SMTL ID : 2j0h.1 (1 other biounit)

L-ficolin complexed to acetyl-choline

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.85 Å

Oligo State

homo-trimer

Ligands

1 x NAG- NAG- BMA: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose(Non-covalent)

NAG-NAG-BMA.1: 1 residues within 4Å: Chain B: N.145 No protein-ligand interaction detected (PLIP)

3 x CA: CALCIUM ION(Non-covalent)(Post Translational Modification)(Non-functional Binders)

CA.2: 5 residues within 4Å: Chain A: D.154, D.156, N.158, T.159, G.160 5 PLIP interactions: 5 interactions with chain A Metal complexes: A:D.154, A:D.154, A:D.156, A:N.158, A:G.160 CA.5: 4 residues within 4Å: Chain B: D.154, D.156, N.158, G.160 5 PLIP interactions: 5 interactions with chain B Metal complexes: B:D.154, B:D.154, B:D.156, B:N.158, B:G.160 CA.7: 5 residues within 4Å: Chain C: D.154, D.156, N.158, T.159, G.160 5 PLIP interactions: 5 interactions with chain C Metal complexes: C:D.154, C:D.154, C:D.156, C:N.158, C:G.160

3 x ACH: ACETYLCHOLINE(Non-covalent)(Non-functional Binders)

ACH.3: 5 residues within 4Å: Chain A: D.41, D.43, G.44, G.45 Ligands: ACH.6 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:G.44 ACH.4: 4 residues within 4Å: Chain B: R.62, D.63, T.66, K.151 5 PLIP interactions: 5 interactions with chain B Hydrophobic interactions: B:D.63 Hydrogen bonds: B:D.63, B:T.66 Salt bridges: B:R.62, B:K.151 ACH.6: 5 residues within 4Å: Chain C: R.62, D.63, T.66, K.151 Ligands: ACH.3 4 PLIP interactions: 4 interactions with chain C Hydrogen bonds: C:D.63, C:T.66 Salt bridges: C:R.62, C:K.151

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Garlatti, V. et al., Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins. Embo J. (2007)

Release Date

2007-01-23

Peptides

FICOLIN-2: ABC

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
B

C
C

FICOLIN-2

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