NCBI Summary
This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Protein
Protein (NP_001073980)
C-type lectin domain family 2 member L
C-type lectin domain family 2 member L
CLEC2L
C-type lectin domain family 2 member L
Undefined
Very low evidence
C-type lectin
Undefined
C-type - Natural Killer NK
a/b mixed / C-type lectin-like
Uncharacterised
NP_001073980
154790
P0C7M8
ENSP00000390661.2
P0C7M8
0.285
10.1371/journal.pone.0065345
neXtProt, PFAM, InterPro
Protein sequence and protein families (fasta) (214 amino acids) Download
MEPAREPPSRARPPPPLAARPAPAPAAPRPRSPAEAEARGPEGLLRRSGSGYEGSTSWKAALEDTTTRLLLGAIAVLLFAILVVMSILASKGCIKCEAPCPEDWLLYGRKCYFFSEEPRDWNTGRQYCHTHEAVLAVIQSQKELEFMFKFTRREPWIGLRRVGDEFHWVNGDPFDPDTFTIAGPGECVFVEPTRLVSTECLMTRPWVCSKMAYT
No structure currently available in the PDB RCSB Databank.
Structural models
AlphaFold v2: AF-P0C7M8-F1Download
  Model Confidence:
  •    Very high (pLDDT > 90)
  •    Confident (90 > pLDDT > 70)
  •    Low (70 > pLDDT > 50)
  •    Very low (pLDDT < 50)

  AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

SWISS-MODEL structural models
SWISS-MODEL structural model
Modeller structural model (Homology modelling pipeline), Error: [1.51, 1.92] ÅDownload
The location of the lectin domain structural model is: 96-209
We infer [1.51, 1.92] Å as the interval of error of this structural model.
Template 1: 6PWS chain: A, E1BIQ4, XP_005198961.1, sequence identity: 31.6%, coverage: 99.1%, location in sequence: 174-302, (162-290 in PDB).
Template 2: 6JJJ chain: A, P70194, NP_058031.2, sequence identity: 28.9%, coverage: 99.1%, location in sequence: 393-543, (393-543 in PDB).
Template 3: 6LFJ chain: A, Q9D8Q7, NP_081494.1, sequence identity: 28.9%, coverage: 99.1%, location in sequence: 42-174, (75-207 in PDB).
Show the alignment used for the construction of the structural model, Download.
Show the plot of DOPE energy score, Download.
Ligand
Glycan ligands from structural data
No crystal structures of complexes with glycan ligand.
Expression
Human Protein Atlas
GeneCards
mRNA expression in normal human tissues for CLEC2L Gene
ProteomicsDB
References
NCBI References (1 PubMed Identifiers)
UniProt Main References (1 PubMed Identifiers)
All isoforms of this gene containing a lectin domain
NP_001340297.1, XP_016867259.1, NP_001073980.2
RNA
RNA (Transcript ID: NM_001080511.4)
NM_001080511.4
C-type lectin domain family 2 member L, transcript variant 1
All isoforms of CLEC2L containing a lectin domain
ENST00000422142.7
244..888 (or 139523928.. 139544342)
139523685.. 139544985
NCBI Matured mRNA sequence 1531 NTPDownload 
m7G-5')ppp(5'-AGCCCGGCUGUGCGUGGAGGCUGCGGCUCGGCGGGGCAGGCGCUGAGCGCACCGCGGCGGCACCCGGCGCAGAGGCUCCAGCGCGGGGAGCCGGGCUCAGCCCCGGCCUGCCAGCGCCGCGGUCCUAGCCCACCCGAGGCCGGCCUGGGGGGCCCGCAGGGCGCGCGGAGCGCCGAGUGCGCGUCGGGCUGGGCCCCGCACCCCGGUGCAGGAGCGCGGGCGCGGCGCGGCGGAGCGCCCCGCAUGGAGCCGGCCCGGGAGCCCCCCUCGCGGGCCCGGCCGCCGCCGCCCCUCGCCGCGCGCCCCGCGCCCGCCCCCGCCGCCCCCAGGCCGCGUUCGCCCGCAGAGGCUGAGGCCCGCGGCCCCGAGGGGCUGCUGCGGCGAUCCGGGUCGGGCUACGAGGGCAGCACCAGCUGGAAGGCGGCCUUGGAGGACACCACCACACGCCUCCUGCUGGGUGCCAUCGCGGUCCUUCUGUUCGCCAUCUUGGUGGUGAUGAGCAUCUUGGCUUCCAAGGGCUGCAUCAAGUGCGAAGCGCCCUGCCCGGAGGACUGGCUGCUCUACGGAAGGAAGUGCUACUUCUUUUCCGAGGAACCCAGAGACUGGAACACAGGCAGGCAGUACUGCCACACCCACGAGGCGGUGCUGGCUGUGAUUCAGAGCCAGAAGGAGCUGGAAUUUAUGUUCAAGUUCACGCGGAGGGAGCCCUGGAUUGGACUACGCAGAGUUGGGGACGAAUUCCACUGGGUCAACGGGGACCCGUUUGAUCCGGACACGUUCACCAUCGCAGGUCCAGGGGAGUGUGUCUUCGUGGAGCCCACCAGGCUGGUGUCGACGGAGUGUCUGAUGACCCGGCCCUGGGUGUGCAGCAAGAUGGCCUAUACUUGAGGUGGGUGGGGCCAGAGGUGGCCCCGCCCCUAGGCCUGUGGGAGGUGUCUGGUGUCUGCUCAAGACCUGCUUCCAGCGGAGCCGCCUGCCCUCUGCAAGGCGAAGCGGUGGGUGCGUGGCCUCCGCCCCAGGCCCCUCUCCCAGGCCCUGGCGCUCUGAGUCCCUGGUUCCUGGCCUCCUUUGUCUGCAGGCAGGUCGUGUGGCUCAGCAGUUAAAUCCCAUAUGCUAGGUAGUGUAGGCAUCUGCCCACCUACACACACACACAUGCAUAGGUACACGCACGCACAGACGCUGUCCCUUCUGAAGCUCAGUGUCCAUCCUGAGCCACCCCACAGAUCUCUCUCCGGCCCCCUAGAAGCCCUCUCCUCACUGCAGCCCUGGUGCUCUGGGGAAGGAGGGGCAUUGACAGGUGGUUUGACUGUUCACCCAGCAGCCCCGCUUCCCCACUGGUUUCUCUCCUGGCUGCCGGCGGAGGUAGGCUGGGAAAGCUUCCCCCUCACCUAGGCCGGGCCAGCCCCGCCCCGGGCCCCAGAGGUCCCCUGCAUCCCCCUUCUUUGCCUUGCCUGGGUUCUCAGGCAGGGCCCCUGCUGUGUCCGUGGUGCUGUUGUAUUGGUCACUAACGGAAUAAAGAGUUAAUAUCUCA-3'- Poly-A tail
  • Coding region
NCBI Matured mRNA sequence viewer
;
More about the NCBI sViewer.
DNA
DNA (Gene ID: 154790)
CLEC2L
C-type lectin domain family 2 member L
NC_000007.14
7  139523928.. 139544342
139523928.. 139544342
strand +
CCDS47724.1
MGI:2141402
ClinVar, dbVar
ENSG00000236279
FLJ32986
uc010lnd.4
INSDC: AK057548
21969
OTTHUMG00000164900
ENA, DDBJ, Monarch
NCBI CDS Gene viewer
More about the NCBI sViewer.
NCBI CDS gene sequence (645 bp)
5'-ATGGAGCCGGCCCGGGAGCCCCCCTCGCGGGCCCGGCCGCCGCCGCCCCTCGCCGCGCGCCCCGCGCCCGCCCCCGCCGCCCCCAGGCCGCGTTCGCCCGCAGAGGCTGAGGCCCGCGGCCCCGAGGGGCTGCTGCGGCGATCCGGGTCGGGCTACGAGGGCAGCACCAGCTGGAAGGCGGCCTTGGAGGACACCACCACACGCCTCCTGCTGGGTGCCATCGCGGTCCTTCTGTTCGCCATCTTGGTGGTGATGAGCATCTTGGCTTCCAAGGGCTGCATCAAGTGCGAAGCGCCCTGCCCGGAGGACTGGCTGCTCTACGGAAGGAAGTGCTACTTCTTTTCCGAGGAACCCAGAGACTGGAACACAGGCAGGCAGTACTGCCACACCCACGAGGCGGTGCTGGCTGTGATTCAGAGCCAGAAGGAGCTGGAATTTATGTTCAAGTTCACGCGGAGGGAGCCCTGGATTGGACTACGCAGAGTTGGGGACGAATTCCACTGGGTCAACGGGGACCCGTTTGATCCGGACACGTTCACCATCGCAGGTCCAGGGGAGTGTGTCTTCGTGGAGCCCACCAGGCTGGTGTCGACGGAGTGTCTGATGACCCGGCCCTGGGTGTGCAGCAAGATGGCCTATACTTGA-3'
NCBI CDS gene sequence with introns (location: 139523928.. 139544342) (20415 bp)Download
NCBI Gene Viewer (CDS + introns)
NCBI CDS gene sequence with introns, 5'UTR and 3'UTR (location: 139523685.. 139544985) (21301 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions)
NCBI gene sequence (location: [139523685 - 1000].. 139544985) (22301 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions + 1000 dNTP to potentially reach the promotor)
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