SMTL ID : 4r9a.1

Crystal structure of Human galectin-3 CRD in complex with lactose (pH 7.0, PEG4000)

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.20 Å

Oligo State

monomer

Ligands

1 x BGC- GAL: beta-D-galactopyranose-(1-4)-beta-D-glucopyranose(Non-covalent)

BGC-GAL.1: 7 residues within 4Å: Chain A: H.52, N.54, R.56, N.68, W.75, E.78, R.80 6 PLIP interactions: 6 interactions with chain A Hydrogen bonds: A:R.56, A:R.56, A:E.78, A:R.80, A:R.56, A:N.68, A:E.78 Water bridges: A:E.59, A:E.59, A:R.38, A:R.38, A:N.54

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Su, J. et al., The water network in galectin-3 ligand binding site guides inhibitor design. ACTA BIOCHIM.BIOPHYS.SIN. (2015)

Release Date

2015-03-11

Peptides

Galectin-3: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

Galectin-3

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