7xfa.1 | SWISS-MODEL Template Library

SMTL ID : 7xfa.1

Structure of human Galectin-3 CRD in complex with monosaccharide inhibitor

Coordinates
PDB Format
Method
X-RAY DIFFRACTION 0.98 Å
Oligo State
monomer
Ligands
1 x D9J: (2~{S},3~{R},4~{R},5~{R},6~{R})-4-[4-[4-chloranyl-3,5-bis(fluoranyl)phenyl]-1,2,3-triazol-1-yl]-2-[2-[5-chloranyl-2-(trifluoromethyl)phenyl]-5-methyl-1,2,4-triazol-3-yl]-6-(hydroxymethyl)oxane-3,5-diol(Non-covalent)
Links
RCSB   PDBe   PDBe-KB   PDBj   PDBsum   CATH   PLIP
Citation
Liu, C. et al., Identification of Monosaccharide Derivatives as Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin-3. J.Med.Chem. (2022)
Release Date
2022-10-12
Peptides
Galectin-3: A
SMTL:PDB
SMTL Chain Id:
PDB Chain Id:
A
A

Galectin-3

Related Entries With Identical Sequence

7cxa.1 | 7cxa.2 | 7df5.1