SMTL ID : 4coy.1

Crystal Structure of Epithelial Adhesin 6 A domain (Epa6A) from Candida glabrata in complex with Galb1-4GlcNAc

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.80 Å

Oligo State

monomer

Ligands

1 x NAG- GAL: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose(Non-covalent)

NAG-GAL.1: 10 residues within 4Å: Chain A: G.101, C.102, D.147, D.148, W.181, R.209, D.210, N.211, D.212 Ligands: CA.2 3 PLIP interactions: 3 interactions with chain A Hydrogen bonds: A:D.147, A:R.209, A:R.209, A:D.210, A:D.210, A:N.211, A:D.212, A:C.102, A:N.211 Water bridges: A:D.212, A:R.209

1 x CA: CALCIUM ION(Non-covalent)

CA.2: 6 residues within 4Å: Chain A: D.147, D.148, N.208, D.210, D.212 Ligands: NAG-GAL.1 4 PLIP interactions: 4 interactions with chain A Metal complexes: A:D.147, A:D.148, A:D.210, A:D.212

1 x ACT: ACETATE ION(Non-covalent)

ACT.3: 5 residues within 4Å: Chain A: S.50, Y.51, D.52, H.79, R.80 7 PLIP interactions: 7 interactions with chain A Hydrophobic interactions: A:D.52 Hydrogen bonds: A:S.50, A:S.50, A:D.52 Water bridges: A:R.80 Salt bridges: A:H.79, A:R.80

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Diderrich, R. et al., Structural Hotspots Determine Functional Diversity of the Candida Glabrata Epithelial Adhesin Family. J.Biol.Chem. (2015)

Release Date

2015-02-18

Peptides

EPITHELIAL ADHESIN 6: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

EPITHELIAL ADHESIN 6