NCBI Summary
This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.
Protein
Protein (NP_473451)
CBM13-ppGalNAc-T15
Polypeptide N-acetylgalactosaminyltransferase 15 (EC 2.4.1.41) (Polypeptide GalNAc transferase-like protein 2) (GalNAc-T-like protein 2) (pp-GaNTase-like protein 2) (Polypeptide N-acetylgalactosaminyltransferase-like protein 2) (Protein-UDP acetylgalactosaminyltransferase-like protein 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2)
GALNT15
polypeptide N-acetylgalactosaminyltransferase 15
Undefined
Curated
Ricin-like
R-Type Lectins
b-trefoil
GalNAc / Mucin-type glycopeptide
NP_473451
117248
Q8N3T1
ENSP00000344260.5
Q8N3T1
Undefined
10.1074/jbc.M111.273722
neXtProt, PFAM, InterPro
Protein sequence and protein families (fasta) (639 amino acids) Download
MLLRKRYRHRPCRLQFLLLLLMLGCVLMMVAMLHPPHHTLHQTVTAQASKHSPEARYRLDFGESQDWVLEAEDEGEEYSPLEGLPPFISLREDQLLVAVALPQARRNQSQGRRGGSYRLIKQPRRQDKEAPKRDWGADEDGEVSEEEELTPFSLDPRGLQEALSARIPLQRALPEVRHPLCLQQHPQDSLPTASVILCFHDEAWSTLLRTVHSILDTVPRAFLKEIILVDDLSQQGQLKSALSEYVARLEGVKLLRSNKRLGAIRARMLGATRATGDVLVFMDAHCECHPGWLEPLLSRIAGDRSRVVSPVIDVIDWKTFQYYPSKDLQRGVLDWKLDFHWEPLPEHVRKALQSPISPIRSPVVPGEVVAMDRHYFQNTGAYDSLMSLRGGENLELSFKAWLCGGSVEILPCSRVGHIYQNQDSHSPLDQEATLRNRVRIAETWLGSFKETFYKHSPEAFSLSKAEKPDCMERLQLQRRLGCRTFHWFLANVYPELYPSEPRPSFSGKLHNTGLGLCADCQAEGDILGCPMVLAPCSDSRQQQYLQHTSRKEIHFGSPQHLCFAVRQEQVILQNCTEEGLAIHQQHWDFQENGMIVHILSGKCMEAVVQENNKDLYLRPCDGKARQQWRFDQINAVDER
No structure currently available in the PDB RCSB Databank.
Structural models
AlphaFold v2: AF-Q8N3T1-F1Download
  Model Confidence:
  •    Very high (pLDDT > 90)
  •    Confident (90 > pLDDT > 70)
  •    Low (70 > pLDDT > 50)
  •    Very low (pLDDT < 50)

  AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

SWISS-MODEL structural models
SWISS-MODEL structural model
Modeller structural model (Homology modelling pipeline), Error: [1.64, 2.16] ÅDownload
The location of the lectin domain structural model is: 504-631
We infer [1.64, 2.16] Å as the interval of error of this structural model.
Template: 1XHB chain: A, O08912, NP_001153876.1, sequence identity: 21.9%, coverage: 93.8%, location in sequence: 95-553, (95-553 in PDB).
Show the alignment used for the construction of the structural model, Download.
Show the plot of DOPE energy score, Download.
Ligand
Glycan ligands from structural data
No crystal structures of complexes with glycan ligand.
Expression
Human Protein Atlas
GeneCards
mRNA expression in normal human tissues for GALNT15 Gene
ProteomicsDB
References
NCBI References (6 PubMed Identifiers)
  • A reference map of the human binary protein interactome. [32296183]
  • Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. [20800603]
  • Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T15. [15147861]
  • The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. [12975309]
  • Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries. [11597177]
  • Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. [11256614]
UniProt Main References (4 PubMed Identifiers)
  • Complete sequencing and characterization of 21,243 full-length human cDNAs. [14702039]
  • The full-ORF clone resource of the German cDNA Consortium. [17974005]
  • The DNA sequence, annotation and analysis of human chromosome 3. [16641997]
  • The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). [15489334]
All isoforms of this gene containing a lectin domain
NP_001305981.1, XP_016861171.1, XP_016861172.1, NP_473451.3
RNA
RNA (Transcript ID: NM_054110.5)
NM_054110.5
polypeptide N-acetylgalactosaminyltransferase 15, transcript variant 1
All isoforms of GALNT15 containing a lectin domain
ENST00000339732.10
473..2392 (or 16175152.. 16227500)
16174680.. 16230165
NCBI Matured mRNA sequence 5057 NTPDownload 
m7G-5')ppp(5'-ACAUCUGUUGAUCUGACCUGACUGGAAGCGUCCAAAGAGGGACGGCUGUCAGCCCUGCUUGACUGAGAACCCACCAGCUCAUCCCAGACACCUCAUAGCAACCUAUUUAUACAAAGGGGGAAAGAAACACCUGAGCAGAAUGGAAUCAUUAUUUUUUUCCCAAGGAGAAAACCGGGGUAAAGGGAGGGAAGCAAUUCAAUUUGAAGUCCCUGUGAAUGGGCUUUCAGAAGGCAAUUAAAGAAAUCCACUCAGAGAGGACUUGGGGUGAAACUUGGGUCCUGUGGUUUUCUGAUUGUAAGUGGAAGCAGGUCUUGCACACGCUGUUGGCAAAUGUCAGGACCAGGUUAAGUGACUGGCAGAAAAACUUCCAGGUGGAACAAGCAACCCAGGUUCUGCUGCAAGCUUGAAGGAGCCUGGAGCGGGAGAAAGCUAACUUGAACAUGACCUGUUGCAUUUGGCAAGUUCUAGCAACAUGCUCCUAAGGAAGCGAUACAGGCACAGACCAUGCAGACUCCAGUUCCUCCUGCUGCUCCUGAUGCUGGGAUGCGUCCUGAUGAUGGUGGCGAUGUUGCACCCUCCCCACCACACCCUGCACCAGACUGUCACAGCCCAAGCCAGCAAGCACAGCCCUGAAGCCAGGUACCGCCUGGACUUUGGGGAAUCCCAGGAUUGGGUACUGGAAGCUGAGGAUGAGGGUGAAGAGUACAGCCCUCUGGAGGGCCUGCCACCCUUUAUCUCACUGCGGGAGGAUCAGCUGCUGGUGGCCGUGGCCUUACCCCAGGCCAGAAGGAACCAGAGCCAGGGCAGGAGAGGUGGGAGCUACCGCCUCAUCAAGCAGCCAAGGAGGCAGGAUAAGGAAGCCCCAAAGAGGGACUGGGGGGCUGAUGAGGACGGGGAGGUGUCUGAAGAAGAGGAGUUGACCCCGUUCAGCCUGGACCCACGUGGCCUCCAGGAGGCACUCAGUGCCCGCAUCCCCCUCCAGAGGGCUCUGCCCGAGGUGCGGCACCCACUGUGUCUGCAGCAGCACCCUCAGGACAGCCUGCCCACAGCCAGCGUCAUCCUCUGUUUCCAUGAUGAGGCCUGGUCCACUCUCCUGCGGACUGUACACAGCAUCCUCGACACAGUGCCCAGGGCCUUCCUGAAGGAGAUCAUCCUCGUGGACGACCUCAGCCAGCAAGGACAACUCAAGUCUGCUCUCAGCGAAUAUGUGGCCAGGCUGGAGGGGGUGAAGUUACUCAGGAGCAACAAGAGGCUGGGUGCCAUCAGGGCCCGGAUGCUGGGGGCCACCAGAGCCACCGGGGAUGUGCUCGUCUUCAUGGAUGCCCACUGCGAGUGCCACCCAGGCUGGCUGGAGCCCCUCCUCAGCAGAAUAGCUGGUGACAGGAGCCGAGUGGUAUCUCCGGUGAUAGAUGUGAUUGACUGGAAGACUUUCCAGUAUUACCCCUCAAAGGACCUGCAGCGUGGGGUGUUGGACUGGAAGCUGGAUUUCCACUGGGAACCUUUGCCAGAGCAUGUGAGGAAGGCCCUCCAGUCCCCCAUAAGCCCCAUCAGGAGCCCUGUGGUGCCCGGAGAGGUGGUGGCCAUGGACAGACAUUACUUCCAAAACACUGGAGCGUAUGACUCUCUUAUGUCGCUGCGAGGUGGUGAAAACCUCGAACUGUCUUUCAAGGCCUGGCUCUGUGGUGGCUCUGUUGAAAUCCUUCCCUGCUCUCGGGUAGGACACAUCUACCAAAAUCAGGAUUCCCAUUCCCCCCUCGACCAGGAGGCCACCCUGAGGAACAGGGUUCGCAUUGCUGAGACCUGGCUGGGGUCAUUCAAAGAAACCUUCUACAAGCAUAGCCCAGAGGCCUUCUCCUUGAGCAAGGCUGAGAAGCCAGACUGCAUGGAACGCUUGCAGCUGCAAAGGAGACUGGGUUGUCGGACAUUCCACUGGUUUCUGGCUAAUGUCUACCCUGAGCUGUACCCAUCUGAACCCAGGCCCAGUUUCUCUGGAAAGCUCCACAACACUGGACUUGGGCUCUGUGCAGACUGCCAGGCAGAAGGGGACAUCCUGGGCUGUCCCAUGGUGUUGGCUCCUUGCAGUGACAGCCGGCAGCAACAGUACCUGCAGCACACCAGCAGGAAGGAGAUUCACUUUGGCAGCCCACAGCACCUGUGCUUUGCUGUCAGGCAGGAGCAGGUGAUUCUUCAGAACUGCACGGAGGAAGGCCUGGCCAUCCACCAGCAGCACUGGGACUUCCAGGAGAAUGGGAUGAUUGUCCACAUUCUUUCUGGGAAAUGCAUGGAAGCUGUGGUGCAAGAAAACAAUAAAGAUUUGUACCUGCGUCCGUGUGAUGGAAAAGCCCGCCAGCAGUGGCGUUUUGACCAGAUCAAUGCUGUGGAUGAACGAUGAAUGUCAAUGUCAGAAGGAAAAGAGAAUUUUGGCCAUCAAAAUCCAGCUCCAAGUGAACUUAAAGAGCUUAUAUAUUUCAUGAAGCUGAUCCUUUUGUGUGUGUGCUCCUGGUGUUAGGAGAGAAAAAAGCUCUAUGAAAGAAUAUAGGAAGUUUCUCCUUUUCACACCUUAUUUCAUUGACUGCUGGCUGCUUUAAAAAAAAAAAAAAAGGAUCCAUUGUACCGUUGUCUUCAUCACUGGGAAAUGAUUAUUACAUAGUACAGAAGAUUCUUUGUUUUUCUCCACUGAGCACUUAACAAUUGCUUUCUCUCUGGCCUGGACAUUCUCUGGCAGCACCUCCAGGAUACAUAAAUUCAAUGGAUCAAUUUAUUUGUCUUCAAAUGGCCUUAACUUGGAUUGUCUGUUUGGCCAACCAUGAAAAUUAAAGAGUGAAGCAGAUGUAAUGGCCUGACAUUCCAAAAACUCUGAAUUGGGUUUAUUAGCACAAAUGUUGUGUUCAUUUGUUGAGCCAUAUCUCAGAAGAAGGAAAGGGAGCUACAGAAAGGAGGUUUAGGAUUGCAGAGAAGAUGCAAGAGCACUUUGGCCCAAUUCUCCAGCUCAACCCAGCAGCUGAAAAGCUUCAAGAGAUCUAGGAAAAGACAUUUUCAUGUUAAUGAGAAUUUCCACCAUUGUAGAGAAUUUCCUUCCUACUGAGAAUCUACCUCUAUUCCCCCUGCCCUAGCUCUUCUCUAACUUGGUUAACCAUAACCAUAACCAGAUUCCCUUGCAAUCGAUUUCUCUUUAGUCGUUGGUGUUAGAAGUACCAGCACAAUUUGAGCAUUCCCAUUAACAAAGGUGUUCACAGUUGAGAAACUCUCCUGCCGGGCGCGGUGGCUCAUGCCUGUAAUUCCAGCACUUUGGGAGGCAGAGUUGGGAGGAUCACCUGAUGUCAGGGGUUUGAGACCAGCCUGGUCAACAUUGCAAAACCUUGUCUCUACUAAAAAUACAAAAAUUAGCUGGGCAUGGUGGCGCAUACCUGUAAUCCCAGCUACUUGGGAGGCUGAGGCAAGAGAAUCGCUUGAACCCAGGAGGCAGAGGUUGCAGUGAGCUGAGAUCAUGCCAUUGCACUCCAACCUGGGUGACAGAGUGAGACUCCAUCUCAAAAAAAAAAAAAAAGAGAGAAACUCUCCUGAUGCCCUGUUACAGGGUUUGCACUGACUGGAGCAGAAACAGCAACCUUUCUAAAAAAGCAAACCUUUUUCCUGGGAGGAAAAUGCCAGAGCCUGAGCCAAAAUUCUUAUGACAGGUAACAUUUGGGUGUUAAUGUCCAUGAGAGCUGACAGGGCCAUCUCUGAGCCCAUAUAACUGUCUGGAACCCCCAAAUGUGUCCACAGGUUGAAUGUCCAUGAGUGUGGGAAGAACACGGCUCAUCUGGAGCACAGCUGAGGCUAGUAAGAGCUAAAUGACUUUCCUUGCUAUGACUUGGCUUACCUGAAUUAGCUGUAAGAGUUGCCGAAUGGGAUGGGUUCUGCUAUUUAAUAAACAGCAUUCAUAUUCAUUUUUCCCCAGAUGGAGUUACCUACCUUUCCACAUGGUCAGCUUAGAAAUCUUCCCCUAAAGAUGCUAAUCUCCUUUGGGCUGUCUCAGAACACAGUAUCCUUCAAAUAAGAAAAACUGAGUGGGAAGUGCAGUGUUUCCAAACAAUACCUAUCAUAACUACGUAUUCAUUGUCUACCUGCUAAGUCAAGGGUUCACUGCAUUUCUCCUUCCUCAGAAUACACUCUGGACCUGUGCUGUCUAAUAUGGUAGCCACUAACAAAAUGUGGCCAUUUUGAUGGAAAUCCAUUAAAAUCAAAGAAAAUUUAAAACUCAAUUCCUCAAUUGGGCUGGCCACAUUUCAAAUGCUCACUACCCACCUGUGGCUAGGGUCUACUUCUACUGUAUUGGCGAGCAUGGAUAUAGAACAUUUCAUCACAGUUCUGUUGGACCAAUCUAGAUAGAUUCAUUAUCCCAUCUAGAGAAGAGACUUUAGUCACUGUCUUCUUGCUUCAGACCCAUCUAUAUUUAAAACAAAUUUCCCUAAAUCCUGAGACUGAGACGGAGCUACAAAUUCUCAGAUGGCGACCGUGUAAAUGGUAUUAGCGGCUGAAGAAAAAAAAUUUUUCAAGACCUCUGUUUUUUAACUGAACUUUAUCAUUGGCAUUGUGGGUCUUUGAAGUUGCUGGGAUAAAUUAAUAUAAUUAAAUAAAAGACUGAAUUUAAUUGCAUAAAUUGUAUUAGGUGGCAAUUAACAAAAGGACCCAGAUGGCUUAUUGCCUAAUUGGGUGAACAAAGCAAGAAUAUGGUGUUUCUUGCUUCCUUAACCAGCUCCAUGAUUUAUUACUUUAUUGCAGAAGUGGCUGUCAACUCAGUCCCUGGCUGGUAUUUACAGACCCUUAAUUUAAGUAAAACAGAUGCCUCCAUUUAGUUCUAGAAGGACCUUCUCCUUUAGUGUAACCAAGUGUUCAAAUUCCCUUCUUCUCUAUGAACUCAGCAUUCAUUUUAUCCAUAAUGAUCAAUUUAAAAGUAGAGAAACUUGUCAGUUGAGAGAUCUGAUUCCCAAGAGAUUGGUUUCACUUGUCUACCUGAAUUUUGUGAUUGGAUUUUGUUGUUCGUUUUUUAAGAUUGAAUUUUGUUACCACCCCCA-3'- Poly-A tail
  • Coding region
NCBI Matured mRNA sequence viewer
;
More about the NCBI sViewer.
DNA
DNA (Gene ID: 117248)
GALNT15
polypeptide N-acetylgalactosaminyltransferase 15
NC_000003.12
3  16175152.. 16227500
16175152.. 16227500
strand +
CCDS33711.1
MGI:1926004
ClinVar, dbVar
ENSG00000131386
GALNT7, pp-GalNAc-T15
uc003car.5
INSDC: AY358443
21531
615131
OTTHUMG00000156893
ENA, DDBJ, Monarch
NCBI CDS Gene viewer
More about the NCBI sViewer.
NCBI CDS gene sequence (1920 bp)
5'-ATGCTCCTAAGGAAGCGATACAGGCACAGACCATGCAGACTCCAGTTCCTCCTGCTGCTCCTGATGCTGGGATGCGTCCTGATGATGGTGGCGATGTTGCACCCTCCCCACCACACCCTGCACCAGACTGTCACAGCCCAAGCCAGCAAGCACAGCCCTGAAGCCAGGTACCGCCTGGACTTTGGGGAATCCCAGGATTGGGTACTGGAAGCTGAGGATGAGGGTGAAGAGTACAGCCCTCTGGAGGGCCTGCCACCCTTTATCTCACTGCGGGAGGATCAGCTGCTGGTGGCCGTGGCCTTACCCCAGGCCAGAAGGAACCAGAGCCAGGGCAGGAGAGGTGGGAGCTACCGCCTCATCAAGCAGCCAAGGAGGCAGGATAAGGAAGCCCCAAAGAGGGACTGGGGGGCTGATGAGGACGGGGAGGTGTCTGAAGAAGAGGAGTTGACCCCGTTCAGCCTGGACCCACGTGGCCTCCAGGAGGCACTCAGTGCCCGCATCCCCCTCCAGAGGGCTCTGCCCGAGGTGCGGCACCCACTGTGTCTGCAGCAGCACCCTCAGGACAGCCTGCCCACAGCCAGCGTCATCCTCTGTTTCCATGATGAGGCCTGGTCCACTCTCCTGCGGACTGTACACAGCATCCTCGACACAGTGCCCAGGGCCTTCCTGAAGGAGATCATCCTCGTGGACGACCTCAGCCAGCAAGGACAACTCAAGTCTGCTCTCAGCGAATATGTGGCCAGGCTGGAGGGGGTGAAGTTACTCAGGAGCAACAAGAGGCTGGGTGCCATCAGGGCCCGGATGCTGGGGGCCACCAGAGCCACCGGGGATGTGCTCGTCTTCATGGATGCCCACTGCGAGTGCCACCCAGGCTGGCTGGAGCCCCTCCTCAGCAGAATAGCTGGTGACAGGAGCCGAGTGGTATCTCCGGTGATAGATGTGATTGACTGGAAGACTTTCCAGTATTACCCCTCAAAGGACCTGCAGCGTGGGGTGTTGGACTGGAAGCTGGATTTCCACTGGGAACCTTTGCCAGAGCATGTGAGGAAGGCCCTCCAGTCCCCCATAAGCCCCATCAGGAGCCCTGTGGTGCCCGGAGAGGTGGTGGCCATGGACAGACATTACTTCCAAAACACTGGAGCGTATGACTCTCTTATGTCGCTGCGAGGTGGTGAAAACCTCGAACTGTCTTTCAAGGCCTGGCTCTGTGGTGGCTCTGTTGAAATCCTTCCCTGCTCTCGGGTAGGACACATCTACCAAAATCAGGATTCCCATTCCCCCCTCGACCAGGAGGCCACCCTGAGGAACAGGGTTCGCATTGCTGAGACCTGGCTGGGGTCATTCAAAGAAACCTTCTACAAGCATAGCCCAGAGGCCTTCTCCTTGAGCAAGGCTGAGAAGCCAGACTGCATGGAACGCTTGCAGCTGCAAAGGAGACTGGGTTGTCGGACATTCCACTGGTTTCTGGCTAATGTCTACCCTGAGCTGTACCCATCTGAACCCAGGCCCAGTTTCTCTGGAAAGCTCCACAACACTGGACTTGGGCTCTGTGCAGACTGCCAGGCAGAAGGGGACATCCTGGGCTGTCCCATGGTGTTGGCTCCTTGCAGTGACAGCCGGCAGCAACAGTACCTGCAGCACACCAGCAGGAAGGAGATTCACTTTGGCAGCCCACAGCACCTGTGCTTTGCTGTCAGGCAGGAGCAGGTGATTCTTCAGAACTGCACGGAGGAAGGCCTGGCCATCCACCAGCAGCACTGGGACTTCCAGGAGAATGGGATGATTGTCCACATTCTTTCTGGGAAATGCATGGAAGCTGTGGTGCAAGAAAACAATAAAGATTTGTACCTGCGTCCGTGTGATGGAAAAGCCCGCCAGCAGTGGCGTTTTGACCAGATCAATGCTGTGGATGAACGATGA-3'
NCBI CDS gene sequence with introns (location: 16175152.. 16227500) (52349 bp)Download
NCBI Gene Viewer (CDS + introns)
NCBI CDS gene sequence with introns, 5'UTR and 3'UTR (location: 16174680.. 16230165) (55486 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions)
NCBI gene sequence (location: [16174680 - 1000].. 16230165) (56486 bp)Download
NCBI Gene Viewer (CDS + introns + Untranslated regions + 1000 dNTP to potentially reach the promotor)
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