SMTL ID : 5ik4.1

Laminin A2LG45 C-form, Apo.

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.27 Å

Oligo State

monomer

Ligands

2 x CA: CALCIUM ION(Non-covalent)

CA.1: 6 residues within 4Å: Chain A: D.83, L.100, G.101, I.149, L.150, D.151 6 PLIP interactions: 4 interactions with chain A, 2 Ligand-Water interactions Metal complexes: A:D.83, A:L.100, A:I.149, A:D.151, H2O.1, H2O.13 CA.2: 6 residues within 4Å: Chain A: D.257, N.274, G.275, S.328, A.329, D.330 5 PLIP interactions: 4 interactions with chain A, 1 Ligand-Water interactions Metal complexes: A:D.257, A:N.274, A:S.328, A:D.330, H2O.14

1 x A2G: 2-acetamido-2-deoxy-alpha-D-galactopyranose(Post Translational Modification)

A2G.3: 4 residues within 4Å: Chain A: T.16, M.17, V.18, A.24 No protein-ligand interaction detected (PLIP)

1 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)

NAG.4: 2 residues within 4Å: Chain A: I.163, N.164 2 PLIP interactions: 2 interactions with chain A Hydrophobic interactions: A:I.163 Hydrogen bonds: A:N.164

2 x GOL: GLYCEROL(Non-functional Binders)

GOL.5: 2 residues within 4Å: Chain A: T.166, R.168 2 PLIP interactions: 2 interactions with chain A Hydrogen bonds: A:R.168, A:R.168 GOL.6: 7 residues within 4Å: Chain A: R.90, S.97, S.106, R.169, I.170, G.171, P.172 2 PLIP interactions: 2 interactions with chain A Hydrogen bonds: A:R.90, A:R.90

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Briggs, D.C. et al., Structural basis of laminin binding to the LARGE glycans on dystroglycan. Nat.Chem.Biol. (2016)

Release Date

2016-08-10

Peptides

Laminin subunit alpha-2: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

Laminin subunit alpha-2

Related Entries With Identical Sequence