SMTL ID : 5k8y.1

Structure of the Mus musclus Langerin carbohydrate recognition domain

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.40 Å

Oligo State

homo-dimer

Ligands

2 x CA: CALCIUM ION(Non-covalent)

CA.1: 5 residues within 4Å: Chain A: E.98, N.100, E.106, N.120, D.121 5 PLIP interactions: 4 interactions with chain A, 1 Ligand-Water interactions Metal complexes: A:E.98, A:E.106, A:D.121, A:D.121, H2O.1 CA.5: 5 residues within 4Å: Chain B: E.98, N.100, E.106, N.120, D.121 4 PLIP interactions: 4 interactions with chain B Metal complexes: B:E.98, B:E.106, B:D.121, B:D.121

3 x P6G: HEXAETHYLENE GLYCOL(Non-functional Binders)

P6G.2: 6 residues within 4Å: Chain A: T.28, D.125, T.127 Chain B: D.125, T.127 Ligands: P6G.3 No protein-ligand interaction detected (PLIP) P6G.3: 5 residues within 4Å: Chain A: P.123, D.125, N.126, T.127 Ligands: P6G.2 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:T.127 P6G.4: 7 residues within 4Å: Chain A: Y.30, E.33, H.42, Y.78, V.80 Chain B: Y.30, V.80 2 PLIP interactions: 1 interactions with chain B, 1 interactions with chain A Hydrogen bonds: B:Q.82, A:Y.78

1 x GOL: GLYCEROL(Non-functional Binders)

GOL.6: 6 residues within 4Å: Chain B: N.110, R.112, N.120, G.122, N.126, F.128 3 PLIP interactions: 3 interactions with chain B Hydrogen bonds: B:N.110, B:N.120, B:N.126

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Hanske, J. et al., Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent. J. Biol. Chem. (2017)

Release Date

2016-12-07

Peptides

C-type lectin domain family 4 member K: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
B

C-type lectin domain family 4 member K