SMTL ID : 4p2n.1 (1 other biounit)

Structure of the P domain from a GI.7 Norovirus variant in complex with LeX HBGA

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.70 Å

Oligo State

homo-dimer

Ligands

2 x NAG- FUC- GAL: alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose(Non-covalent)(Non-functional Binders)

NAG-FUC-GAL.1: 9 residues within 4Å: Chain A: D.107, H.109, S.162, P.163, T.165, S.166, V.211 Chain B: S.120, G.121 7 PLIP interactions: 2 interactions with chain B, 5 interactions with chain A Hydrogen bonds: B:G.121, A:D.107, A:H.109, A:S.162, A:S.162 Water bridges: B:L.119, A:S.166 NAG-FUC-GAL.2: 8 residues within 4Å: Chain A: S.120, G.121 Chain B: D.107, H.109, S.162, P.163, S.166, V.211 6 PLIP interactions: 2 interactions with chain A, 4 interactions with chain B Hydrogen bonds: A:G.121, B:D.107, B:H.109, B:S.162, B:S.162 Water bridges: A:S.120

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Shanker, S. et al., Structural analysis of determinants of histo-blood group antigen binding specificity in genogroup I noroviruses. J.Virol. (2014)

Release Date

2014-04-02

Peptides

Major capsid protein: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
B

Major capsid protein

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