SMTL ID : 2ds0.1 (1 other biounit)

Crystal structure of the earthworm lectin C-terminal domain mutant in complex with 6'-sialyllactose

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.80 Å

Oligo State

monomer

Ligands

1 x BGC- GAL- SIA: N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose

BGC-GAL-SIA.1: 10 residues within 4Å: Chain A: D.16, I.17, G.18, G.19, Q.20, I.29, W.31, K.34, N.41, S.109 2 PLIP interactions: 2 interactions with chain A Hydrogen bonds: A:D.16, A:G.19, A:Q.20, A:K.34, A:K.34, A:N.41, A:S.109, A:S.109

4 x SO4: SULFATE ION(Non-functional Binders)

SO4.2: 2 residues within 4Å: Chain A: K.116, H.118 1 PLIP interactions: 1 interactions with chain A Salt bridges: A:H.118 SO4.3: 4 residues within 4Å: Chain A: N.11, K.13, K.103, A.110 4 PLIP interactions: 4 interactions with chain A Hydrogen bonds: A:N.11, A:A.110 Water bridges: A:T.30 Salt bridges: A:K.103 SO4.4: 4 residues within 4Å: Chain A: S.104, D.105, K.106, H.111 5 PLIP interactions: 5 interactions with chain A Hydrogen bonds: A:D.105, A:K.106 Water bridges: A:H.111 Salt bridges: A:K.106, A:H.111 SO4.5: 1 residues within 4Å: Chain A: K.79 3 PLIP interactions: 3 interactions with chain A Water bridges: A:K.79, A:K.79 Salt bridges: A:K.79

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Yabe, R. et al., Tailoring a novel sialic acid-binding lectin from a ricin-B chain-like galactose-binding protein by natural evolution-mimicry. J.Biochem. (2007)

Release Date

2007-02-06

Peptides

29-kDa galactose-binding lectin: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

29-kDa galactose-binding lectin

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