SMTL ID : 3sej.1 (5 other biounits)

Structural characterization of a GII.4 2004 norovirus variant (TCH05) bound to Secretor Lewis HBGA (LeB)

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 3.04 Å

Oligo State

homo-dimer

Ligands

2 x BGC- GAL- NAG- GAL- FUC- FUC: alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose(Non-covalent)

BGC-GAL-NAG-GAL-FUC-FUC.1: 10 residues within 4Å: Chain A: S.123, T.124, R.125, D.154 Chain B: Q.170, D.171, G.172, S.173, S.222, G.223 1 PLIP interactions: 1 interactions with chain B Hydrogen bonds: B:G.172, B:S.173, B:S.173, B:S.222 BGC-GAL-NAG-GAL-FUC-FUC.2: 9 residues within 4Å: Chain A: D.171, G.172, S.173, S.222, G.223 Chain B: S.123, T.124, R.125, D.154 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:D.171, A:D.171, A:G.172, A:S.173, A:S.222

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Shanker, S. et al., Structural Analysis of Histo-Blood Group Antigen Binding Specificity in a Norovirus GII.4 Epidemic Variant: Implications for Epochal Evolution. J.Virol. (2011)

Release Date

2011-07-13

Peptides

Capsid: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
C

Capsid

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