SMTL ID : 6a1t.1

Charcot-Leyden crystal protein/Galectin-10 variant E33A with lactose

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.97 Å

Oligo State

homo-dimer

Ligands

2 x BGC- GAL: beta-D-galactopyranose-(1-4)-beta-D-glucopyranose(Non-covalent)

BGC-GAL.1: 7 residues within 4Å: Chain A: H.56, Q.58, V.66, N.68, W.75, Q.78 Chain B: R.63 7 PLIP interactions: 5 interactions with chain A, 2 interactions with chain B Hydrogen bonds: A:N.68, A:Q.78, A:Q.58, A:Q.58, A:N.68, B:R.63 Water bridges: A:K.76, A:W.75, A:R.131, B:N.35 BGC-GAL.2: 7 residues within 4Å: Chain A: R.63 Chain B: H.56, Q.58, V.66, N.68, W.75, Q.78 7 PLIP interactions: 5 interactions with chain B, 2 interactions with chain A Hydrogen bonds: B:N.68, B:Q.78, B:Q.58, B:Q.58, B:N.68, A:R.63 Water bridges: B:K.76, B:W.75, B:R.131, A:N.35

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Su, J. et al., Identification of key amino acid residues determining ligand binding specificity, homodimerization and cellular distribution of human galectin-10. Glycobiology (2019)

Release Date

2018-12-26

Peptides

Galectin-10: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
A

Galectin-10

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