SMTL ID : 6z32.1 (1 other biounit)

Human cation-independent mannose 6-phosphate/IGF2 receptor domains 7-11

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 3.47 Å

Oligo State

monomer

Ligands

1 x NAG- NAG- BMA- MAN- MAN- MAN: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose

NAG-NAG-BMA-MAN-MAN-MAN.1: 10 residues within 4Å: Chain A: K.398, N.400, T.402, V.410, Y.411, Q.412, S.414, A.416, D.436, S.438 2 PLIP interactions: 2 interactions with chain A Hydrophobic interactions: A:Q.412 Hydrogen bonds: A:Q.412

1 x SO4: SULFATE ION

SO4.2: 5 residues within 4Å: Chain A: S.473, R.474, Y.475, S.476, D.477 4 PLIP interactions: 4 interactions with chain A Hydrogen bonds: A:Y.475, A:S.476, A:S.476 Salt bridges: A:R.474

1 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose

NAG.3: 2 residues within 4Å: Chain A: N.39, C.58 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:N.39

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Bochel, A.J. et al., Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9. Structure (2020)

Release Date

2020-08-19

Peptides

Cation-independent mannose-6-phosphate receptor: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

Cation-independent mannose-6-phosphate receptor

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