SMTL ID : 4cov.1

Crystal Structure of Epithelial Adhesin 6 A domain (Epa6A) from Candida glabrata in complex with Gala1-3Gal

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.50 Å

Oligo State

monomer

Ligands

1 x GAL- GLA: alpha-D-galactopyranose-(1-3)-beta-D-galactopyranose(Non-covalent)

GAL-GLA.1: 9 residues within 4Å: Chain A: C.115, D.160, D.161, W.194, R.222, D.223, N.224, D.225 Ligands: CA.2 8 PLIP interactions: 8 interactions with chain A Hydrogen bonds: A:N.224, A:D.160, A:R.222, A:R.222, A:D.223, A:D.223, A:N.224, A:D.225 Water bridges: A:G.114, A:D.225

1 x CA: CALCIUM ION(Non-covalent)

CA.2: 6 residues within 4Å: Chain A: D.160, D.161, N.221, D.223, D.225 Ligands: GAL-GLA.1 4 PLIP interactions: 4 interactions with chain A Metal complexes: A:D.160, A:D.161, A:D.223, A:D.225

1 x ACT: ACETATE ION(Non-covalent)

ACT.3: 5 residues within 4Å: Chain A: S.63, Y.64, D.65, H.92, R.93 6 PLIP interactions: 6 interactions with chain A Hydrophobic interactions: A:D.65 Hydrogen bonds: A:S.63, A:D.65 Water bridges: A:R.93 Salt bridges: A:H.92, A:R.93

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Diderrich, R. et al., Structural Hotspots Determine Functional Diversity of the Candida Glabrata Epithelial Adhesin Family. J.Biol.Chem. (2015)

Release Date

2015-02-18

Peptides

EPITHELIAL ADHESIN 6: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

EPITHELIAL ADHESIN 6

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