SMTL ID : 2bpe.1

STRUCTURE OF MURINE DECTIN-1

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.25 Å

Oligo State

homo-dimer

Ligands

2 x CA: CALCIUM ION(Non-covalent)

CA.1: 4 residues within 4Å: Chain A: K.45, D.47, E.51, E.130 5 PLIP interactions: 4 interactions with chain A, 1 Ligand-Water interactions Metal complexes: A:K.45, A:E.51, A:E.51, A:E.130, H2O.2 CA.5: 4 residues within 4Å: Chain B: K.45, D.47, E.51, E.130 5 PLIP interactions: 4 interactions with chain B, 1 Ligand-Water interactions Metal complexes: B:K.45, B:E.51, B:E.130, B:E.130, H2O.6

4 x CL: CHLORIDE ION(Non-functional Binders)

CL.2: 4 residues within 4Å: Chain A: K.33, H.42, L.43, E.83 Ligand excluded by PLIP CL.3: 4 residues within 4Å: Chain A: D.47, N.48, N.91, S.92 Ligand excluded by PLIP CL.6: 3 residues within 4Å: Chain B: F.93, Q.94, R.96 Ligand excluded by PLIP CL.7: 4 residues within 4Å: Chain B: K.33, H.42, L.43, E.83 Ligand excluded by PLIP

2 x PG4: TETRAETHYLENE GLYCOL(Non-functional Binders)

PG4.4: 4 residues within 4Å: Chain A: Q.6, S.7, C.8, P.10 1 PLIP interactions: 1 interactions with chain A Water bridges: A:S.7 PG4.8: 4 residues within 4Å: Chain B: Q.6, S.7, C.8, P.10 No protein-ligand interaction detected (PLIP)

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Brown, J. et al., Structure of the Fungal Beta-Glucan-Binding Immune Receptor Dectin-1: Implications for Function. Protein Sci. (2007)

Release Date

2006-08-31

Peptides

DECTIN-1: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
B

DECTIN-1

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