SMTL ID : 6gw1.1

GII.10 human norovirus protruding domain in complex with glycochenodeoxycholate (GCDCA)

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.90 Å

Oligo State

homo-dimer

Ligands

2 x NA: SODIUM ION(Non-functional Binders)

NA.1: 7 residues within 4Å: Chain A: Q.38, N.39, T.51, T.103, P.104, D.105, Y.192 3 PLIP interactions: 3 interactions with chain A Hydrogen bonds: A:N.39, A:T.103, A:Y.192 NA.3: 6 residues within 4Å: Chain B: Q.38, T.51, T.103, P.104, D.105, Y.192 3 PLIP interactions: 3 interactions with chain B Hydrogen bonds: B:N.39, B:T.51, B:T.103

2 x CHO: GLYCOCHENODEOXYCHOLIC ACID(Non-covalent)

CHO.2: 11 residues within 4Å: Chain A: H.74, R.75, G.76, Q.109, V.137, Y.141, S.142, P.143, S.155, T.156, W.157 5 PLIP interactions: 5 interactions with chain A Hydrophobic interactions: A:V.137, A:V.137, A:W.157, A:W.157 Hydrogen bonds: A:R.75 CHO.4: 11 residues within 4Å: Chain B: H.74, R.75, G.76, H.78, Q.109, V.137, Y.141, S.142, S.155, T.156, W.157 5 PLIP interactions: 5 interactions with chain B Hydrophobic interactions: B:V.137, B:V.137, B:W.157 Water bridges: B:Q.109, B:Y.141

Links

RCSB   PDBe   PDBe-KB   PDBj   PDBsum   CATH   PLIP

Citation

Kilic, T. et al., Structural Basis for Human Norovirus Capsid Binding to Bile Acids. J. Virol. (2019)

Release Date

2018-10-17

Peptides

Capsid protein: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
B

Capsid protein

Related Entries With Identical Sequence