SMTL ID : 4d3w.1

Crystal Structure of Epithelial Adhesin 1 A domain (Epa1A) from Candida glabrata in complex with the T-antigen (Galb1-3GalNAc)

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.50 Å

Oligo State

monomer

Ligands

1 x NGA- GAL: beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose(Non-covalent)

NGA-GAL.1: 9 residues within 4Å: Chain A: G.109, D.155, D.156, W.189, R.217, E.218, Y.219, D.220 Ligands: CA.2 5 PLIP interactions: 5 interactions with chain A Hydrogen bonds: A:D.155, A:R.217, A:R.217, A:E.218, A:D.220, A:E.218 Hydrophobic interactions: A:W.189 Water bridges: A:G.109, A:G.109, A:Y.219

1 x CA: CALCIUM ION(Non-covalent)

CA.2: 6 residues within 4Å: Chain A: D.155, D.156, N.216, E.218, D.220 Ligands: NGA-GAL.1 4 PLIP interactions: 4 interactions with chain A Metal complexes: A:D.155, A:D.156, A:E.218, A:D.220

1 x GOL: GLYCEROL(Non-covalent)

GOL.3: 5 residues within 4Å: Chain A: R.173, D.174, L.246, D.247, D.248 4 PLIP interactions: 4 interactions with chain A Hydrogen bonds: A:R.173, A:R.173, A:D.248 Water bridges: A:L.246

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Diderrich, R. et al., Structural Hotspots Determine Functional Diversity of the Candida Glabrata Epithelial Adhesin Family. J.Biol.Chem. (2015)

Release Date

2015-07-01

Peptides

EPITHELIAL ADHESIN 1: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

EPITHELIAL ADHESIN 1

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