SMTL ID : 4cr0.1

Crystal Structure of H5 (VN1194) Asn186Lys/Gly143Arg Mutant Haemagglutinin

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.65 Å

Oligo State

hetero-3-3-mer

Ligands

12 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)

NAG.1: 2 residues within 4Å: Chain A: Q.15, N.23 2 PLIP interactions: 2 interactions with chain A Hydrogen bonds: A:Q.15, A:N.23 NAG.2: 1 residues within 4Å: Chain A: N.154 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:N.154 NAG.3: 5 residues within 4Å: Chain A: N.165, N.236, D.237, A.238 Chain C: S.217 2 PLIP interactions: 2 interactions with chain A Hydrophobic interactions: A:A.238 Hydrogen bonds: A:N.236 NAG.4: 3 residues within 4Å: Chain B: E.147, E.150, N.154 2 PLIP interactions: 2 interactions with chain B Hydrogen bonds: B:E.147, B:E.150 NAG.5: 2 residues within 4Å: Chain C: Q.15, N.23 2 PLIP interactions: 2 interactions with chain C Hydrogen bonds: C:Q.15, C:N.23 NAG.6: 1 residues within 4Å: Chain C: N.154 1 PLIP interactions: 1 interactions with chain C Hydrogen bonds: C:N.154 NAG.7: 5 residues within 4Å: Chain C: N.165, N.236, D.237, A.238 Chain E: S.217 2 PLIP interactions: 2 interactions with chain C Hydrophobic interactions: C:A.238 Hydrogen bonds: C:N.236 NAG.8: 3 residues within 4Å: Chain D: E.147, E.150, N.154 2 PLIP interactions: 2 interactions with chain D Hydrogen bonds: D:E.147, D:E.150 NAG.9: 2 residues within 4Å: Chain E: Q.15, N.23 2 PLIP interactions: 2 interactions with chain E Hydrogen bonds: E:Q.15, E:N.23 NAG.10: 1 residues within 4Å: Chain E: N.154 1 PLIP interactions: 1 interactions with chain E Hydrogen bonds: E:N.154 NAG.11: 5 residues within 4Å: Chain A: S.217 Chain E: N.165, N.236, D.237, A.238 2 PLIP interactions: 2 interactions with chain E Hydrophobic interactions: E:A.238 Hydrogen bonds: E:N.236 NAG.12: 3 residues within 4Å: Chain F: E.147, E.150, N.154 2 PLIP interactions: 2 interactions with chain F Hydrogen bonds: F:E.147, F:E.150

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Xiong, X. et al., Enhanced Human Receptor Binding by H5 Haemagglutinins. Virology (2014)

Release Date

2014-05-28

Peptides

Hemagglutinin HA1: ACE
Hemagglutinin HA2: BDF

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

C
A

E
A

B
B

D
B

F
B

Hemagglutinin HA1

Hemagglutinin HA2