SMTL ID : 1zro.1

Crystal structure of EBA-175 Region II (RII) crystallized in the presence of (alpha)2,3-sialyllactose

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.25 Å

Oligo State

homo-dimer

Ligands

16 x SO4: SULFATE ION(Non-functional Binders)

SO4.1: 5 residues within 4Å: Chain A: N.417, R.422 Chain B: K.28, N.29, R.31 Ligand excluded by PLIP SO4.2: 4 residues within 4Å: Chain A: T.54, Y.55, T.56, T.59 Ligand excluded by PLIP SO4.3: 3 residues within 4Å: Chain A: R.407, W.450, K.454 Ligand excluded by PLIP SO4.4: 6 residues within 4Å: Chain A: V.329, W.330, D.496, W.528, K.531, K.532 Ligand excluded by PLIP SO4.5: 2 residues within 4Å: Chain A: G.110, G.111 Ligand excluded by PLIP SO4.6: 4 residues within 4Å: Chain A: R.15, R.18, I.42, Q.43 Ligand excluded by PLIP SO4.7: 2 residues within 4Å: Chain A: N.438, K.439 Ligand excluded by PLIP SO4.8: 5 residues within 4Å: Chain A: W.458, K.468, C.471, K.472, E.473 Ligand excluded by PLIP SO4.11: 5 residues within 4Å: Chain A: K.28, N.29, R.31 Chain B: N.417, R.422 Ligand excluded by PLIP SO4.12: 5 residues within 4Å: Chain B: K.53, T.54, Y.55, T.56, T.59 Ligand excluded by PLIP SO4.13: 3 residues within 4Å: Chain B: R.407, W.450, K.454 Ligand excluded by PLIP SO4.14: 6 residues within 4Å: Chain B: V.329, W.330, D.496, W.528, K.531, K.532 Ligand excluded by PLIP SO4.15: 2 residues within 4Å: Chain B: G.110, G.111 Ligand excluded by PLIP SO4.16: 4 residues within 4Å: Chain B: R.15, R.18, I.42, Q.43 Ligand excluded by PLIP SO4.17: 2 residues within 4Å: Chain B: N.438, K.439 Ligand excluded by PLIP SO4.18: 5 residues within 4Å: Chain B: W.458, K.468, C.471, K.472, E.473 Ligand excluded by PLIP

4 x CL: CHLORIDE ION(Non-functional Binders)

CL.9: 1 residues within 4Å: Chain A: K.150 Ligand excluded by PLIP CL.10: 1 residues within 4Å: Chain A: R.437 Ligand excluded by PLIP CL.19: 1 residues within 4Å: Chain B: K.150 Ligand excluded by PLIP CL.20: 1 residues within 4Å: Chain B: R.437 Ligand excluded by PLIP

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Tolia, N.H. et al., Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum. Cell(Cambridge,Mass.) (2005)

Release Date

2005-08-09

Peptides

erythrocyte binding antigen region II: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
B

erythrocyte binding antigen region II

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