SMTL ID : 6gw4.1

GII.19 human norovirus protruding domain in complex with glycochenodeoxycholate (GCDCA)

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.30 Å

Oligo State

monomer

Ligands

1 x CHO: GLYCOCHENODEOXYCHOLIC ACID(Non-covalent)

CHO.1: 11 residues within 4Å: Chain A: H.76, Q.77, K.108, P.136, T.138, S.139, A.140, G.152, T.153, W.154, L.172 7 PLIP interactions: 7 interactions with chain A Hydrophobic interactions: A:H.76, A:K.108, A:P.136, A:W.154, A:L.172 Hydrogen bonds: A:T.138, A:A.140

4 x EDO: 1,2-ETHANEDIOL(Non-functional Binders)

EDO.2: 2 residues within 4Å: Chain A: Q.236, Q.240 3 PLIP interactions: 3 interactions with chain A Water bridges: A:Q.236, A:Q.236, A:Q.240 EDO.3: 2 residues within 4Å: Chain A: V.7, Y.291 No protein-ligand interaction detected (PLIP) EDO.4: 2 residues within 4Å: Chain A: F.294, D.295 No protein-ligand interaction detected (PLIP) EDO.5: 1 residues within 4Å: Chain A: V.7 No protein-ligand interaction detected (PLIP)

Links

RCSB   PDBe   PDBe-KB   PDBj   PDBsum   CATH   PLIP

Citation

Kilic, T. et al., Structural Basis for Human Norovirus Capsid Binding to Bile Acids. J. Virol. (2019)

Release Date

2018-10-17

Peptides

Capsid protein: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

Capsid protein