCUGCUUCUGAGAACUCGAGACUAGCAGUUCCCUUGCUGGCCAAGGGCAAAGAUAAUUUAGGGACUUUUCAAAACAACUGCUGAGCUAAUAAAUCCUAGCAUUUCUCAGGUCAAAUCCUGCAGUAGUGAGUAGCUAUGAAUGGAUCCUAUUAACUGGGUGGGAGGGGGGUGAAAAUGGAGUGCAUGACUGCUCUGACAACCUGAGGAUAUCACAGGUUUAGAACUAGCCAAGCUUAAGGGGUGAGCUGUACUCUUUGGUGCCAUUCUCUGACUAAGAAUGGGUUCAGCAGGUUUAACCCUUAAAAGUGCUGCAGAUGAUUUCAGAGUGCUCACACUAUUCUGUUUUUUUUAUUUUUAUUUUUAAAUGAGGGUGCAAUAUCUAAUGUAAGACUUAAAUUACAUAAUGAAAUGGACAUCCAGUGUUCCCAUUCUUUCGUUUAUAUUUGCCAUUUUUUUUUCAGAGCAAAGUUUCUUUUUUAUGAAAGUUCAUGCUCCAUGAAUCCACUGAAUUUCUAAUUCAGUGCCCUUCUAUGAAUCCAGUUAAAAACAAAAGCAAAAGCAAAAAUCUAUGCUAUCAAGUUACUCCAAAGAAAGAUUUCACAGAAGCAGCAAAACCAUAUAAGAUUUAGGAGAGGGACUUCCCUGGGAAAUCUAUUUUUACUUUUCUAUUAUUUUUAAAAUCUUAAAAGUCUGAUAUUUGUCCAGUCAUAAUUUUUAUUAAGCAAGGAAAUGGAGUGAGUUUGAUGUAAUUUGUUUAGGAGAUUCUUAAACCCAAAUAAAUCUACACUCCAAGUGAUAUGUGAAAAUGGCUUAGUUCACUUCAAUUCUGUUUAGUCAGUGGUGGGAGCUUAGAAGUGGUUUUAUUUGUUCGUUUGUUUGGGUUUUGCUUUUGUUUUUUAUUUUUUUCUUGUUUUUUUUUUGUAGUGUUGAAUUAAUGAUGUUCUUUUAUUUGGAAGCUCAUAAAAGGAAUUACCAUUAAUAAAGUGUUUCUGACACCAUUUUCUGUUAAUGGGACAAUAUUUCGGGGAUGAAGAAAGGAAUGCUCCGAAAACUAAAUGGAACACUUAAUCCUUAAAGCAAUUUUUUACUGUUCAAUAAUAUCACAUUGGGGGAAGAAAACACAGGUAUCAAGGUGGUUCUUGGGAAAAAAGAAUCAUGUUUAUUAUAUAUCUCUCAAGUUUUUUUGGUAUAAAAAUGUUUUAACUUUGCUUUCUUUUUGGUUUUUGUUUGAAGUUGGUUUUCCUGUUAAUAAAAAUUUAUAUAACA-3'- Poly-A tail
  • Coding region
NCBI Matured mRNA sequence viewer
;
More about the NCBI sViewer.
DNA
DNA (Gene ID: 442117)
GALNTL6
polypeptide N-acetylgalactosaminyltransferase like 6
NC_000004.12
4  171814581.. 173040100
171814581.. 173040100
strand +
CCDS34104.1
MGI:1913581
ClinVar, dbVar
ENSG00000174473
GALNT17, GalNAc-T6L
uc003isv.4
INSDC:
33844
615138
OTTHUMG00000160807
ENA, DDBJ, Monarch
NCBI CDS Gene viewer
More about the NCBI sViewer.
NCBI CDS gene sequence (1806 bp)
5'-ATGAAGAGGAAACAGAAGAGATTTCTGCAGATGACTTTGTTGTTCACGGTGGCTTTAATTTTCCTGCCTAACGTTGGTCTCTGGTCTCTGTACAAGGATAAGCACCTGGTGAAGTCAGCGGAGCCCGGGGAGCAGCAGACATTTCCACTGGGCCTGGGAGATGGGCAATTCTATTCATGGACAGATGGTTTGAGAAGAAAGGACTGGCATGACTATGAAAGCATTCAGAAAGAGGCTATGCGCTCAGGGAAAGGTGAACATGGGAAACCTTACCCCCTTACTGAAGAGGACCATGATGACTCAGCTTACAGGGAAAATGGTTTTAATATTTTCGTCAGCAACAATATTGCTCTAGAGAGGTCTCTGCCAGATATTCGTCATGCTAACTGTAAGCATAAGATGTATCTGGAAAGGCTGCCAAACACCAGCATCATTATCCCATTTCATAATGAAGGTTGGACTTCACTCCTGCGGACCATACACAGTATAATTAACCGAACCCCAGGGAGTCTGATAGCAGAAATCATTCTAGTAGATGACTTCAGTGAGAGAGAACACCTGAAGGATAAATTGGAAGAATACATGGCCCGATTTTCCAAAGTGAGGATTGTTCGCACCAAGAAAAGAGAAGGACTCATCCGGACCCGTCTCCTGGGGGCATCTATGGCCAGAGGAGAAGTCCTGACATTCCTGGACTCCCACTGCGAGGTCAATGTGAACTGGCTGCCCCCACTCCTCAACCAAATTGCACTAAACCACAAAACCATCGTGTGTCCCATGATCGATGTCATTGACCACAATCACTTCGGGTATGAGGCACAAGCTGGGGATGCCATGCGAGGAGCCTTCGACTGGGAAATGTACTACAAAAGAATCCCCATCCCTCCAGAGCTCCAGAGGGCAGATCCCAGCGACCCTTTTGAGTCTCCTGTTATGGCTGGAGGTCTCTTTGCTGTGGATCGGAAATGGTTTTGGGAATTGGGTGGCTATGATCCAGGTTTAGAAATCTGGGGAGGAGAACAGTATGAAATCTCTTTTAAGGTTTGGATGTGTGGAGGAGAAATGTTTGATGTTCCATGTTCTAGAGTTGGTCATATCTACAGGAAGTACGTTCCATACAAAGTTCCATCTGGGACAAGCCTGGCAAGAAACCTGAAGCGGGTAGCTGAGACCTGGATGGATGAATTTGCCGAGTACATTTACCAGCGGCGGCCGGAGTACAGGCATCTCTCCACGGGGGACATCTCTGCCCAGAAGGAGCTGCGCAAGCAGCTCAAGTGCAAGGACTTCAAATGGTTCATGGCTGCTGTGGCCTGGGACGTGCCTAAATACTACCCTCCAGTGGAGCCCCCGCCTGCTGCCTGGGGGGAGATCCGAAATGTGGCAGCAAATCTCTGTGTGGACAGCAAGCATGGAGCCACCGGAACAGAGCTGAGGCTGGACATCTGTGTCAAGGATGGTTCTGAAAGAACATGGTCTCATGAACAGCTTTTTACCTTTGGATGGAGAGAAGATATTCGACCCGGTGAGCCACTGCATACCCGGAAATTCTGCTTTGATGCGATCTCACACAACAGCCCCGTTACACTCTATGACTGTCATGGCATGAAGGGGAACCAGCTCTGGGGATACCGGAAGGACAGAACATTATTCCATCCTGTGAGCAACAGCTGCATGGATTGCAACCCCGCAGAGAAGAAGATTTTCATGGCCAGATGTGACCCTCTCTCTGAGACTCAGCAGTGGATTTTTGAACACATTAATATGACTGTTTTAGAAAAATTTAACCACCATGCCAACTCCTAG-3'
NCBI CDS gene sequence with introns (location: 171814581.. 173040100) (1225520 bp)Download
NCBI Gene Viewer (CDS + introns)
NCBI CDS gene sequence with introns, 5'UTR and 3'UTR (location: 171813404.. 173041559) (1228156 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions)
NCBI gene sequence (location: [171813404 - 1000].. 173041559) (1229156 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions + 1000 dNTP to potentially reach the promotor)
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