SMTL ID : 5xau.1 (1 other biounit)

Crystal structure of integrin binding fragment of laminin-511

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.80 Å

Oligo State

hetero-1-1-1-mer

Ligands

1 x NAG- NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)

NAG-NAG.1: 4 residues within 4Å: Chain A: E.342, H.475, H.477, N.634 No protein-ligand interaction detected (PLIP)

1 x CA: CALCIUM ION(Non-covalent)

CA.2: 5 residues within 4Å: Chain A: D.140, L.157, L.213, N.215, D.566 5 PLIP interactions: 4 interactions with chain A, 1 Ligand-Water interactions Metal complexes: A:D.140, A:L.157, A:L.213, A:D.566, H2O.9

3 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)

NAG.3: 1 residues within 4Å: Chain A: N.54 No protein-ligand interaction detected (PLIP) NAG.4: 3 residues within 4Å: Chain A: N.556, T.558, W.561 3 PLIP interactions: 3 interactions with chain A Hydrogen bonds: A:N.556, A:T.558, A:T.558 NAG.5: 10 residues within 4Å: Chain A: H.477, G.478, L.596, P.597, E.598, S.599, G.600, I.602, N.604, V.633 2 PLIP interactions: 2 interactions with chain A Hydrogen bonds: A:E.598, A:E.598

Links

RCSB   PDBe   PDBe-KB   PDBj   PDBsum   CATH   PLIP

Citation

Takizawa, M. et al., Mechanistic basis for the recognition of laminin-511 by alpha 6 beta 1 integrin. Sci Adv (2017)

Release Date

2017-09-20

Peptides

Laminin subunit alpha-5: A
Laminin subunit beta-1: B
Laminin subunit gamma-1: C

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
B

C
C

Laminin subunit alpha-5

Laminin subunit beta-1

Laminin subunit gamma-1

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