SMTL ID : 5nfa.1

Structure of Galectin-3 CRD in complex with compound 3

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.59 Å

Oligo State

monomer

Ligands

1 x TVD- TVM: 3-O-[(3-methoxyphenyl)methyl]-beta-D-galactopyranose-(1-4)-N-acetyl-2-(acetylamino)-2-deoxy-beta-D-glucopyranosylamine(Non-covalent)

TVD-TVM.1: 8 residues within 4Å: Chain A: R.41, H.55, N.57, R.59, N.71, W.78, E.81, R.83 6 PLIP interactions: 6 interactions with chain A Hydrogen bonds: A:R.59, A:R.59, A:R.83, A:N.57, A:R.59, A:N.71 Water bridges: A:E.62, A:R.41, A:N.57 pi-Cation interactions: A:R.41

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Atmanene, C. et al., Biophysical and structural characterization of mono/di-arylated lactosamine derivatives interaction with human galectin-3. Biochem. Biophys. Res. Commun. (2017)

Release Date

2017-06-21

Peptides

Galectin-3: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

Galectin-3

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