SMTL ID : 1yxw.1

A common binding site for disialyllactose and a tri-peptide in the C-fragment of tetanus neurotoxin

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.20 Å

Oligo State

monomer

Ligands

1 x TYR: TYROSINE(Non-covalent)

TYR.1: 4 residues within 4Å: Chain A: D.340, Y.355, A.357 Ligands: GLU.2 2 PLIP interactions: 1 Ligand-Ligand interactions, 1 interactions with chain A Water bridges: Y.1, A:Y.355

1 x GLU: GLUTAMIC ACID(Non-covalent)

GLU.2: 5 residues within 4Å: Chain A: G.341, N.342, R.352 Ligands: TYR.1, TRP.3 6 PLIP interactions: 4 interactions with chain A, 2 Ligand-Ligand interactions Hydrophobic interactions: A:N.342 Hydrogen bonds: A:N.342, W.3, W.3 Water bridges: A:R.352 Salt bridges: A:R.352

1 x TRP: TRYPTOPHAN(Non-covalent)

TRP.3: 8 residues within 4Å: Chain A: K.269, D.273, Y.274, N.342, R.352, I.401, D.404 Ligands: GLU.2 6 PLIP interactions: 4 interactions with chain A, 2 Ligand-Ligand interactions Hydrophobic interactions: A:Y.274, A:I.401 Hydrogen bonds: A:R.352, E.2, E.2 Water bridges: A:N.342

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Jayaraman, S. et al., Common binding site for disialyllactose and tri-peptide in C-fragment of tetanus neurotoxin. Proteins (2005)

Release Date

2005-03-15

Peptides

Tetanus toxin (Tentoxylysin): A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

Tetanus toxin (Tentoxylysin)

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