SMTL ID : 4cz0.1

Structure of the A_mallard_Sweden_51_2002 H10 Avian Haemmaglutinin in complex with avian receptor analog Su-3SLN

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 3.20 Å

Oligo State

hetero-3-3-mer

Ligands

3 x NGS- GAL- SIA: N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranose(Post Translational Modification)

NGS-GAL-SIA.1: 10 residues within 4Å: Chain A: Y.88, T.126, T.127, K.128, W.144, H.176, E.183, L.187, Q.219, G.221 5 PLIP interactions: 5 interactions with chain A Hydrogen bonds: A:E.183, A:E.183, A:Q.219, A:Q.219, A:Y.88, A:T.126, A:K.128, A:H.176, A:Q.219 NGS-GAL-SIA.3: 10 residues within 4Å: Chain E: Y.88, T.126, T.127, K.128, N.136, W.144, H.176, E.183, L.187, Q.219 9 PLIP interactions: 9 interactions with chain E Hydrogen bonds: E:Q.219, E:Q.219, E:Y.88, E:T.126, E:T.127, E:K.128, E:N.136, E:E.183, E:Q.219, E:Q.219, E:Q.219 NGS-GAL-SIA.5: 10 residues within 4Å: Chain C: Y.88, G.125, T.126, T.127, K.128, W.144, H.176, E.183, L.187, Q.219 4 PLIP interactions: 4 interactions with chain C Hydrogen bonds: C:Q.219, C:Q.219, C:T.126, C:K.128, C:E.183, C:Q.219

3 x NAG- NAG- BMA- MAN- MAN: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)

NAG-NAG-BMA-MAN-MAN.2: 6 residues within 4Å: Chain A: R.293 Chain B: H.75, G.78, N.79, N.82 Chain C: E.104 No protein-ligand interaction detected (PLIP) NAG-NAG-BMA-MAN-MAN.4: 5 residues within 4Å: Chain C: R.293 Chain D: H.75, N.79, N.82 Chain E: E.104 No protein-ligand interaction detected (PLIP) NAG-NAG-BMA-MAN-MAN.6: 6 residues within 4Å: Chain A: E.104, I.254 Chain E: R.293 Chain F: H.75, N.79, N.82 No protein-ligand interaction detected (PLIP)

7 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)

NAG.7: 5 residues within 4Å: Chain A: R.162, G.233, D.234, N.235 Chain E: P.214 3 PLIP interactions: 2 interactions with chain A, 1 interactions with chain E Hydrogen bonds: A:R.162, A:G.233, E:Q.215 NAG.8: 2 residues within 4Å: Chain A: N.28, A.29 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:A.29 NAG.9: 3 residues within 4Å: Chain A: Q.215 Chain C: G.233, N.235 1 PLIP interactions: 1 interactions with chain C Hydrogen bonds: C:G.233 NAG.10: 4 residues within 4Å: Chain C: N.28, A.29, T.30, T.311 1 PLIP interactions: 1 interactions with chain C Hydrophobic interactions: C:T.311 NAG.11: 4 residues within 4Å: Chain E: R.162, G.233, D.234, N.235 3 PLIP interactions: 3 interactions with chain E Hydrogen bonds: E:R.162, E:G.233, E:N.235 NAG.12: 2 residues within 4Å: Chain E: N.28, A.29 No protein-ligand interaction detected (PLIP) NAG.13: 1 residues within 4Å: Chain F: N.154 No protein-ligand interaction detected (PLIP)

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Vachieri, S.G. et al., Receptor Binding by H10 Influenza Viruses. Nature (2014)

Release Date

2014-06-11

Peptides

HAEMAGGLUTININ: ACE
HAEMAGGLUTININ: BDF

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

C
C

E
E

B
B

D
D

F
F

HAEMAGGLUTININ

HAEMAGGLUTININ

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