7zqx.1 | SWISS-MODEL Template Library

SMTL ID : 7zqx.1

Human galectin-3c in complex with a galactose derivative

Coordinates
PDB Format
Method
X-RAY DIFFRACTION 1.05 Å
Oligo State
monomer
Ligands
1 x GOL: GLYCEROL(Non-functional Binders)
1 x SCN: THIOCYANATE ION(Non-functional Binders)
3 x CL: CHLORIDE ION(Non-functional Binders)
1 x JU0: (2~{R},3~{R},4~{S},5~{R},6~{R})-2-(5-bromanylpyridin-3-yl)sulfanyl-6-(hydroxymethyl)-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol(Non-covalent)
1 x MOH: METHANOL(Non-functional Binders)
Links
RCSB   PDBe   PDBe-KB   PDBj   PDBsum   CATH   PLIP
Citation
Zetterberg, F.R. et al., Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease. J.Med.Chem. (2022)
Release Date
2022-11-02
Peptides
Galectin-3: A
SMTL:PDB
SMTL Chain Id:
PDB Chain Id:
A
A

Galectin-3

Related Entries With Identical Sequence

2xg3.1 | 4bm8.1