SMTL ID : 3onu.1 (2 other biounits)

Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.39 Å

Oligo State

homo-dimer

Ligands

8 x EDO: 1,2-ETHANEDIOL(Non-functional Binders)

EDO.1: 9 residues within 4Å: Chain A: L.59, T.61, G.62, A.65, F.66, R.67, L.90, K.173 Chain B: P.25 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:T.61 EDO.2: 6 residues within 4Å: Chain A: Q.57, N.89, L.90, N.91, T.93, L.105 5 PLIP interactions: 5 interactions with chain A Hydrogen bonds: A:L.90, A:N.91, A:N.91 Water bridges: A:N.91, A:L.105 EDO.3: 9 residues within 4Å: Chain A: P.10, L.12, E.244, Q.247, H.248 Chain B: Q.247, H.248, Q.251 Ligands: EDO.7 3 PLIP interactions: 1 interactions with chain B, 2 interactions with chain A Water bridges: B:Q.247, A:H.248 Hydrogen bonds: A:H.248 EDO.4: 7 residues within 4Å: Chain A: R.79, G.80, T.81, V.141, S.159, T.160, W.161 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:S.159 EDO.5: 9 residues within 4Å: Chain A: P.25 Chain B: L.59, T.61, G.62, A.65, F.66, R.67, L.90, K.173 3 PLIP interactions: 3 interactions with chain B Hydrogen bonds: B:T.61, B:R.67, B:R.67 EDO.6: 6 residues within 4Å: Chain B: Q.57, N.89, L.90, N.91, T.93, L.105 5 PLIP interactions: 5 interactions with chain B Hydrogen bonds: B:L.90, B:N.91, B:N.91 Water bridges: B:N.91, B:L.105 EDO.7: 9 residues within 4Å: Chain A: Q.247, H.248, Q.251 Chain B: P.10, L.12, E.244, Q.247, H.248 Ligands: EDO.3 5 PLIP interactions: 3 interactions with chain A, 2 interactions with chain B Water bridges: A:Q.247, A:Q.247, A:Q.251, B:H.248 Hydrogen bonds: B:H.248 EDO.8: 8 residues within 4Å: Chain A: F.225, I.226, P.227, N.234 Chain B: R.67, S.119, R.121, K.173 2 PLIP interactions: 2 interactions with chain B Hydrogen bonds: B:R.67, B:R.121

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Hansman, G.S. et al., Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability. J.Virol. (2011)

Release Date

2011-05-11

Peptides

Capsid protein: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
B

Capsid protein

Related Entries With Identical Sequence