NCBI Summary
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008].
Protein
Protein (NP_001008701)
Latrophilin-1 - adhesion G protein-coupled receptor L1
Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) (Lectomedin-2)
ADGRL1
adhesion G protein-coupled receptor L1
Undefined
Very low evidence
L-rhamnose binding lectin
Undefined
b-sandwich / CUB-like
Uncharacterised
NP_001008701
22859
O94910
Undefined
O88917
0.675
10.1016/j.str.2008.02.020
neXtProt, PFAM, InterPro
Protein sequence and protein families (fasta) (1474 amino acids) Download
MARLAAVLWNLCVTAVLVTSATQGLSRAGLPFGLMRRELACEGYPIELRCPGSDVIMVENANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRTQCVVVAGSDAFPDPCPGTYKYLEVQYDCVPYKVEQKVFVCPGTLQKVLEPTSTHESEHQSGAWCKDPLQAGDRIYVMPWIPYRTDTLTEYASWEDYVAARHTTTYRLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGETVINTANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEGNNGRLVVSQLNPYTLRFEGTWETGYDKRSASNAFMVCGVLYVLRSVYVDDDSEAAGNRVDYAFNTNANREEPVSLTFPNPYQFISSVDYNPRDNQLYVWNNYFVVRYSLEFGPPDPSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQLGPDLPPATAPVPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCLPALGLWNPRGPDLSNCTSPWVNQVAQKIKSGENAANIASELARHTRGSIYAGDVSSSVKLMEQLLDILDAQLQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQEEYPRKNSIQLSAKTIKQNSRNGVVKVVFILYNNLGLFLSTENATVKLAGEAGPGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEYSKCLRHSYCCIRSPPGGTHGSLKTSAMRSNTRYYTGTQSRIRRMWNDTVRKQTESSFMAGDINSTPTLNRGTMGNHLLTNPVLQPRGGTSPYNTLIAESVGFNPSSPPVFNSPGSYREPKHPLGGREACGMDTLPLNGNFNNSYSLRSGDFPPGDGGPEPPRGRNLADAAAFEKMIISELVHNNLRGSSSAAKGPPPPEPPVPPVPGGGGEEEAGGPGGADRAEIELLYKALEEPLLLPRAQSVLYQSDLDESESCTAEDGATSRPLSSPPGRDSLYASGANLRDSPSYPDSSPEGPSEALPPPPPAPPGPPEIYYTSRPPALVARNPLQGYYQVRRPSHEGYLAAPGLEGPGPDGDGQMQLVTSL
No structure currently available in the PDB RCSB Databank.
Structural models
AlphaFold v2: AF-O94910-F1Download
  Model Confidence:
  •    Very high (pLDDT > 90)
  •    Confident (90 > pLDDT > 70)
  •    Low (70 > pLDDT > 50)
  •    Very low (pLDDT < 50)

  AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

SWISS-MODEL structural models
SWISS-MODEL structural model
Modeller structural model (Homology modelling pipeline), Error: [0.28, 0.77] ÅDownload
The location of the lectin domain structural model is: 39-134
We infer [0.28, 0.77] Å as the interval of error of this structural model.
Template: 2JX9 chain: A, Q80TR1, NP_851382.2, sequence identity: 96.9%, coverage: 100.0%, location in sequence: 29-134, (29-134 in PDB).
Show the alignment used for the construction of the structural model, Download.
Show the plot of DOPE energy score, Download.
Ligand
Glycan ligands from structural data
No crystal structures of complexes with glycan ligand.
Expression
Human Protein Atlas
GeneCards
mRNA expression in normal human tissues for ADGRL1 Gene
ProteomicsDB
References
NCBI References (10 PubMed Identifiers)
  • Alternative splicing event modifying ADGRL1/latrophilin-1 cytoplasmic tail promotes both opposing and dual cAMP signaling pathways. [31339586]
  • Proteolytically released Lasso/teneurin-2 induces axonal attraction by interacting with latrophilin-1 on axonal growth cones. [30457553]
  • Cortisol facilitates the immune escape of human acute myeloid leukemia cells by inducing latrophilin 1 expression. [29907881]
  • Overexpression of the ABCB1 drug transporter in acute myeloid leukemia cells is associated with downregulation of latrophilin-1. [29938681]
  • Latrophilin receptors: novel bronchodilator targets in asthma. [27325752]
  • Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. [15144186]
  • The multiple actions of black widow spider toxins and their selective use in neurosecretion studies. [15066411]
  • alpha-Latrotoxin and its receptors: neurexins and CIRL/latrophilins. [11520923]
  • The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins. [10964907]
  • A family of heptahelical receptors with adhesion-like domains: a marriage between two super families. [10994649]
UniProt Main References (2 PubMed Identifiers)
  • Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. [10048485]
  • The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). [15489334]
All isoforms of this gene containing a lectin domain
NP_001008701.1, XP_011526098.1, NP_055736.2, XP_005259875.1, XP_011526100.1, XP_016881970.1, XP_016881968.1, XP_016881967.1, XP_016881966.1, XP_016881964.1, XP_016881965.1, XP_024307188.1
RNA
RNA (Transcript ID: NM_001008701.3)
NM_001008701.3
adhesion G protein-coupled receptor L1, transcript variant 1
All isoforms of ADGRL1 containing a lectin domain
281..4705 (or 14150873.. 14183602)
14147743.. 14206169
NCBI Matured mRNA sequence 7835 NTPDownload 
m7G-5')ppp(5'-CUAAUUUUUGGUCGGCGGCGGUGCUGGGCCAGGGGAAGGAAGGGACACGGAGGCCGCCCUCGUCCCGCCACCUCCUACCCGCUUCCCCCCAGCCCCGGCUCCGGGAGAUGUGCCGGGCGGGGGGCCCGGGUUCGCCGAGCCGCAGGAGAGACACGCUGGGCCGACCCCAGAGAGGCGCUGGACAGGCUGGUGGUCCAGGCCGUGGUGCCUGCCAGGUGAUGUGGGGCAAAGCCCCCCGCACAGGCCACUGAGAGCUCCGGACACGCACCCGGCUGCCACCAUGGCCCGCCUAGCCGCAGUGCUCUGGAAUCUGUGUGUCACCGCCGUCCUGGUCACCUCGGCCACCCAAGGCCUGAGCCGGGCCGGGCUCCCGUUCGGGCUGAUGCGCCGGGAGCUGGCGUGUGAAGGCUACCCCAUCGAGCUGCGGUGCCCCGGCAGCGACGUCAUCAUGGUGGAGAAUGCCAACUACGGGCGCACGGACGACAAGAUUUGCGAUGCUGACCCUUUCCAGAUGGAGAAUGUGCAGUGCUACCUGCCGGACGCCUUCAAGAUCAUGUCACAGAGGUGUAACAACCGCACCCAGUGCGUGGUGGUCGCCGGCUCGGAUGCCUUUCCUGACCCCUGUCCUGGGACCUACAAGUACCUGGAGGUGCAGUACGACUGUGUCCCCUACAAAGUGGAGCAGAAAGUCUUCGUGUGCCCAGGGACCCUGCAGAAGGUGCUGGAGCCCACCUCGACACACGAGUCAGAGCACCAGUCUGGCGCAUGGUGCAAGGACCCGCUGCAGGCGGGUGACCGCAUCUACGUGAUGCCCUGGAUCCCCUACCGCACGGACACACUGACUGAGUAUGCCUCGUGGGAGGACUACGUGGCCGCCCGCCACACCACCACCUACCGCCUGCCCAACCGCGUGGAUGGCACAGGCUUUGUGGUCUACGAUGGUGCCGUCUUCUACAACAAGGAGCGCACGCGCAACAUCGUCAAGUAUGACCUACGGACGCGCAUCAAGAGCGGGGAGACGGUCAUCAAUACCGCCAACUACCAUGACACCUCGCCCUACCGCUGGGGCGGAAAGACCGACAUUGACCUGGCGGUGGACGAGAACGGGCUGUGGGUCAUCUACGCCACUGAGGGCAACAACGGGCGGCUGGUGGUGAGCCAGCUGAACCCCUACACACUGCGCUUUGAGGGCACGUGGGAGACGGGUUACGACAAGCGCUCGGCAUCCAACGCCUUCAUGGUGUGUGGGGUCCUGUACGUCCUGCGUUCCGUGUACGUGGAUGAUGACAGCGAGGCGGCUGGCAACCGCGUGGACUAUGCCUUCAACACCAAUGCCAACCGCGAGGAGCCUGUCAGCCUCACCUUCCCCAACCCCUACCAGUUCAUCUCCUCCGUUGACUACAACCCUCGCGACAACCAGCUGUACGUCUGGAACAACUAUUUCGUGGUGCGCUACAGCCUGGAGUUCGGGCCGCCCGACCCCAGUGCUGGCCCAGCCACUUCCCCACCCCUCAGCACGACCACCACAGCCAGGCCCACGCCCCUCACCAGCACAGCCUCGCCCGCAGCCACCACCCCGCUCCGCCGGGCACCCCUCACCACGCACCCAGUGGGUGCCAUCAACCAGCUGGGACCUGAUCUGCCUCCAGCCACAGCCCCAGUCCCCAGCACCCGGCGGCCCCCAGCCCCGAAUCUACACGUGUCCCCUGAGCUCUUCUGCGAGCCCCGAGAGGUACGGCGGGUCCAGUGGCCGGCCACCCAGCAGGGCAUGCUGGUGGAGAGGCCCUGCCCCAAGGGGACUCGAGGAAUUGCCUCCUUCCAGUGUCUACCAGCCUUGGGGCUCUGGAACCCCCGGGGCCCUGACCUCAGCAACUGCACCUCCCCCUGGGUCAACCAGGUGGCCCAGAAGAUCAAGAGUGGGGAGAACGCGGCCAACAUCGCCAGCGAGCUGGCCCGACACACCCGGGGCUCCAUCUACGCGGGGGACGUCUCCUCCUCUGUGAAGCUGAUGGAGCAGCUGCUGGACAUCCUGGAUGCCCAGCUGCAGGCCCUGCGGCCCAUCGAGCGCGAGUCAGCCGGCAAGAACUACAACAAGAUGCACAAGCGAGAGAGAACUUGUAAGGAUUAUAUCAAGGCCGUGGUGGAGACAGUGGACAAUCUGCUCCGGCCAGAAGCUCUGGAGUCCUGGAAGGACAUGAAUGCCACGGAGCAGGUGCACACGGCCACCAUGCUCCUCGACGUCCUGGAGGAGGGCGCCUUCCUGCUGGCCGACAAUGUCAGGGAGCCUGCCCGCUUCCUGGCUGCCAAGGAGAACGUGGUCCUGGAGGUCACAGUCCUGAACACAGAGGGCCAGGUGCAGGAGCUGGUGUUCCCCCAGGAGGAGUACCCGAGAAAGAACUCCAUCCAGCUGUCUGCCAAAACCAUCAAGCAGAACAGCCGCAAUGGGGUGGUCAAAGUUGUCUUCAUCCUCUACAACAACCUGGGCCUCUUCCUGUCCACGGAGAAUGCCACAGUGAAGCUGGCCGGCGAAGCAGGCCCGGGUGGCCCUGGGGGCGCCUCUCUAGUGGUGAACUCACAGGUCAUCGCAGCAUCCAUCAACAAGGAGUCCAGCCGCGUCUUCCUCAUGGACCCUGUCAUCUUCACCGUGGCCCACCUGGAGGACAAGAACCACUUCAAUGCUAACUGCUCCUUCUGGAACUACUCGGAGCGUUCCAUGCUGGGCUACUGGUCGACCCAAGGCUGCCGCCUGGUGGAGUCCAACAAGACCCAUACCACGUGUGCCUGCAGCCACCUCACCAACUUCGCUGUGCUCAUGGCUCACCGUGAGAUCUACCAGGGCCGCAUCAACGAGCUGCUGCUGUCGGUCAUCACCUGGGUGGGCAUUGUGAUCUCCCUGGUCUGCUUGGCCAUCUGCAUCUCCACCUUCUGCUUCCUGCGGGGGCUGCAGACCGACCGCAACACCAUCCACAAGAACCUGUGCAUCAACCUCUUCCUGGCUGAGCUGCUCUUCCUGGUCGGGAUCGACAAGACUCAGUAUGAGAUUGCCUGCCCCAUCUUCGCCGGCCUGCUGCACUAUUUCUUCCUGGCUGCCUUCUCCUGGCUGUGCCUGGAGGGCGUGCACCUCUACCUGCUACUAGUGGAGGUGUUUGAGAGCGAGUAUUCCCGCACCAAGUACUACUACCUGGGUGGCUACUGCUUCCCGGCCCUGGUGGUGGGCAUCGCGGCUGCCAUUGACUACCGCAGCUACGGCACCGAGAAGGCCUGCUGGCUCCGAGUGGACAAUUACUUCAUCUGGAGUUUCAUCGGGCCAGUCUCCUUCGUUAUCGUGGUCAACCUGGUGUUCCUCAUGGUGACCCUGCACAAGAUGAUCCGAAGCUCAUCUGUGCUCAAGCCCGACUCCAGCCGCCUGGACAACAUUAAAUCCUGGGCGCUGGGGGCCAUCGCGCUGCUGUUCCUGCUGGGCCUCACCUGGGCUUUCGGCCUCCUCUUCAUCAACAAGGAGUCGGUGGUCAUGGCCUAUCUCUUCACCACCUUCAACGCCUUCCAGGGGGUCUUCAUCUUCGUCUUUCACUGCGCCUUACAGAAGAAGGUGCACAAGGAGUACAGCAAGUGCCUGCGUCACUCCUACUGCUGCAUCCGCUCCCCACCCGGGGGCACUCACGGAUCCCUCAAGACCUCAGCCAUGCGAAGCAACACCCGCUACUACACAGGGACCCAGAGCCGAAUUCGGAGGAUGUGGAAUGACACUGUGAGGAAACAGACGGAGUCCUCCUUCAUGGCGGGUGACAUCAACAGCACCCCCACCCUGAACCGAGGUACCAUGGGGAACCACCUGCUGACCAACCCCGUGCUGCAGCCCCGUGGGGGCACCAGUCCCUACAACACCCUCAUCGCCGAGUCAGUGGGCUUCAAUCCCUCCUCGCCCCCUGUCUUCAACUCCCCAGGGAGCUACCGGGAACCCAAGCACCCCUUGGGAGGCCGGGAAGCCUGUGGCAUGGACACCCUGCCCCUGAACGGCAACUUCAAUAACAGUUACUCCUUGCGAAGUGGGGAUUUCCCUCCCGGGGAUGGGGGCCCUGAGCCGCCCCGAGGCCGGAACCUAGCCGAUGCGGCGGCCUUUGAGAAGAUGAUCAUCUCAGAGCUGGUGCACAACAACCUGCGGGGGAGCAGCAGCGCGGCCAAGGGCCCUCCACCGCCUGAGCCCCCUGUGCCACCUGUGCCAGGGGGCGGGGGCGAGGAAGAGGCGGGCGGGCCCGGGGGUGCUGACCGGGCCGAGAUUGAACUUCUCUAUAAGGCCCUGGAGGAGCCUCUGCUGCUGCCCCGGGCCCAGUCGGUGCUGUACCAGAGCGAUCUGGACGAGUCGGAGAGCUGCACGGCCGAGGACGGCGCCACCAGCCGGCCCCUCUCCUCCCCUCCUGGCCGGGACUCCCUCUAUGCCAGCGGGGCCAACCUGCGGGACUCACCCUCCUACCCGGACAGCAGCCCUGAGGGGCCCAGUGAGGCCCUGCCCCCACCCCCUCCCGCACCCCCCGGCCCCCCCGAAAUCUACUACACCUCGCGCCCGCCAGCCCUGGUGGCCCGGAAUCCCCUGCAGGGCUACUACCAGGUGCGGCGUCCUAGCCACGAGGGCUACCUGGCAGCCCCAGGCCUUGAGGGGCCAGGGCCCGAUGGGGACGGGCAGAUGCAGCUGGUCACCAGUCUCUGAGGGCACCUCAUGGACCAGGGGCUGGUGGCCCAGGCCAGGGAGGGAACCCUGGGCAGGGCUCUGGUGGGAGAGGGAGACAGAUGGAGGCAGUGGCUGGUGGGCCACUCUCUCCAGGUGCCCCUCAGCCAUGGGCCCUACAGUCCCCUCAGGGGACUCUAACCUGGGGGCCUGAGGUGCCAGGGUUCACAGACAGGGUUUCCCACCAGCCACACGCACCAGCUCUAUUUGGGGGAAGUGUAGUGAGGAGGAGCCCAGAGGACCCCAGGGGAGUGAGGAGGGAGAACUUGGAAGGGUGCAGCCCACUUCCAGACUCUCCCCUCUCCCACCCUUCUACCCUGUGAAGGGAAAUGAGGGCUUUAGUUUCCUGGGCAGGGAGGGGCAGCUUCUGAGGUUGCCAAAGGCCCCCACUGGAUGGAACCUGUUAGCUGCUCCUCUCCGCAGCCAGAAAUGCUGCCGGCUGCACCCAGAGGGAGCAGUGAGGCAGGACAGAUGGACAGGUUCCUCCUGCGCUGUAAUUCCCUGCUCCCUGGAGACUGGGAAAAGGCCGCAGGGCAGGGGGACUGGGCGGUGGUGGCUGGUGGUUUAAAGGUUGAACUUUCUCUGAAGCUCCUUUCCCCUUGCUCUUGGUCCCUGCCCCGCAAGCAAACCUGCCCCCUCUGCCUCCCAGUGCACCCAAUGACCCCCUCCCUUGGGGCGACUCCUGAUGAAGCACAACUCCCCGCAGGGCCCCCAGCCCACAGGGGUGGCCAUAUUUGGGCAGUUCCCAGUCCUGUGGGCUCGGCUAUCUGGGGAGCAGAUUUUGGGUCUGGAUCUCCCUGGGGAGUGGGUCCUGGGCUUGGAUCUUUCCCUAGGGGGCCCUCUUACUCCUUCCUCUCUCCUCCUCCUUCCCCAUUGCUGUAAAUAUUUCAACGAAAUGGAAAAGAAAAAAAAAAGACAAAAAAAAAAAAAAAGAAAAGAAAAAAAAUCUCAUCACUUGAAGCCACCGGGAGCCUGCGGCCCGGGCCAGCCCGGGCUUUCUCCGGAGCAGAGCAGCGCUGCUGGCCUGGCAGCCAGGACUUCUCCGUGUACGUGCAUCCCCAGUCCCCGCCGGGGCGGGCGGGCCGCCAGAGCAGCUUUUUACAAUCCAGAGACAGAAAACAAAAUCUAGAUGCAACAGCGAAACAAAGAACCCAUUUCCUUCCUGGCACCCUCCUUUCCUGCUCCGCCUGCCCGGCAUCAUCAGCCCUUCUGGGGCGUGUACCUCUCACUGCCUGCCCCAGGACCAGAGGCCUGUCUCCCCCUUCCCUCCCCACCGGCCCGGGGGAGACCUCUUCACACCCAAAGAUGCUUUGUCAAGAUGGCUGCGCUGUCCCUUUGAGUUCCUGCUUCUUGUAUAUUGCUCUGGGGACUCUCGCCGGGGAAGAUGGGGCUGAUUUCCCACCUAGAGAGGUUGAUGGCAGAAGGAAAAUGGGGAGGCACUGGGGUUGUGGAGGGCAUGGGUAUGGCUGAGGAGGGUGCUGGGAACGGCAAGGCGGUCUGGGGGAUGGGGAGGGGCAAAGGUGAGAGAUCACCUUCCCUAUCCUCCACCUUCCCGCAGGGAAGACGAAGCCAGGUGCCAGGGCUGGGGUCGGGACACCCAUGUUCUGGGCGGCUUGACCCCAAAUCCCAGACCCCGGAAGCUCCAGGCUCGGGAUGUGUCCUGAGCACCUGUCCCGGCCCCCUCCUCUCCAGCCUGUCAGGCCAGCCUCCCCAGCCCCCUUCCCUCAACUCUAGGGGCAGCAUAGCCCCAGGCCACCCUAGCCCAGCCCCUGCAUUGCCGUUUCCCCAGAGGUGGCCCCUCCACCUCUGCUCUGACCUCUCCCCAUCUCUCUGCCCCUCCUUUUCUCACAAGUGCCAUGAGUUUUCAAACAUCUUCGGGUCUCAGCCUGCUGCUGCCAUGAACUUUGUUGGGUUAAGGGGGAGGGGCUCUAGGAAGGAACUGGGGGGAAGGGGACAGGUAGGUGGCUGGAGGGACCCUUUUUGCUGCUAGAAAGCCCCUCCCUUCUCCCGGGGAGCUGGGGCUGGCUUGUCCCCAUCAAUUAGGGGAGAAGGGGUCAGACCAAAGAUGGUGGUUUGUCCCGUGUAAGGGAACAGGUGUGGGGAAGAGGUGGGGUUGGGUUCCAACUCUGGCUUUUUCUGGUAGAAAGGCCUAACCCAUUACACCAGAAGACCAUGGGUGAAGUCUAGAUGGGGAGGAGAAGUGAGGCCAGGGACAGUCUUGCCAGACGACUCUGAGGAGGGCAAGGGACAGUUCCAUGGCCCUUCCCGGACUGCACUAGGCUGGGAGCUCUGUUGUGUGGAGGGGUGGUCAGAGGUCUGUGAAGAGCGGGCAGGAGGCAUGAGCAGGCGAGGAGCUGGCCUGUCCCGGGAAGCAGCCCAGCCUGUGGCUGCCCCCGACACCAGGAGGAGGGCCAGGAGAGUUCCAGGGGGCUGAGGCACACAGAGAGGCCAACUUCCUCCCUGCCCAGCCUUCCUUGUAUCUCUCCAGACUCGGACAAUCAAAGGGAGAGAGGGUGUAUCGGGUCCUGUUCCAGCCGGCAUCGCCGGGUGGCUUCCAGGCCUCAGAGCUGUGUGGCAGGGCCCCCUGCUGGGGCUGGACAUCACUGCAGUCCAGUGCAAAGCCGCCCCCAGAGCCCAGGUGUCCCCCCAACCUAACCAGACCUGGUGCCUUGACGCCCCCACCCCAGCUGGGACGGUACAGAGAAGGGUCUUGGUUUCCUCUCCUACUCCCUUCCUUAGGCUCCUGAACUCGUUUGCUCCUAAAUCUUGUUAAUUCUUUUUCUCUGGAUUUUGGUUUCUUUUGGCUUUCCCUUGCCUUCCCCUUUCUCUGUCUCCAACACUCUUUCCCCAUGUCUUUCUGGCUGUCUCUAUGUUCCUCUUCUCUUAUCCUCAACUUUCUGUCCAUUCGGGCCUCCUCCCCACCUCCCACGCCCCAGCCCCUCCCUCCUUGGUCUCCUUUUCGAUAUGCCAAACCAAUUUUGGGUCGAGUGCAUUUAACGAGAACAAAACAAAAGGCUCAUAACAACAAGAACGUUUCAGAAAAAAACAAAAAGUUUUAAAAAAAUUGUUGAGUCAAAAAGUCAAACAAUAAAGAAAUUAAGAUUUCUUGGAA-3'- Poly-A tail
  • Coding region
NCBI Matured mRNA sequence viewer
;
More about the NCBI sViewer.
DNA
DNA (Gene ID: 22859)
ADGRL1
adhesion G protein-coupled receptor L1
NC_000019.10
19  14150873.. 14183602
14150873.. 14183602
strand -
CCDS32928.1
MGI:1929461
ClinVar, dbVar
ENSG00000072071
KIAA0821, CIRL1, LEC2
INSDC: AB020628
20973
616416
OTTHUMG00000182138
ENA, DDBJ, Monarch
NCBI CDS Gene viewer
More about the NCBI sViewer.
NCBI CDS gene sequence (4425 bp)
5'-ATGGCCCGCCTAGCCGCAGTGCTCTGGAATCTGTGTGTCACCGCCGTCCTGGTCACCTCGGCCACCCAAGGCCTGAGCCGGGCCGGGCTCCCGTTCGGGCTGATGCGCCGGGAGCTGGCGTGTGAAGGCTACCCCATCGAGCTGCGGTGCCCCGGCAGCGACGTCATCATGGTGGAGAATGCCAACTACGGGCGCACGGACGACAAGATTTGCGATGCTGACCCTTTCCAGATGGAGAATGTGCAGTGCTACCTGCCGGACGCCTTCAAGATCATGTCACAGAGGTGTAACAACCGCACCCAGTGCGTGGTGGTCGCCGGCTCGGATGCCTTTCCTGACCCCTGTCCTGGGACCTACAAGTACCTGGAGGTGCAGTACGACTGTGTCCCCTACAAAGTGGAGCAGAAAGTCTTCGTGTGCCCAGGGACCCTGCAGAAGGTGCTGGAGCCCACCTCGACACACGAGTCAGAGCACCAGTCTGGCGCATGGTGCAAGGACCCGCTGCAGGCGGGTGACCGCATCTACGTGATGCCCTGGATCCCCTACCGCACGGACACACTGACTGAGTATGCCTCGTGGGAGGACTACGTGGCCGCCCGCCACACCACCACCTACCGCCTGCCCAACCGCGTGGATGGCACAGGCTTTGTGGTCTACGATGGTGCCGTCTTCTACAACAAGGAGCGCACGCGCAACATCGTCAAGTATGACCTACGGACGCGCATCAAGAGCGGGGAGACGGTCATCAATACCGCCAACTACCATGACACCTCGCCCTACCGCTGGGGCGGAAAGACCGACATTGACCTGGCGGTGGACGAGAACGGGCTGTGGGTCATCTACGCCACTGAGGGCAACAACGGGCGGCTGGTGGTGAGCCAGCTGAACCCCTACACACTGCGCTTTGAGGGCACGTGGGAGACGGGTTACGACAAGCGCTCGGCATCCAACGCCTTCATGGTGTGTGGGGTCCTGTACGTCCTGCGTTCCGTGTACGTGGATGATGACAGCGAGGCGGCTGGCAACCGCGTGGACTATGCCTTCAACACCAATGCCAACCGCGAGGAGCCTGTCAGCCTCACCTTCCCCAACCCCTACCAGTTCATCTCCTCCGTTGACTACAACCCTCGCGACAACCAGCTGTACGTCTGGAACAACTATTTCGTGGTGCGCTACAGCCTGGAGTTCGGGCCGCCCGACCCCAGTGCTGGCCCAGCCACTTCCCCACCCCTCAGCACGACCACCACAGCCAGGCCCACGCCCCTCACCAGCACAGCCTCGCCCGCAGCCACCACCCCGCTCCGCCGGGCACCCCTCACCACGCACCCAGTGGGTGCCATCAACCAGCTGGGACCTGATCTGCCTCCAGCCACAGCCCCAGTCCCCAGCACCCGGCGGCCCCCAGCCCCGAATCTACACGTGTCCCCTGAGCTCTTCTGCGAGCCCCGAGAGGTACGGCGGGTCCAGTGGCCGGCCACCCAGCAGGGCATGCTGGTGGAGAGGCCCTGCCCCAAGGGGACTCGAGGAATTGCCTCCTTCCAGTGTCTACCAGCCTTGGGGCTCTGGAACCCCCGGGGCCCTGACCTCAGCAACTGCACCTCCCCCTGGGTCAACCAGGTGGCCCAGAAGATCAAGAGTGGGGAGAACGCGGCCAACATCGCCAGCGAGCTGGCCCGACACACCCGGGGCTCCATCTACGCGGGGGACGTCTCCTCCTCTGTGAAGCTGATGGAGCAGCTGCTGGACATCCTGGATGCCCAGCTGCAGGCCCTGCGGCCCATCGAGCGCGAGTCAGCCGGCAAGAACTACAACAAGATGCACAAGCGAGAGAGAACTTGTAAGGATTATATCAAGGCCGTGGTGGAGACAGTGGACAATCTGCTCCGGCCAGAAGCTCTGGAGTCCTGGAAGGACATGAATGCCACGGAGCAGGTGCACACGGCCACCATGCTCCTCGACGTCCTGGAGGAGGGCGCCTTCCTGCTGGCCGACAATGTCAGGGAGCCTGCCCGCTTCCTGGCTGCCAAGGAGAACGTGGTCCTGGAGGTCACAGTCCTGAACACAGAGGGCCAGGTGCAGGAGCTGGTGTTCCCCCAGGAGGAGTACCCGAGAAAGAACTCCATCCAGCTGTCTGCCAAAACCATCAAGCAGAACAGCCGCAATGGGGTGGTCAAAGTTGTCTTCATCCTCTACAACAACCTGGGCCTCTTCCTGTCCACGGAGAATGCCACAGTGAAGCTGGCCGGCGAAGCAGGCCCGGGTGGCCCTGGGGGCGCCTCTCTAGTGGTGAACTCACAGGTCATCGCAGCATCCATCAACAAGGAGTCCAGCCGCGTCTTCCTCATGGACCCTGTCATCTTCACCGTGGCCCACCTGGAGGACAAGAACCACTTCAATGCTAACTGCTCCTTCTGGAACTACTCGGAGCGTTCCATGCTGGGCTACTGGTCGACCCAAGGCTGCCGCCTGGTGGAGTCCAACAAGACCCATACCACGTGTGCCTGCAGCCACCTCACCAACTTCGCTGTGCTCATGGCTCACCGTGAGATCTACCAGGGCCGCATCAACGAGCTGCTGCTGTCGGTCATCACCTGGGTGGGCATTGTGATCTCCCTGGTCTGCTTGGCCATCTGCATCTCCACCTTCTGCTTCCTGCGGGGGCTGCAGACCGACCGCAACACCATCCACAAGAACCTGTGCATCAACCTCTTCCTGGCTGAGCTGCTCTTCCTGGTCGGGATCGACAAGACTCAGTATGAGATTGCCTGCCCCATCTTCGCCGGCCTGCTGCACTATTTCTTCCTGGCTGCCTTCTCCTGGCTGTGCCTGGAGGGCGTGCACCTCTACCTGCTACTAGTGGAGGTGTTTGAGAGCGAGTATTCCCGCACCAAGTACTACTACCTGGGTGGCTACTGCTTCCCGGCCCTGGTGGTGGGCATCGCGGCTGCCATTGACTACCGCAGCTACGGCACCGAGAAGGCCTGCTGGCTCCGAGTGGACAATTACTTCATCTGGAGTTTCATCGGGCCAGTCTCCTTCGTTATCGTGGTCAACCTGGTGTTCCTCATGGTGACCCTGCACAAGATGATCCGAAGCTCATCTGTGCTCAAGCCCGACTCCAGCCGCCTGGACAACATTAAATCCTGGGCGCTGGGGGCCATCGCGCTGCTGTTCCTGCTGGGCCTCACCTGGGCTTTCGGCCTCCTCTTCATCAACAAGGAGTCGGTGGTCATGGCCTATCTCTTCACCACCTTCAACGCCTTCCAGGGGGTCTTCATCTTCGTCTTTCACTGCGCCTTACAGAAGAAGGTGCACAAGGAGTACAGCAAGTGCCTGCGTCACTCCTACTGCTGCATCCGCTCCCCACCCGGGGGCACTCACGGATCCCTCAAGACCTCAGCCATGCGAAGCAACACCCGCTACTACACAGGGACCCAGAGCCGAATTCGGAGGATGTGGAATGACACTGTGAGGAAACAGACGGAGTCCTCCTTCATGGCGGGTGACATCAACAGCACCCCCACCCTGAACCGAGGTACCATGGGGAACCACCTGCTGACCAACCCCGTGCTGCAGCCCCGTGGGGGCACCAGTCCCTACAACACCCTCATCGCCGAGTCAGTGGGCTTCAATCCCTCCTCGCCCCCTGTCTTCAACTCCCCAGGGAGCTACCGGGAACCCAAGCACCCCTTGGGAGGCCGGGAAGCCTGTGGCATGGACACCCTGCCCCTGAACGGCAACTTCAATAACAGTTACTCCTTGCGAAGTGGGGATTTCCCTCCCGGGGATGGGGGCCCTGAGCCGCCCCGAGGCCGGAACCTAGCCGATGCGGCGGCCTTTGAGAAGATGATCATCTCAGAGCTGGTGCACAACAACCTGCGGGGGAGCAGCAGCGCGGCCAAGGGCCCTCCACCGCCTGAGCCCCCTGTGCCACCTGTGCCAGGGGGCGGGGGCGAGGAAGAGGCGGGCGGGCCCGGGGGTGCTGACCGGGCCGAGATTGAACTTCTCTATAAGGCCCTGGAGGAGCCTCTGCTGCTGCCCCGGGCCCAGTCGGTGCTGTACCAGAGCGATCTGGACGAGTCGGAGAGCTGCACGGCCGAGGACGGCGCCACCAGCCGGCCCCTCTCCTCCCCTCCTGGCCGGGACTCCCTCTATGCCAGCGGGGCCAACCTGCGGGACTCACCCTCCTACCCGGACAGCAGCCCTGAGGGGCCCAGTGAGGCCCTGCCCCCACCCCCTCCCGCACCCCCCGGCCCCCCCGAAATCTACTACACCTCGCGCCCGCCAGCCCTGGTGGCCCGGAATCCCCTGCAGGGCTACTACCAGGTGCGGCGTCCTAGCCACGAGGGCTACCTGGCAGCCCCAGGCCTTGAGGGGCCAGGGCCCGATGGGGACGGGCAGATGCAGCTGGTCACCAGTCTCTGA-3'
NCBI CDS gene sequence with introns (location: 14150873.. 14183602) (32730 bp)Download
NCBI Gene Viewer (CDS + introns)
NCBI CDS gene sequence with introns, 5'UTR and 3'UTR (location: 14147743.. 14206169) (58427 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions)
NCBI gene sequence (location: [14147743.. 14206169 + 1000]) (59427 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions + 1000 dNTP to potentially reach the promotor)
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