SMTL ID : 3t2t.1

Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.90 Å

Oligo State

homo-dimer

Ligands

1 x MQT: methyl 2-O-acetyl-3-O-(4-methylbenzoyl)-beta-D-talopyranoside(Non-covalent)

MQT.1: 10 residues within 4Å: Chain A: V.32, H.45, N.47, R.49, H.53, N.62, W.69, E.72, D.124, G.125 8 PLIP interactions: 8 interactions with chain A Hydrophobic interactions: A:V.32 Hydrogen bonds: A:R.49, A:N.62, A:E.72 Water bridges: A:H.45 Salt bridges: A:H.45, A:R.49, A:H.53

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Collins, P.M. et al., Taloside inhibitors of galectin-1 and galectin-3. Chem.Biol.Drug Des. (2012)

Release Date

2011-12-28

Peptides

Galectin-1: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
B

Galectin-1