SMTL ID : 5ihb.1 (1 other biounit)

Structure of the immune receptor CD33

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.24 Å

Oligo State

homo-dimer

Ligands

6 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)

NAG.1: 5 residues within 4Å: Chain A: L.21, L.76, G.77, N.83, S.85 2 PLIP interactions: 2 interactions with chain A Hydrogen bonds: A:N.83 Water bridges: A:D.78 NAG.2: 3 residues within 4Å: Chain A: N.143, P.172, I.181 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:N.143 NAG.3: 4 residues within 4Å: Chain A: T.191, N.192, T.209, Q.211 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:N.192 NAG.4: 6 residues within 4Å: Chain B: L.21, T.25, L.76, G.77, N.83, S.85 2 PLIP interactions: 2 interactions with chain B Hydrogen bonds: B:L.76, B:N.83 NAG.5: 4 residues within 4Å: Chain B: N.143, G.171, P.172, I.181 1 PLIP interactions: 1 interactions with chain B Hydrogen bonds: B:N.143 NAG.6: 5 residues within 4Å: Chain A: P.167, T.168 Chain B: N.192, T.209, Q.211 4 PLIP interactions: 4 interactions with chain B Hydrogen bonds: B:N.192, B:T.209, B:T.209, B:Q.211

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Dodd, R.B. et al., Structure of ligand bound CD33 receptor associated with Alzheimer's disease. To Be Published

Release Date

2017-03-29

Peptides

Myeloid cell surface antigen CD33: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
D

Myeloid cell surface antigen CD33

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