SMTL ID : 4b9h.1

Cladosporium fulvum LysM effector Ecp6 in complex with a beta-1,4- linked N-acetyl-D-glucosamine tetramer: I3C heavy atom derivative

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.10 Å

Oligo State

homo-dimer

Ligands

2 x NAG- NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)

NAG-NAG.1: 5 residues within 4Å: Chain A: E.107, N.133, H.190 Ligands: NAG.3, I3C.4 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:H.190 NAG-NAG.5: 5 residues within 4Å: Chain B: E.107, N.133, H.190 Ligands: NAG.7, I3C.8 1 PLIP interactions: 1 interactions with chain B Hydrogen bonds: B:H.190

2 x NDG- NAG- NAG- NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose(Post Translational Modification)

NDG-NAG-NAG-NAG.2: 26 residues within 4Å: Chain A: V.46, V.47, D.50, T.51, L.52, T.53, I.63, P.75, N.76, L.77, I.78, E.79, L.80, I.176, V.177, A.178, G.179, D.180, L.181, F.182, V.183, I.193, P.205, S.206, K.207, L.208 6 PLIP interactions: 6 interactions with chain A Hydrophobic interactions: A:I.176, A:I.63 Hydrogen bonds: A:E.79, A:L.80, A:G.179, A:D.180, A:L.208, A:T.53, A:N.76, A:N.76 Water bridges: A:V.210, A:L.52, A:L.52 NDG-NAG-NAG-NAG.6: 26 residues within 4Å: Chain B: V.46, V.47, D.50, T.51, L.52, T.53, I.63, P.75, N.76, L.77, I.78, E.79, L.80, I.176, V.177, A.178, G.179, D.180, L.181, F.182, V.183, I.193, P.205, S.206, K.207, L.208 7 PLIP interactions: 7 interactions with chain B Hydrophobic interactions: B:I.176, B:I.63 Hydrogen bonds: B:L.80, B:G.179, B:D.180, B:L.208, B:T.53, B:T.53, B:N.76, B:N.76 Water bridges: B:V.210, B:L.52, B:L.52

2 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose

NAG.3: 6 residues within 4Å: Chain A: E.107, C.109, C.163, P.164, N.222 Ligands: NAG-NAG.1 3 PLIP interactions: 3 interactions with chain A Hydrogen bonds: A:E.107, A:E.107, A:N.222 NAG.7: 6 residues within 4Å: Chain B: E.107, C.109, C.163, P.164, N.222 Ligands: NAG-NAG.5 3 PLIP interactions: 3 interactions with chain B Hydrogen bonds: B:E.107, B:E.107, B:N.222

2 x I3C: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid(Non-covalent)

I3C.4: 4 residues within 4Å: Chain A: H.190, D.219, K.221 Ligands: NAG-NAG.1 2 PLIP interactions: 2 interactions with chain A Hydrogen bonds: A:D.219 pi-Stacking: A:H.190 I3C.8: 4 residues within 4Å: Chain B: H.190, D.219, K.221 Ligands: NAG-NAG.5 2 PLIP interactions: 2 interactions with chain B Hydrogen bonds: B:D.219 pi-Stacking: B:H.190

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Sanchez-Vallet, A. et al., Fungal Effector Ecp6 Outcompetes Host Immune Receptor for Chitin Binding Through Intrachain Lysm Dimerization. Elife (2013)

Release Date

2013-07-17

Peptides

EXTRACELLULAR PROTEIN 6: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
A

EXTRACELLULAR PROTEIN 6

Related Entries With Identical Sequence