SMTL ID : 6q77.1

Structure of Fucosylated D-antimicrobial peptide SB12 in complex with the Fucose-binding lectin PA-IIL at 2.002 Angstrom resolution

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.00 Å

Oligo State

monomer

Ligands

1 x DLE- DLY- DAL- DLE- DLY- DLY- DLE- DAL: SB12(Non-covalent)

DLE-DLY-DAL-DLE-DLY-DLY-DLE-DAL.1: 3 residues within 4Å: Chain A: S.23, G.24 Ligands: ZDC.4 No protein-ligand interaction detected (PLIP)

2 x CA: CALCIUM ION(Non-covalent)

CA.2: 6 residues within 4Å: Chain A: E.95, D.99, D.101, D.104 Ligands: CA.3, ZDC.4 5 PLIP interactions: 5 interactions with chain A Metal complexes: A:E.95, A:E.95, A:D.99, A:D.101, A:D.104 CA.3: 6 residues within 4Å: Chain A: N.21, D.101, N.103, D.104 Ligands: CA.2, ZDC.4 3 PLIP interactions: 3 interactions with chain A Metal complexes: A:N.21, A:D.101, A:D.104

1 x ZDC: 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid(Non-covalent)

ZDC.4: 12 residues within 4Å: Chain A: N.21, S.22, S.23, E.95, D.96, D.99, D.101, D.104 Ligands: DLE-DLY-DAL-DLE-DLY-DLY-DLE-DAL.1, DLE-DLY-DAL-DLE-DLY-DLY-DLE-DAL.1, CA.2, CA.3 4 PLIP interactions: 4 interactions with chain A Hydrogen bonds: A:S.23, A:D.99, A:D.104, A:D.104

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Baeriswyl, S. et al., X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. Acs Chem.Biol. (2019)

Release Date

2019-03-20

Peptides

Fucose-binding lectin: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

Fucose-binding lectin

Related Entries With Identical Sequence