SMTL ID : 4gwj.1

His 62 mutant of the lectin binding domain of Lectinolysin complexed with Lewis b

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.60 Å

Oligo State

monomer

Ligands

1 x NAG- GAL- FUC- FUC: alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose(Non-covalent)

NAG-GAL-FUC-FUC.1: 9 residues within 4Å: Chain A: H.25, Y.41, G.42, H.48, F.51, R.75, D.77, G.78, R.83 1 PLIP interactions: 1 interactions with chain A Water bridges: A:G.42 Salt bridges: A:H.25

3 x MG: MAGNESIUM ION(Non-covalent)

MG.2: 1 residues within 4Å: Chain A: H.44 6 PLIP interactions: 1 interactions with chain A, 5 Ligand-Water interactions Metal complexes: A:H.44, H2O.4, H2O.6, H2O.6, H2O.6, H2O.6 MG.3: 1 residues within 4Å: Chain A: H.43 6 PLIP interactions: 1 interactions with chain A, 5 Ligand-Water interactions Metal complexes: A:H.43, H2O.2, H2O.2, H2O.2, H2O.3, H2O.6 MG.4: 2 residues within 4Å: Chain A: Q.17, D.60 5 PLIP interactions: 1 interactions with chain A, 4 Ligand-Water interactions Metal complexes: A:D.60, H2O.3, H2O.3, H2O.4, H2O.5

1 x CA: CALCIUM ION

CA.5: 6 residues within 4Å: Chain A: R.31, D.34, N.36, S.45, A.139, E.140 5 PLIP interactions: 5 interactions with chain A Metal complexes: A:R.31, A:D.34, A:N.36, A:A.139, A:E.140

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Lawrence, S.L. et al., Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin. Front Immunol (2012)

Release Date

2012-11-21

Peptides

Platelet aggregation factor Sm-hPAF: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

Platelet aggregation factor Sm-hPAF

Related Entries With Identical Sequence