SMTL ID : 3p7h.1 (3 other biounits)

Structure of the human Langerin carbohydrate recognition domain in complex with maltose

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.30 Å

Oligo State

monomer

Ligands

1 x GLC- GLC: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose(Non-covalent)

GLC-GLC.1: 7 residues within 4Å: Chain A: E.93, N.95, E.101, K.107, N.115, D.116 Ligands: CA.2 6 PLIP interactions: 6 interactions with chain A Hydrogen bonds: A:N.95, A:E.101, A:N.115, A:N.115 Water bridges: A:E.101, A:K.107

1 x CA: CALCIUM ION(Non-covalent)

CA.2: 6 residues within 4Å: Chain A: E.93, N.95, E.101, N.115, D.116 Ligands: GLC-GLC.1 4 PLIP interactions: 4 interactions with chain A Metal complexes: A:E.93, A:E.101, A:D.116, A:D.116

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Chatwell, L. et al., The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site. Mol.Immunol. (2008)

Release Date

2010-11-03

Peptides

C-type lectin domain family 4 member K: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

C-type lectin domain family 4 member K

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