Protein
Protein (NP_001161840)
CBM13-ppGalNAc-T16
Polypeptide N-acetylgalactosaminyltransferase 16 (EC 2.4.1.41) (Polypeptide GalNAc transferase 16) (GalNAc-T16) (Polypeptide GalNAc transferase-like protein 1) (GalNAc-T-like protein 1) (pp-GaNTase-like protein 1) (Polypeptide N-acetylgalactosaminyltransferase-like protein 1) (Protein-UDP acetylgalactosaminyltransferase-like protein 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1)
GALNT16
polypeptide N-acetylgalactosaminyltransferase 16
Undefined
Curated
Ricin-like
R-Type Lectins
b-trefoil
GalNAc / Mucin-type glycopeptide
NP_001161840
57452
Q8N428
ENSP00000402970.3
Q8N428
Undefined
10.1074/jbc.M111.273722
neXtProt, PFAM, InterPro
Protein sequence and protein families (fasta) (558 amino acids) Download
MRKIRANAIAILTVAWILGTFYYLWQDNRAHAASSGGRGAQRAGRRSEQLREDRTIPLIVTGTPSKGFDEKAYLSAKQLKAGEDPYRQHAFNQLESDKLSPDRPIRDTRHYSCPSVSYSSDLPATSVIITFHNEARSTLLRTVKSVLNRTPANLIQEIILVDDFSSDPEDCLLLTRIPKVKCLRNDRREGLIRSRVRGADVAAATVLTFLDSHCEVNTEWLPPMLQRVKEDHTRVVSPIIDVISLDNFAYLAASADLRGGFDWSLHFKWEQIPLEQKMTRTDPTRPIRTPVIAGGIFVIDKSWFNHLGKYDAQMDIWGGENFELSFRVWMCGGSLEIVPCSRVGHVFRKRHPYNFPEGNALTYIRNTKRTAEVWMDEYKQYYYEARPSAIGKAFGSVATRIEQRKKMNCKSFRWYLENVYPELTVPVKEALPGIIKQGVNCLESQGQNTAGDFLLGMGICRGSAKNPQPAQAWLFSDHLIQQQGKCLAATSTLMSSPGSPVILQMCNPREGKQKWRRKGSFIQHSVSGLCLETKPAQLVTSKCQADAQAQQWQLLPHT
No structure currently available in the PDB RCSB Databank.
Structural models
AlphaFold v2: AF-Q8N428-F1Download
  Model Confidence:
  •    Very high (pLDDT > 90)
  •    Confident (90 > pLDDT > 70)
  •    Low (70 > pLDDT > 50)
  •    Very low (pLDDT < 50)

  AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

SWISS-MODEL structural models
SWISS-MODEL structural model
Modeller structural model (Homology modelling pipeline), Error: [1.4, 1.74] ÅDownload
The location of the lectin domain structural model is: 217-555
We infer [1.4, 1.74] Å as the interval of error of this structural model.
Template: 1XHB chain: A, O08912, NP_001153876.1, sequence identity: 39.5%, coverage: 96.8%, location in sequence: 95-553, (95-553 in PDB).
Show the alignment used for the construction of the structural model, Download.
Show the plot of DOPE energy score, Download.
Ligand
Glycan ligands from structural data
No crystal structures of complexes with glycan ligand.
Expression
Human Protein Atlas
GeneCards
mRNA expression in normal human tissues for GALNT16 Gene
ProteomicsDB
References
NCBI References (2 PubMed Identifiers)
  • Evaluation of GALNT16 polymorphisms to breast cancer risk in Chinese population. [31286696]
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases: completion of the family tree. [22186971]
UniProt Main References (3 PubMed Identifiers)
  • Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. [10574461]
  • Complete sequencing and characterization of 21,243 full-length human cDNAs. [14702039]
  • The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). [15489334]
RNA
RNA (Transcript ID: NM_001168368.2)
NM_001168368.2
polypeptide N-acetylgalactosaminyltransferase 16, transcript variant 1
All isoforms of GALNT16 containing a lectin domain
ENST00000448469.8
134..1810 (or 69260291.. 69352168)
69260158.. 69354466
NCBI Matured mRNA sequence 4108 NTPDownload 
m7G-5')ppp(5'-CUCCUUUUUCUGCUCUGCAGGACUGAGCAGCUAGGCGCGAGCGAAAACAAACAGCUGGGGCUGCGAGCGCCCCCGCCCCGGCCCCGAGAGCACGCCGGCCCAGUCCCCCACCUGGGGCGCCCGUCUGCCCACCAUGAGGAAGAUCCGCGCCAAUGCCAUCGCCAUCCUGACCGUAGCCUGGAUCCUGGGCACUUUCUACUACUUAUGGCAGGACAACCGAGCCCACGCAGCAUCCUCCGGCGGCCGGGGCGCGCAGAGGGCAGGCAGGAGGUCGGAGCAGCUCCGCGAGGACCGCACCAUCCCGCUCAUUGUGACAGGAACUCCCUCGAAAGGCUUUGAUGAGAAGGCCUACCUGUCGGCCAAGCAGCUGAAGGCUGGAGAGGACCCCUACAGACAGCACGCCUUCAACCAGCUGGAGAGUGACAAGCUGAGCCCAGACCGGCCCAUCCGGGACACCCGCCAUUACAGCUGCCCAUCUGUGUCCUACUCCUCGGACCUGCCAGCCACCAGCGUCAUCAUCACCUUCCACAAUGAGGCCCGUUCCACCCUGCUGCGCACAGUGAAGAGUGUCCUGAACCGAACUCCUGCCAACUUGAUCCAGGAGAUCAUUUUAGUGGAUGACUUCAGCUCAGAUCCGGAAGACUGUCUACUCCUGACCAGGAUCCCCAAGGUCAAGUGCCUGCGCAAUGAUCGGCGGGAAGGGCUGAUCCGGUCCCGAGUGCGUGGGGCGGACGUGGCUGCAGCUACCGUUCUCACCUUUCUGGAUAGCCACUGCGAAGUGAACACCGAGUGGCUGCCGCCCAUGCUGCAGCGGGUGAAGGAGGACCACACCCGCGUGGUGAGUCCCAUCAUUGAUGUCAUCAGUCUGGAUAAUUUUGCCUACCUUGCAGCAUCUGCUGACCUUCGUGGAGGGUUCGACUGGAGCCUGCAUUUCAAGUGGGAGCAGAUCCCUCUUGAGCAGAAGAUGACCCGGACAGACCCCACCAGGCCCAUAAGGACGCCUGUCAUAGCUGGAGGAAUCUUCGUGAUCGACAAGUCCUGGUUUAACCACUUGGGAAAGUAUGAUGCCCAGAUGGACAUCUGGGGGGGAGAGAAUUUUGAGCUCUCCUUCAGGGUGUGGAUGUGUGGUGGCAGUCUGGAGAUCGUCCCCUGCAGCCGGGUGGGCCAUGUCUUCAGGAAACGGCACCCCUACAACUUCCCUGAGGGUAAUGCCCUCACCUACAUCAGGAAUACUAAGCGCACUGCAGAAGUGUGGAUGGAUGAAUACAAGCAAUACUACUAUGAGGCCCGGCCCUCGGCCAUCGGGAAGGCCUUCGGCAGUGUGGCUACGCGGAUAGAGCAGAGGAAGAAGAUGAACUGCAAGUCCUUCCGCUGGUACCUGGAGAACGUCUACCCAGAGCUCACGGUCCCCGUGAAGGAAGCACUCCCCGGCAUCAUUAAGCAGGGGGUGAACUGCUUAGAAUCUCAGGGCCAGAACACAGCUGGUGACUUCCUGCUUGGAAUGGGGAUCUGCAGAGGGUCUGCCAAGAACCCGCAGCCCGCCCAGGCAUGGCUGUUCAGUGACCACCUCAUCCAGCAGCAGGGGAAGUGCCUGGCUGCCACCUCCACCUUAAUGUCCUCCCCUGGAUCCCCAGUCAUACUGCAGAUGUGCAACCCUAGAGAAGGCAAGCAGAAAUGGAGGAGAAAAGGAUCUUUCAUCCAGCAUUCAGUCAGUGGCCUCUGCCUGGAGACAAAGCCUGCCCAGCUGGUGACCAGCAAGUGUCAGGCUGACGCCCAGGCCCAGCAGUGGCAGCUGUUGCCACACACAUGACGGUAGCCCUGGGGCCUCCUGUACCUUUUGCAUGAGACUUCGGGACCGGAAGGGGGUUAGGGUGGGGGAGUGCAAAGUGGGCUGUUCCCAUCUCCUCACAUUUCUGCCAGGACCAUCAGCAAAUACCCACCAUGACACACGUUCUCCAAAGCUUGUUCUAGGAGGGCGCAGGCGGGCACGCCCCGAUGCCCUCAGUGCUGUCCUGGCCUUGCCCCGGGAGAGGAGAUGGUCAGGGUGCUGGACUGUUGCUGGGUAGAGACUGAGUAGGUGCCCCUGGCCCUUUGUCCUCUCCCUUGGCGCUUCUUGGGGCUGGGACAAUAGUGUGUGGUCUCUCCCUUGUUGCCCGGAGAAAGCAAGGACAGAAGCCCACACAGGGGUCUUUUGGGUCAUGAGGCCCAGCUGUGCAGGCAGGCAGGGCCAGGGGAAAUUGGGCAGCAUGGAUGGAGAGGCUGAAGGCUGGGAAGAGGGAAGGGGAGAGGGGCAGCCUGCAGGGGUAGCUGAAGAACAGGAAGGAGGUGAGAAGCCCGGUGACCUGUCAGAGAUGCCAAGCCCAGGGUGGCACUGGGUUGGGUGGGGACGGAUGGUGUCUUGGCAGCAAAGGAUGGGUAAUUUGCAAAUGAACAUGGAUAGAAGAGCAGCAAAGCACCAAAAGAACAAGGUCUCUUACCCAGGACACAGUCCCUUCCACACUUUACCAGCCCCAGGGUCUGAGCCCGACGCUGCCUCUUCCGGUCCUGUGCCUGUGGGUGCCCACAUUCUUAGCAAGAGGCUGCAGAGGGAUCUUUAGGGGAAGAUUCGGGCGUAGUUUAUUAAACAGACUCCACUUCUAUUUGGCCAUGUGUCAGGCUGAGACCUCUCUCUCGGGCAUUAAUGAACAGCUAGUGCCCUGUCCCUGCCGCCAGGACCCACUGAAAGGACGGGUAGCCACACACAUCCCUGAGUAGUCCCAGCCUCAUUUGUCAUUUUUGACUCCUGCUUUCUCAAAGGUUUUUGCCUCUGUCAAUACAGCAUCAUGGGUGGUUGGAAAGAAGGGAACUUCCCUUCUGGACCAAGAACAGCCCCUAAGUCAUUAGGGUUCAACCUCACCCUUAUUCCCCUCCCCGCUACAGGAGCCCCUAAGUCAUUAGGGCUCAACCUCACCCUUAUUCCCCUCCCUACUACAGGAGGGAUUUUCUUGAAGGGUCAGCUAUUGCACUGUGCUGGGAGGCUGGCUGUGGCUCCUGUUUGUGAAGAGAACUCCCAGUUCCUUUUCACAGCCGCUGAGAACACAUCCACACAUCUACCCCACGGCCUUGUCUUGGAACUGCUCCUGCUAUCCCCACACCCUGCUUCCUCACCCCACUGGCUCUUGGGCAAAUGACUGUUGGUACCAGGACCCUGGGGGUCUCCCCUACAAAGCAGACCAGCCUGGGGCAGAUAUACCUACCACAGGAGCCCCCUGUCUUUCAUAGGCCAAGGAUCCACAUACCCAUAGAGUUCAUGGAUUCUAGAGGGUCUAGGAAUCUCUUGAAAUUGUCCCUAAAAUACUGCAUGUGUGUGCAUACAUGCAUUUUCCUGGGGAAAAAGUCCAUGGCUUCUAAAAGAGGUCCCUGAUCCCCAAAGGGCCUGAACCUCUGCUCUGGAUUGAAGCCACUGUCUGCCCAAGCUGCCACCCCCUAAUCUUCCUCCCUGGCGUGCUCAAACUGCCAUCGCCUGCUCCCUCCACACGGCCCUUGGGGUCAGCAGCCAAGUGUCUGUGGUCCGCAGCACCUGCUCUGGAGGGCUCUCCAGCAGUUUCGCCUCCUGACUCUCACCAGCGUCCUCUCGGCAGCACUCCCGUGCCCAAGUGCACCCCUCUGGACUUGCCAGCGCAGGCCCCUUCGCUCCCAGGGCCAUGCUUUGCCUGUCCUCUGUCGUGAUGUUUCUUCCGCAGCCAGGUGCAGCCUCAGAUCCCCUGUUCAUCUGGGAAGCCUCCUGCCACAGCUUAGGACAGAACUGGGCCCAGGGCAAAGGCCUCUCCCCAGAGGAUGGACUAGAAGGCCUGGGCCACACUCGGGCAUGGACCUUUGGGGCUGGGGAGCCGGGGCUGCGCCUGUUGAAUGUAAGAGGACUGCUGACCAGAGGGCCUUCAAGAGGGUCUCUCUGUCCUUUGCUGUGGUCAGAUCAGGCUCUGCACUUAUCAGCCGGUCCUUUGUGGCAACGCAGCCCUGUUCUGUUUUUGCUUUUCCUCUUCUUGACCAAAGCAUGUGCCACUAGCUGUCCUUGAGGACCUCGUCUUUAUGAAACACACACCUGGAAUAAAACCACUUCUUACAUGUC-3'- Poly-A tail
  • Coding region
NCBI Matured mRNA sequence viewer
;
More about the NCBI sViewer.
DNA
DNA (Gene ID: 57452)
GALNT16
polypeptide N-acetylgalactosaminyltransferase 16
NC_000014.9
14  69260291.. 69352168
69260291.. 69352168
strand +
CCDS32107.1
MGI:1917754
ClinVar, dbVar
ENSG00000100626
KIAA1130, GalNAc-T16
uc001xlb.3
INSDC: AB032956
23233
615132
OTTHUMG00000171231
ENA, DDBJ, Monarch
NCBI CDS Gene viewer
More about the NCBI sViewer.
NCBI CDS gene sequence (1677 bp)
5'-ATGAGGAAGATCCGCGCCAATGCCATCGCCATCCTGACCGTAGCCTGGATCCTGGGCACTTTCTACTACTTATGGCAGGACAACCGAGCCCACGCAGCATCCTCCGGCGGCCGGGGCGCGCAGAGGGCAGGCAGGAGGTCGGAGCAGCTCCGCGAGGACCGCACCATCCCGCTCATTGTGACAGGAACTCCCTCGAAAGGCTTTGATGAGAAGGCCTACCTGTCGGCCAAGCAGCTGAAGGCTGGAGAGGACCCCTACAGACAGCACGCCTTCAACCAGCTGGAGAGTGACAAGCTGAGCCCAGACCGGCCCATCCGGGACACCCGCCATTACAGCTGCCCATCTGTGTCCTACTCCTCGGACCTGCCAGCCACCAGCGTCATCATCACCTTCCACAATGAGGCCCGTTCCACCCTGCTGCGCACAGTGAAGAGTGTCCTGAACCGAACTCCTGCCAACTTGATCCAGGAGATCATTTTAGTGGATGACTTCAGCTCAGATCCGGAAGACTGTCTACTCCTGACCAGGATCCCCAAGGTCAAGTGCCTGCGCAATGATCGGCGGGAAGGGCTGATCCGGTCCCGAGTGCGTGGGGCGGACGTGGCTGCAGCTACCGTTCTCACCTTTCTGGATAGCCACTGCGAAGTGAACACCGAGTGGCTGCCGCCCATGCTGCAGCGGGTGAAGGAGGACCACACCCGCGTGGTGAGTCCCATCATTGATGTCATCAGTCTGGATAATTTTGCCTACCTTGCAGCATCTGCTGACCTTCGTGGAGGGTTCGACTGGAGCCTGCATTTCAAGTGGGAGCAGATCCCTCTTGAGCAGAAGATGACCCGGACAGACCCCACCAGGCCCATAAGGACGCCTGTCATAGCTGGAGGAATCTTCGTGATCGACAAGTCCTGGTTTAACCACTTGGGAAAGTATGATGCCCAGATGGACATCTGGGGGGGAGAGAATTTTGAGCTCTCCTTCAGGGTGTGGATGTGTGGTGGCAGTCTGGAGATCGTCCCCTGCAGCCGGGTGGGCCATGTCTTCAGGAAACGGCACCCCTACAACTTCCCTGAGGGTAATGCCCTCACCTACATCAGGAATACTAAGCGCACTGCAGAAGTGTGGATGGATGAATACAAGCAATACTACTATGAGGCCCGGCCCTCGGCCATCGGGAAGGCCTTCGGCAGTGTGGCTACGCGGATAGAGCAGAGGAAGAAGATGAACTGCAAGTCCTTCCGCTGGTACCTGGAGAACGTCTACCCAGAGCTCACGGTCCCCGTGAAGGAAGCACTCCCCGGCATCATTAAGCAGGGGGTGAACTGCTTAGAATCTCAGGGCCAGAACACAGCTGGTGACTTCCTGCTTGGAATGGGGATCTGCAGAGGGTCTGCCAAGAACCCGCAGCCCGCCCAGGCATGGCTGTTCAGTGACCACCTCATCCAGCAGCAGGGGAAGTGCCTGGCTGCCACCTCCACCTTAATGTCCTCCCCTGGATCCCCAGTCATACTGCAGATGTGCAACCCTAGAGAAGGCAAGCAGAAATGGAGGAGAAAAGGATCTTTCATCCAGCATTCAGTCAGTGGCCTCTGCCTGGAGACAAAGCCTGCCCAGCTGGTGACCAGCAAGTGTCAGGCTGACGCCCAGGCCCAGCAGTGGCAGCTGTTGCCACACACATGA-3'
NCBI CDS gene sequence with introns (location: 69260291.. 69352168) (91878 bp)Download
NCBI Gene Viewer (CDS + introns)
NCBI CDS gene sequence with introns, 5'UTR and 3'UTR (location: 69260158.. 69354466) (94309 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions)
NCBI gene sequence (location: [69260158 - 1000].. 69354466) (95309 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions + 1000 dNTP to potentially reach the promotor)
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