SMTL ID : 3m5i.1

Crystal structure of a H7 influenza virus hemagglutinin complexed with 6SLN

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 3.00 Å

Oligo State

hetero-3-3-mer

Ligands

3 x GAL- SIA: N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose(Non-covalent)(Post Translational Modification)

GAL-SIA.1: 11 residues within 4Å: Chain A: Y.92, G.128, A.129, T.130, S.131, W.146, L.148, H.178, E.185, L.189, R.215 5 PLIP interactions: 5 interactions with chain A Salt bridges: A:R.215 Hydrogen bonds: A:A.129, A:A.129, A:S.131, A:H.178, A:R.215 GAL-SIA.3: 12 residues within 4Å: Chain C: Y.92, A.129, T.130, S.131, W.146, L.148, H.178, S.180, E.181, E.185, L.189, R.215 7 PLIP interactions: 7 interactions with chain C Salt bridges: C:K.188 Hydrophobic interactions: C:L.189 Hydrogen bonds: C:A.129, C:T.130, C:S.131, C:S.180, C:E.181, C:R.215 GAL-SIA.6: 11 residues within 4Å: Chain E: Y.92, G.128, A.129, T.130, S.131, W.146, L.148, H.178, E.185, L.189, R.215 5 PLIP interactions: 5 interactions with chain E Hydrophobic interactions: E:L.189 Hydrogen bonds: E:A.129, E:S.131, E:H.178, E:R.215

4 x NAG- NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose(Non-covalent)(Post Translational Modification)

NAG-NAG.2: 7 residues within 4Å: Chain A: R.287 Chain B: E.69, E.72, Q.75, N.79, N.82 Chain E: R.108 1 PLIP interactions: 1 interactions with chain B Hydrophobic interactions: B:E.69 NAG-NAG.4: 3 residues within 4Å: Chain C: N.32, A.33, T.34 No protein-ligand interaction detected (PLIP) NAG-NAG.5: 6 residues within 4Å: Chain A: R.108 Chain C: R.287 Chain D: E.69, E.72, N.79, N.82 1 PLIP interactions: 1 interactions with chain D Hydrogen bonds: D:E.72 NAG-NAG.7: 7 residues within 4Å: Chain C: R.108 Chain E: R.287 Chain F: E.69, E.72, Q.75, N.79, N.82 1 PLIP interactions: 1 interactions with chain F Hydrophobic interactions: F:E.69

2 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)(Non-functional Binders)

NAG.8: 4 residues within 4Å: Chain A: N.32, A.33, T.34, T.305 2 PLIP interactions: 2 interactions with chain A Hydrogen bonds: A:T.34, A:T.34 NAG.9: 2 residues within 4Å: Chain E: N.32, A.33 No protein-ligand interaction detected (PLIP)

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Yang, H. et al., Structures of receptor complexes of a North American H7N2 influenza hemagglutinin with a loop deletion in the receptor binding site. Plos Pathog. (2010)

Release Date

2010-09-22

Peptides

Hemagglutinin: ACE
Hemagglutinin: BDF

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

C
C

E
E

B
B

D
D

F
F

Hemagglutinin

Hemagglutinin

Related Entries With Identical Sequence