SMTL ID : 3zl1.1 (1 other biounit)

A thiazolyl-mannoside bound to FimH, monoclinic space group

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.55 Å

Oligo State

monomer

Ligands

1 x BWG: N-{5-[(1R)-1-hydroxyethyl]-1,3-thiazol-2-yl}-alpha-D-mannopyranosylamine(Non-covalent)

BWG.1: 11 residues within 4Å: Chain A: F.1, I.13, N.46, D.47, Y.48, I.52, D.54, Q.133, N.135, D.140, F.142 8 PLIP interactions: 8 interactions with chain A Hydrophobic interactions: A:Y.48 Hydrogen bonds: A:F.1, A:N.46, A:Y.48, A:Q.133, A:N.135, A:D.140 Water bridges: A:N.138

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Brument, S. et al., Thiazolylaminomannosides as Potent Antiadhesives of Type 1 Piliated Escherichia Coli Isolated from Crohn'S Disease Patients. J.Med.Chem. (2013)

Release Date

2013-07-10

Peptides

PROTEIN FIMH: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

PROTEIN FIMH

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