SMTL ID : 8h4v.1 (1 other biounit)

Mincle CRD complex with PGL trisaccharide

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.40 Å

Oligo State

monomer

Ligands

1 x MRP- 7CV- L6N: (2~{R},3~{R},4~{S},5~{S},6~{R})-6-(methoxymethyl)oxane-2,3,4,5-tetrol-(1-4)-6-deoxy-2,3-di-O-methyl-alpha-L-mannopyranose-(1-2)-3-O-methyl-alpha-L-rhamnopyranose

MRP-7CV-L6N.1: 7 residues within 4Å: Chain A: E.108, N.110, E.116, R.122, N.132, D.133 Ligands: CA.2 7 PLIP interactions: 7 interactions with chain A Hydrogen bonds: A:E.108, A:E.108, A:N.110, A:E.116, A:R.122, A:R.122, A:N.132

3 x CA: CALCIUM ION(Non-covalent)

CA.2: 7 residues within 4Å: Chain A: E.108, P.109, N.110, E.116, N.132, D.133 Ligands: MRP-7CV-L6N.1 4 PLIP interactions: 4 interactions with chain A Metal complexes: A:E.108, A:E.116, A:D.133, A:D.133 CA.3: 5 residues within 4Å: Chain A: D.82, E.86, N.111, E.116, D.117 5 PLIP interactions: 5 interactions with chain A Metal complexes: A:D.82, A:E.86, A:E.86, A:E.116, A:D.117 CA.4: 4 residues within 4Å: Chain A: V.56, N.58, E.62, E.145 4 PLIP interactions: 4 interactions with chain A Metal complexes: A:V.56, A:E.62, A:E.145, A:E.145

Links

RCSB   PDBe   PDBe-KB   PDBj   PDBsum   CATH   PLIP

Citation

Ishizuka, S. et al., PGL-III, a Rare Intermediate of Mycobacterium leprae Phenolic Glycolipid Biosynthesis, Is a Potent Mincle Ligand. Acs Cent.Sci. (2023)

Release Date

2023-08-09

Peptides

C-type lectin domain family 4 member E: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

C-type lectin domain family 4 member E

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