SMTL ID : 3aye.1 (1 other biounit)

Crystal structure of galectin-3 CRD domian complexed with lactose

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.00 Å

Oligo State

monomer

Ligands

1 x BGC- GAL: beta-D-galactopyranose-(1-4)-beta-D-glucopyranose(Non-covalent)

BGC-GAL.1: 8 residues within 4Å: Chain A: H.43, N.45, R.47, V.57, N.59, W.66, E.69, R.71 5 PLIP interactions: 5 interactions with chain A Hydrogen bonds: A:R.47, A:R.47, A:E.69, A:R.71, A:R.47, A:N.59, A:E.69 Water bridges: A:W.66, A:E.69, A:N.45, A:W.66

2 x SO4: SULFATE ION(Non-functional Binders)

SO4.2: 1 residues within 4Å: Chain A: T.133 2 PLIP interactions: 2 interactions with chain A Hydrogen bonds: A:T.133, A:T.133 SO4.3: 5 residues within 4Å: Chain A: R.36, R.109, V.110, K.111, K.112 9 PLIP interactions: 9 interactions with chain A Hydrogen bonds: A:K.111, A:K.112 Water bridges: A:R.36, A:R.36, A:K.111, A:K.111 Salt bridges: A:R.36, A:K.111, A:K.112

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Bian, C.F. et al., Structural basis for distinct binding properties of the human galectins to thomsen-friedenreich antigen. Plos One (2011)

Release Date

2011-10-12

Peptides

Galectin-3: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

Galectin-3

Related Entries With Identical Sequence