SMTL ID : 1w6n.1

X-RAY CRYSTAL STRUCTURE OF C2S HUMAN GALECTIN-1

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.65 Å

Oligo State

homo-dimer

Ligands

1 x SO4: SULFATE ION(Non-functional Binders)

SO4.1: 2 residues within 4Å: Chain A: P.109, R.111 1 PLIP interactions: 1 interactions with chain A Salt bridges: A:R.111

5 x BME: BETA-MERCAPTOETHANOL(Non-functional Binders)

BME.2: 4 residues within 4Å: Chain A: E.86, C.88, K.99, L.100 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:E.86 BME.3: 6 residues within 4Å: Chain A: R.18, R.20, C.130, V.131, A.132 Chain B: C.130 No protein-ligand interaction detected (PLIP) BME.4: 5 residues within 4Å: Chain B: C.16, C.88, I.89, T.90, K.99 2 PLIP interactions: 2 interactions with chain B Hydrogen bonds: B:K.99, B:K.99 BME.5: 5 residues within 4Å: Chain B: R.18, E.86, C.88, K.99, L.100 No protein-ligand interaction detected (PLIP) BME.6: 6 residues within 4Å: Chain B: R.18, R.20, E.86, C.130, V.131, A.132 No protein-ligand interaction detected (PLIP)

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Lopez-Lucendo, M.I.F. et al., Growth-Regulatory Human Galectin-1: Crystallographic Characterisation of the Structural Changes Induced by Single-Site Mutations and Their Impact on the Thermodynamics of Ligand Binding. J.Mol.Biol. (2004)

Release Date

2004-10-20

Peptides

GALECTIN-1: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
B

GALECTIN-1

Related Entries With Identical Sequence